Effects of dietary organic, inorganic, and nanoparticulate selenium sources on growth, hemato-immunological, and serum biochemical parameters of common carp (Cyprinus carpio)

Abstract

An 8-week feeding trial was conducted to compare the effects of supplementing (0.7 mg kg) different dietary selenium (Se) sources including organic [selenomethionine (SeMet)], inorganic [sodium selenite (NaSeO)], and nanoparticulate Se (nano-Se) on physiological responses of common carp, Cyprinus carpio juveniles (9.7 ± 0.1 g). Basal diet without Se supplementation used as control. Fish fed nano-Se supplemented diet had the highest weight gain (97.2 ± 10.8%) and feed efficiency ratio (42.4 ± 0.8%). Intestinal villi height was significantly taller in fish fed nano-Se diet than in the control group in both foregut and midgut sections. Serum glutathione peroxidase and superoxide dismutase activities were significantly higher in nano-Se and SeMet groups than in control and sodium selenite groups. Fish fed Se-supplemented diets had greater red blood cell counts and hematocrit and hemoglobin values than the control group (P < 0.05). Nano-Se and SeMet groups showed a significant increase in white blood cell counts, neutrophil percentage, and serum lysozyme activity than the other groups. Fish fed nano-Se diet had the highest serum hemolytic activity, total immunoglobulin, and total protein and albumin contents, as well as the lowest serum total cholesterol and low density lipoprotein levels (P < 0.05). Overall, significant improvements in growth performance, feed utilization, intestinal morphology, and hemato-immunological and serum biochemical parameters of common carp juveniles suggest nano-Se as an efficient source for providing dietary Se in this species.

Effect of Dietary Organic Selenium Supplementation on Growth Performance, Carcass Characteristics and Antioxidative Status of Growing Rabbits

“…A serum concentration of MDA is an index of lipid peroxidation and oxidative stress, and its levels depend upon the antioxidants (Saffari et al, 2018). In present findigs regarding antioxidant status, plasma MDA decreased with the supplementation of Se-yeast and Se-algae.…”

Combined or individual effects of dietary magnesium and selenium nanoparticles on growth performance, immunity, blood biochemistry and antioxidant status of Asian seabass ( Lates calcarifer ) reared in freshwater

“…These results suggest that the combination of NanoSe and NanoMg may improve the immune response of Asian seabass. Similarly, dietary NanoSe supplementation led to an increase in ACH 50 in common carp (Saffari et al, ) and red sea bream (Dawood et al, ). Moreover, Wang et al () demonstrated that administration of Mg‐supplemented diets can enhance the non‐specific immunity in juvenile grass carp.…”

“…Recently, Se nanoparticle (NanoSe), a novel Se form, has attracted considerable attention, due to its higher bioavailability and relatively low toxicity compared to other Se sources (Hu et al, ; Rezvanfar et al, ; Shi et al, ; Wang, Yan, & Fu, ). Several authors showed that dietary supplementation with NanoSe could improve growth performance, antioxidant defence system, immune response and muscle Se content in fish species studied (Ashouri, Keyvanshokooh, Salati, Johari, & Pasha‐Zanoosi, ; Dawood et al, ; Naderi, Keyvanshokooh, Salati, & Ghaedi, ; Saffari, Keyvanshokooh, Zakeri, Johari, & Pasha‐Zanoosi, ; Saffari et al, ; Zhou, Wang, Gu, & Li, ). Also, Mg nanoparticle as a feed additive has been reported to have antibacterial and antioxidative effects (Manuel y Keenoy et al, ; Tang & Lv, ).…”

Dietary nano‐selenium enhances antioxidant capacity and hypoxia tolerance of grass carp Ctenopharyngodon idella fed with high‐fat diet

“…Se as an essential nutrient for fish has been researched in many fish species, including grass carp (Liu et al, , ; Saffari, Keyvanshokooh, Zakeri, Johari, & Pasha‐Zanoosi, ; Xia et al, ; Zhou, Wang, Gu, & Li, ). Se nanoparticle (Nano‐Se) is the novel Se form and has attracted remarkable attention, as it exhibits higher bioavailability, lower toxicity and strong bioactivity in comparison with inorganic and organic Se (Saffari et al, , ; Zhou et al, ). Zhou et al () showed that Nano‐Se are more efficient in increasing muscle Se content compared to organic Se (selenomethionine, SeMet) in the crucian carp (Zhou et al, ).…”

“…is the novel Se form and has attracted remarkable attention, as it exhibits higher bioavailability, lower toxicity and strong bioactivity in comparison with inorganic and organic Se (Saffari et al, 2017(Saffari et al, , 2018Zhou et al, 2009). Zhou et al (2009) showed that Nano-Se are more efficient in increasing muscle Se content compared to organic Se (selenomethionine, SeMet) in the crucian carp (Zhou et al, 2009).…”