2008
DOI: 10.1016/j.tox.2008.07.066
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Effects of dichlorobenzene on acetylcholine receptors in human neuroblastoma SH-SY5Y cells

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Cited by 10 publications
(7 citation statements)
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“…Human neuroblastoma SH-SY5Y cells, obtained from ATCC (CRL-2266), were cultured as described previously [26], as were human osteosarcoma (HOS) cells, obtained from the Bioresource Collection and Research Center (Hsinchu, Taiwan) [27].…”
Section: Cell Culturementioning
confidence: 99%
“…Human neuroblastoma SH-SY5Y cells, obtained from ATCC (CRL-2266), were cultured as described previously [26], as were human osteosarcoma (HOS) cells, obtained from the Bioresource Collection and Research Center (Hsinchu, Taiwan) [27].…”
Section: Cell Culturementioning
confidence: 99%
“…Yan and colleagues found that PDCB affects calcium homeostasis in neural tissue by inhibition of nicotinic acetylcholine receptor ion channels [Yan et al 2008]. Subsequently PDCB mediated alteration in intracellular and extracellular calcium ion concentration in vitro might obstruct neuronal signaling leading to neuronal toxicity.…”
Section: Mode Of Pdcb Toxicitymentioning
confidence: 99%
“…Yan and colleagues found that PDCB affects calcium homeostasis in neural tissue by inhibition of nicotinic acetylcholine receptor ion channels [Yan et al . 2008].…”
Section: Mode Of Pdcb Toxicitymentioning
confidence: 99%
“…Oral administration of a radioactively-labeled 1,2-DCB to rats revealed that it can be distributed among all tissues, including skeletal muscle. In addition, it has been shown that DCB molecules can induce a rise in intracellular Ca 2+ in human neuronal SH-SY5Y cells [ 7 , 8 ]. Given this evidence, we hypothesized that 1,2-DCB can affect the functionality of skeletal muscle proteins, particularly the Ca 2+ -ATPase from sarcoplasmic reticulum (SERCA), a predominant protein of skeletal muscle, a hypothesis that has not previously been explored.…”
Section: Introductionmentioning
confidence: 99%