Effects of Corneal Scars and Their Treatment With Rigid Contact Lenses on Quality of Vision

Jong, Bram de; Meulen, Ivanka J.E. van der; Vliet, Johannes M. J. van; Lapid-Gortzak, Ruth; Nieuwendaal, Carla P.; Berg, Thomas

doi:10.1097/icl.0000000000000384

Cited by 17 publications

(13 citation statements)

References 17 publications

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“…Additionally, rigid corneal lenses allow for much greater tear exchange compared to scleral lenses, especially a sealed one, so atmospheric oxygen should be more available to the cornea with this approach [49,50], just as a SiHy lens is likely to allow for better tear exchange than a sealed scleral lens [51]. Rigid corneal lenses are useful in the visual rehabilitation of corneal scars because their capacity to neutralise any corneal irregularity outweighs any worsening of straylight [52]. Nevertheless, the prescribing of rigid corneal lenses has lost some favour for cosmetic purposes and for corneal disease cases in recent years because of the challenges associated with fitting this modality and because many patients find scleral lenses more comfortable [53].…”

Section: Rigid Corneal Lensesmentioning

confidence: 99%

“…Rigid corneal lenses can be considered for visual rehabilitation in scarred corneas and with corneal opacities after trauma or infection [52,[460][461][462]. More recently, semi-scleral contact lenses provide excellent visual acuity and comfort in patients with such irregular corneas [441, 463].…”

Section: Irregular Astigmatism From Infection Trauma Dystrophy or Degenerationmentioning

confidence: 99%

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BCLA CLEAR – Medical use of contact lenses

Jacobs

Carrasquillo²,

Cottrell

et al. 2021

Contact Lens and Anterior Eye

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The medical use of contact lenses is a solution for many complex ocular conditions, including high refractive error, irregular astigmatism, primary and secondary corneal ectasia, disfiguring disease, and ocular surface disease. The development of highly oxygen permeable soft and rigid materials has extended the suitability of contact lenses for such applications. There is consistent evidence that bandage soft contact lenses, particularly silicone hydrogel lenses, improve epithelial healing and reduce pain in persistent epithelial defects, after trauma or surgery, and in corneal dystrophies. Drug delivery applications of contact lens hold promise for improving topical therapy. Modern scleral lens practice has achieved great success for both visual rehabilitation and therapeutic applications, including those requiring retention of a tear reservoir or protection from an adverse environment. This report offers a practical and relevant summary of the current evidence for the medical use of contact lenses for all eye care professionals including optometrists, ophthalmologists, opticians, and orthoptists. Topics covered include indications for use in both acute and chronic conditions, lens selection, patient selection, wear and care regimens, and recommended aftercare schedules. Prevention, presentation, and management of complications of medical use are reviewed.

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Section: Rigid Corneal Lensesmentioning

confidence: 99%

Section: Irregular Astigmatism From Infection Trauma Dystrophy or Degenerationmentioning

confidence: 99%

BCLA CLEAR – Medical use of contact lenses

Jacobs

Carrasquillo²,

Cottrell

et al. 2021

Contact Lens and Anterior Eye

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“…Mihranyan et al took advantage of carboxylated cellulose nanowhiskers to enhance the mechanical properties of polyvinyl alcohol (PVA) for replacing conventional contact lenses. It was suggested that this combination could be flexible and have suitable optical properties [100]; however, constant usage of the contact lenses can cause corneal scar [101,102].…”

Section: Growth Factor Deliverymentioning

confidence: 99%

Bioengineering Approaches for Corneal Regenerative Medicine

Mahdavi

Abdekhodaie

Mashayekhan

et al. 2020

Tissue Eng Regen Med

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BACKGROUND: Since the cornea is responsible for transmitting and focusing light into the eye, injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual acuity. Aging is also a reason for corneal degeneration. Depending on the level of the injury, conservative therapies and donor tissue transplantation are the most common treatments for corneal diseases. Not only is there a lack of donor tissue and risk of infection/rejection, but the inherent ability of corneal cells and layers to regenerate has led to research in regenerative approaches and treatments. METHODS: In this review, we first discussed the anatomy of the cornea and the required properties for reconstructing layers of the cornea. Regenerative approaches are divided into two main categories; using direct cell/growth factor delivery or using scaffold-based cell delivery. It is expected delivered cells migrate and integrate into the host tissue and restore its structure and function to restore vision. Growth factor delivery also has shown promising results for corneal surface regeneration. Scaffold-based approaches are categorized based on the type of scaffold, since it has a significant impact on the efficiency of regeneration, into the hydrogel and non-hydrogel based scaffolds. Various types of cells, biomaterials, and techniques are well covered. RESULTS: The most important characteristics to be considered for biomaterials in corneal regeneration are suitable mechanical properties, biocompatibility, biodegradability, and transparency. Moreover, a curved shape structure and spatial arrangement of the fibrils have been shown to mimic the corneal extracellular matrix for cells and enhance cell differentiation. CONCLUSION: Tissue engineering and regenerative medicine approaches showed to have promising outcomes for corneal regeneration. However, besides proper mechanical and optical properties, other factors such as appropriate sterilization method, storage, shelf life and etc. should be taken into account in order to develop an engineered cornea for clinical trials.

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“…Korneal skar dokusu hem yarattığı opaklık hem de düzensiz astigmatizma nedeni ile görme keskinliğinde azalmaya neden olmakla beraber, sert kontakt lensle bu hastaların görme keskinliklerinin 20/20 seviyesinde bile bulunabileceği bilinmektedir. 32 Biz de çalışmamızda bu hastaların görme keskinliklerinin 20/200-20/40 aralığında olabileceğini öngördük, ancak elimizde net veri olmadığı için istatistiksel değerlendirmeye dâhil etmedik.…”

Section: Gereç Ve Yöntemlerunclassified

Pediatric Open Glob Injuries: Clinical Features and Long-Term Results

Yıldız¹,

Çakır²,

Beşek³

et al. 2020

Turkiye Klinikleri J Ophthalmol

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Oküler travma, çocuklarda kazanılmış görme kaybının en sık nedenlerinden biridir. 1 Her yıl 3,3-5,7 milyon çocuk oküler travmaya maruz kalmakta ve bunlardan 160.000-280.000'i hospitalizasyon gerektirecek kadar ciddi yaralanmaktadır. 2 Bu durumun çocuklarda yarattığı duygusal stresin yanı sıra, ülke ekonomisine de ciddi yük getirmektedir. 3 Oküler travmaların epidemiyolojik karakterleri bölgeden bölgeye çeşitli farklılıklar gösterse de dünya genelinde değişmeyen bu tip yaralanmaların %90'ının aslında önlenebilir nitelikte oluşudur. 4

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Effects of Corneal Scars and Their Treatment With Rigid Contact Lenses on Quality of Vision

Cited by 17 publications

References 17 publications

BCLA CLEAR – Medical use of contact lenses

BCLA CLEAR – Medical use of contact lenses

Bioengineering Approaches for Corneal Regenerative Medicine

Pediatric Open Glob Injuries: Clinical Features and Long-Term Results

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