Effects of cardiac rehabilitation in patients with metabolic syndrome after coronary artery bypass grafting

Onishi, Tomo; Shimada, Kazunori; Sunayama, Satoshi; Ohmura, Hirotoshi; Sumide, Takahiro; Masaki, Yoshiyuki; Fujita, Kosuke; Nishitani, Miho; Kume, Atsumi; Sato, Hiroyuki; Naito, Hisashi; Kawai, Sachio; Amano, Atsushi; Daida, Hiroyuki

doi:10.1016/j.jjcc.2009.01.004

Cited by 27 publications

(37 citation statements)

References 34 publications

(38 reference statements)

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“…Patients in the supervised exercise group had significant improvements in triglyceride, LDL-cholesterol and HDL-cholesterol, whereas the home-based group showed improvement in HDLcholesterol only. In a recent study, Onishi et al 29 also reported CR exercise training might improve LDL-cholesterol and total cholesterol in CABG patients with metabolic syndrome. Additionally, metabolic scoring defined by the number of the modified Adult Treatment Panel criteria of the US National Cholesterol Education Program was significantly improved.…”

Section: Lipid Profilementioning

confidence: 94%

“…After training, the v  O 2peak and peak lower limb torques significantly increased, and the circumferences of thigh and calf were also increased. In a recent study, Onishi et al 29 reported a 6-month aerobic and resistance training program also improved v  O 2peak and isokinetic peak torques of knee extensor and flexor in patients after CABG. It appears that a combined aerobic and resistance training program significantly increased exercise tolerance and lower limb muscle strength.…”

Section: Muscular Strengthmentioning

confidence: 96%

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Exercise Training for Patients After Coronary Artery Bypass Grafting Surgery

Lan¹,

Chen²,

Lai³

2012

Acute Coronary Syndromes

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Section: Lipid Profilementioning

confidence: 94%

Section: Muscular Strengthmentioning

confidence: 96%

Exercise Training for Patients After Coronary Artery Bypass Grafting Surgery

Lan¹,

Chen²,

Lai³

2012

Acute Coronary Syndromes

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“…Regular physical exercise is associated with a reduction of inflammatory markers and ischemic events in patients with CAD. 25) We also found that CR for 6 months ameliorated inflammatory states in patients with metabolic syndrome after CABG 14) and that voluntary exercise improves the progression of endothelial dysfunction and atherosclerotic lesion formation through anti-inflammatory effects in an experimental study. 26) In the present study, the change of plaque volume and vessel remodeling did not differ significantly between the PII-CR and non PII-CR groups.…”

Section: Discussionmentioning

confidence: 57%

“…Rehabilitation protocol: The CR program consisted of warmup stretching, aerobic exercise, resistance training, and a cooldown, and was scheduled once or twice weekly for 6 months as described. 14,15) Briefly, about 60 minutes of aerobic exercise consisted of cycling on an ergometer and walking on a treadmill and on an indoor track. The exercise intensity was prescribed at the anaerobic threshold (AT) of each individual determined by ergometry using expiratory gas analysis or at a value of 11-13 on the standard Borg rating of perceived exertion (RPE) scale.…”

mentioning

confidence: 99%

Effects of Phase II Comprehensive Cardiac Rehabilitation on Coronary Plaque Volume After Acute Coronary Syndrome

et al. 2015

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SummaryThe present study aimed to determine the effects of phase II (PII) comprehensive cardiac rehabilitation (CR) on coronary plaque volume in patients after acute coronary syndrome (ACS).We assigned 46 patients with ACS who had undergone standard phase I CR into groups who proceeded with PII-CR (PII-CR; n = 21) and those who did not (non-PII-CR; n = 25). We then measured anthropometric parameters and daily physical activity using a pedometer for up to 60 days. The isokinetic strength of the knee extensor and flexor muscles and exercise tolerance were tested and non-culprit lesions were analyzed using volumetric intravascular ultrasound at baseline and 6 months later.Baseline characteristics did not significantly differ between the two groups and exercise tolerance was significantly improved in both. Waist size and fat weight were significantly decreased, and muscle strength was significantly increased in the PII-CR group but not in the non-PII-CR group. The percent change in plaque volume (primary endpoint) did not differ significantly between the two groups. The percent change in plaque volume was significantly and negatively correlated with daily physical activity.Although risk factors, muscle strength, and exercise tolerance were improved by PII-CR, plaque regression did not differ significantly between the two study groups. A significant correlation between percent change in coronary plaque volume and physical activity was observed. A comprehensive phase II-CR, including frequent supervised exercise sessions and a program encouraging an increase in daily physical activity, may reduce plaque volume in patients after ACS (UMIN000006038). (Int Heart J 2015; 56: 597-604) Key words: Intravascular ultrasound, Physical activity A cute coronary syndrome (ACS) is an important public health problem, and approximately 42,000 Japanese die of myocardial infarction every year. 1) Comprehensive cardiac rehabilitation (CR) is an established program for patients with ACS after treatment by coronary artery bypass grafting (CABG) and heart failure 2) that helps to modify coronary risk factors and improve quality of life.3,4) A metaanalysis has shown that CR reduces all-cause mortality by 20% and cardiac mortality by 25%.5) The mechanisms through which CR improves mortality risk are attributed to improvements in lipid profiles, glucose metabolism, neurohormonal factors, autonomic nerve system, endothelial function, and reduced vascular inflammation. Atherosclerotic plaque regression and/or stabilization are upstream for cardiovascular events. Indeed, previous findings suggest that multifactorial intervention could retard plaque progression and stabilization. 6,7) Editorial p.583Recent advances in coronary plaque imaging such as intravascular ultrasound (IVUS) enable the visualization of plaque morphology and accurate measurement of plaque volume. 8,9) Indeed, our and other studies have shown that statins significantly reduce plaque volume in patients with ACS and stable coronary artery disease (CAD). [10][11][12] However, th...

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“…Although various studies were conducted to test the effect of CR on MetS patients, there are still inconsistent results on the effect of CR on reverse MetS and also its components. For instance, although several studies have failed to find any significant effect of CR on high density lipoprotein cholesterol (HDL-C),[161718] some others have even documented its significant effects on HDL-C.[19202122] The same pattern can be observed in other metabolic factors too. [161718192021222324252627282930] Therefore, the present article aimed to summarize and if possible, perform a meta-analysis on published data about the effect of CR on MetS reduction rate and its components or related metabolic and anthropometric markers.…”

Section: Introductionmentioning

confidence: 99%

Effect of cardiac rehabilitation on metabolic syndrome and its components: A systematic review and meta-analysis

Sadeghi¹,

Salehi‐Abargouei²,

Kasaei

et al. 2016

J Res Med Sci

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Background:Although the effect of cardiac rehabilitation (CR) on cardiovascular disease (CVD) prognosis has been well-documented by several systematic reviews, none have focused on the effect of CR on metabolic syndrome (MetS) and its related components. Therefore, the present systematic review and meta-analysis was conducted to assess the effect of CR on MetS and its components.Materials and Methods:PubMed, SCOPUS, Cochrane library, and Google Scholar database were searched up to February 2014 with no date and language restrictions. The random effects model was used to assess the overall effect of CR on MetS prevalence and the change in metabolic or anthropometric measures.Results:Fifteen studies with 19,324 subjects were included in the present systematic review and meta-analysis. Our analysis showed that the CR could significantly reduce MetS prevalence [reduction rate: 0.25, 95% confidence interval (CI): 0.21, 0.3, P value <0.001; P value for heterogeneity <0.001, I-squared: 86.2%]. Additionally, results showed the protective role of CR on all MetS components including high density lipoprotein cholesterol [mean difference (MD): 2.13 mg/dL, 95% CI: 1.17, 3.1], triglyceride (MD: -27.45 mg/dL, 95% CI: −36.92, −17.98), systolic blood pressure (SBP) (MD: −6.20 mmHg, 95% CI: -8.41, −3.99), diastolic blood pressure (DBP) (MD: −2.53 mmHg, 95% CI: −3.64, −1.41), fasting blood sugar (FBS) (MD: −6.42 mg/dL, 95% CI: −6.85, −5.99), and waist circumference (WC) (MD: −2.25 cm, 95% CI: −3.15, −1.35).Conclusion:CR has resulted in improvement in MetS and its entire components, and could be considered as a useful tool for MetS patients, especially among those with CVD.

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Effects of cardiac rehabilitation in patients with metabolic syndrome after coronary artery bypass grafting

Abstract: These results suggest that CR might be useful for patients with MetS after CABG.

Cited by 27 publications

References 34 publications

Exercise Training for Patients After Coronary Artery Bypass Grafting Surgery

Exercise Training for Patients After Coronary Artery Bypass Grafting Surgery

Effects of Phase II Comprehensive Cardiac Rehabilitation on Coronary Plaque Volume After Acute Coronary Syndrome

Effect of cardiac rehabilitation on metabolic syndrome and its components: A systematic review and meta-analysis

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