Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

Yang, Luwei; Chai, Peiwei; Yu, Jie; Fan, Xianqun

doi:10.20892/j.issn.2095-3941.2020.0559

Cited by 95 publications

(81 citation statements)

References 73 publications

(20 reference statements)

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“…According to Yang et al 96 conducted a comprehensive analysis of a total of 63,019 COVID-19 patients in 19 retrospective studies, about 6% of patients had tumor with COVID-19, and the mortality rate was significantly higher than that of non-cancer patients (14.6% vs 3.8%), especially in active tumors. There are many types of tumors.…”

Section: Covid-19 and Blood Cancer Patientsmentioning

confidence: 99%

SARS-CoV-2 Infection: Differences in Hematological Parameters Between Adults and Children

Liu¹,

She²,

Bai³

et al. 2021

IJGM

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Since December 2019, corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic, posing a huge threat to human health, and the current epidemic prevention situation is still severe. Hematological parameters directly reflect the damage of SARS-CoV-2 to human blood cells, which can better assess the severity and prognosis of patients infected with COVID-19, but hematological parameters have some differences between adults and children. This article comprehensively reviews the differences in hematological parameters between adults and children after SARS-CoV-2 infection, and provides a reference for the diagnosis and treatment of COVID-19.

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Section: Covid-19 and Blood Cancer Patientsmentioning

confidence: 99%

SARS-CoV-2 Infection: Differences in Hematological Parameters Between Adults and Children

Liu¹,

She²,

Bai³

et al. 2021

IJGM

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show abstract

“…Higher risks of mortality were observed for comorbidities such as cancer, bacterial infections, heart disease, other symptoms involving the circulatory and respiratory systems and kidney failure. A systematic review and meta-analysis conducted by Yang and colleagues (2021) [25] identified that patients with a cancer diagnosis were more susceptible to COVID-19 and were at increased odds of dying from COVID-19. Similar findings were observed in other studies, including meta-analyses for coronary heart disease and COVID-19 [26,27].…”

Section: Plos Onementioning

confidence: 99%

Trends in COVID-19 case-fatality rates in Brazilian public hospitals: A longitudinal cohort of 398,063 hospital admissions from 1st March to 3rd October 2020

et al. 2021

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Background Almost 200,000 deaths from COVID-19 were reported in Brazil in 2020. The case fatality rate of a new infectious disease can vary by different risk factors and over time. We analysed the trends and associated factors of COVID-19 case fatality rates in Brazilian public hospital admissions during the first wave of the pandemic. Methods A retrospective cohort of all COVID-19-related admissions between epidemiological weeks 10–40 in the Brazilian Public Health System (SUS) was delimited from available reimbursement records. Smoothing time series and survival analyses were conducted to evaluate the trends of hospital case fatality rates (CFR) and the probability of death according to factors such as sex, age, ethnicity, comorbidities, length of stay and ICU use. Results With 398,063 admissions and 86,452 (21.7%) deaths, the overall age-standardized hospital CFR trend decreased throughout the period, varying from 31.8% (95%CI: 31.2 to 32.5%) in week 10 to 18.2% (95%CI: 17.6 to 18.8%) in week 40. This decreasing trend was observed in all sex, age, ethnic groups, length of stay and ICU admissions. Consistently, later admission (from July to September) was an independent protective factor. Patients 80+ year old had a hazard ratio of 8.18 (95% CI: 7.51 to 8.91). Ethnicity, comorbidities, and ICU need were also associated with the death risk. Although also decreasing, the CFR was always around 40–50% in people who needed an ICU admission. Conclusions The overall hospital CFR of COVID-19 has decreased in Brazilian public hospitals during the first wave of the pandemic in 2020. Nevertheless, during the entire period, the CFR was still very high, suggesting the need for improving COVID-19 hospital care in Brazil.

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“…The selected categories were patients with active advanced disease, patients receiving immunosuppressive treatment, and patients who had finished their cancer treatment in the past 6 months. 5 Consequently, patients treated with radiotherapy were also prioritised.…”

mentioning

confidence: 99%

Acute tolerance of Moderna mRNA-1273 vaccine against COVID-19 in patients with cancer treated with radiotherapy

Scoccianti

Paoli

Leonulli

et al. 2021

The Lancet Oncology

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Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants

Cited by 95 publications

References 73 publications

SARS-CoV-2 Infection: Differences in Hematological Parameters Between Adults and Children

SARS-CoV-2 Infection: Differences in Hematological Parameters Between Adults and Children

Trends in COVID-19 case-fatality rates in Brazilian public hospitals: A longitudinal cohort of 398,063 hospital admissions from 1st March to 3rd October 2020

Acute tolerance of Moderna mRNA-1273 vaccine against COVID-19 in patients with cancer treated with radiotherapy

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