Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect

Henmi, Hirofumi; Endo, Toshiaki; Kitajima, Yoshimitsu; Manase, Kengo; Hata, Hiroshi; Kudo, Ryuich

doi:10.1016/s0015-0282(03)00657-5

Cited by 78 publications

(44 citation statements)

References 15 publications

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“…The cohort study with a control group by Hemni et al [34], in which patients with a polycystic ovarian syndrome received a high-dose vitamin C supplementation, could show a significant increase in progesterone levels of [10 ng/ml in the intervention group compared to the control group. Despite missing basis characteristics and the dropouts exclusively in the control group, the quality of the study still allows for a correlation between the observed effect and the intervention.…”

Section: Discussionmentioning

confidence: 99%

“…The cohort study with comparison group performed by Hemni et al [34], in which patients with a polycystic ovarian syndrome received high-dose vitamin C supplements, could show an increase in progesterone levels of [10 ng/ml as well as a significant increase in pregnancy rate in the intervention group compared to the control group. However, the side effects of a dosage of 750 mg vitamin C, which was far higher than the recommended daily dosage of 100 mg/day, were not considered.…”

Section: Individual Quality Assessment Of the Studiesmentioning

confidence: 99%

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The effect of micronutrient supplements on female fertility: a systematic review

Grajecki

Zyriax

2012

Arch Gynecol Obstet

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Section: Discussionmentioning

confidence: 99%

Section: Individual Quality Assessment Of the Studiesmentioning

confidence: 99%

The effect of micronutrient supplements on female fertility: a systematic review

Grajecki

Zyriax

2012

Arch Gynecol Obstet

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“…Vitamin C supplementation as antioxidant in dose dependent manner in men may improve sperm quality [76]. It's supplementation also increases progesterone levels in infertile women with luteal phase defect [77].…”

Section: Vitamin C and Fertilitymentioning

confidence: 99%

Vitamin C in Disease Prevention and Cure: An Overview

et al. 2013

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The recognition of vitamin C is associated with a history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radical damage. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. However the significance and beneficial effect of vitamin C in respect to human disease such as cancer, atherosclerosis, diabetes, neurodegenerative disease and metal toxicity however remains equivocal. Thus further continuous uninterrupted efforts may open new vistas to understand its significance in disease management.

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“…In this respect, it was observed that ascorbic acid (an antioxidant) increases progesterone concentration in women who exhibit a defective luteum phase (Henmi et al, 2003). In ovariectomized sheep, administration of 20 mg caffeine did not affect the concentration of other reproductive hormones such as FSH (Follicle-Stimulating Hormone) and LH (Luteinizing Hormone).…”

Section: Progesteronementioning

confidence: 99%

Oxidative status and fertility of ewes supplemented coffee pulp during estrous synchronization and early pregnancy

Salinas-Rios

Sánchez-Torres

Dı́az-Cruz

et al. 2016

Rev Colomb Cienc Pecu

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Oxidative status and fertility of ewes supplemented coffee pulp during estrous synchronization and early pregnancy ¤ Estado oxidativo y fertilidad en ovejas suplementadas con pulpa de café durante la sincronización estral y gestación tempranaEstado oxidativo e fertilidade nas ovelhas suplementadas com a polpa de café durante sincronização do estro e gestação inicial SummaryBackground: it is known that coffee pulp can modify the oxidative status and fertility in dairy cows. Objective: to evaluate the effect of dietary supplementation with coffee pulp on the antioxidant capacity, lipid oxidation and reproductive characteristics of ewes during estrous synchronization and early gestation. Methods: forty Dorset-Suffolk crossbred ewes with 3 or 4 parturitions were allocated to two treatments: T0 (n = 21), ewes supplemented with 450 g of a control feed; and T1 (n = 19), ewes supplemented with 450 g of the feed with 25% coffee pulp. Supplementation began 14 days before estrous synchronization and ended 25 days after breeding. During estrous synchronization, progestogen (CIDR, Controlled Internal Drug Release) ¤ To cite this article: Salinas T, Sánchez MT, Dìaz A, Cordero JL, Càrdenas M, Hernàndez J, Nava C, Nieto R. Oxidative status and fertility of ewes supplemented coffee pulp during estrous synchronization and early pregnancy. Rev Colomb Cienc Pecu 2016; 29:255-263.

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Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect

Cited by 78 publications

References 15 publications

The effect of micronutrient supplements on female fertility: a systematic review

The effect of micronutrient supplements on female fertility: a systematic review

Vitamin C in Disease Prevention and Cure: An Overview

Oxidative status and fertility of ewes supplemented coffee pulp during estrous synchronization and early pregnancy

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