Effects of Antibiotics on Impacted Aquatic Environment Microorganisms

Araújo, Lívia Caroline Alexandre de; Silva, Sivoneide Maria da; Sá, Rafael de Queiroz Cavalcanti de Artur; Lima, Adilson Celestino de; Barbosa, Amanda Virgínia; Silva, Jaqueline dos Santos; Leite, Kaleen Massari; Júnior, Wellenilton Jose do Nascimento; Silveira-Filho, Vladimir da Mota; Mendes-Marques, Carina Lucena; Silva, Francisco Henrique da; Oliveira, Maria Betânia Melo de

doi:10.5772/intechopen.93910

Cited by 2 publications

(2 citation statements)

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“…Water systems are an important reservoir for antibiotics and ARGs (16, 17) . The accumulation of antibiotics and ARGs in the water could act as a long-term selective pressure, thereby reducing the diversity of microorganisms and reshaping the microbial community, and further polluting the water environment (18, 19) . As a result, the bioaccumulation of antibiotics in poultry, aquatic products, and vegetables will therefore directly or indirectly enter the human body via the food chain.…”

Section: Introductionmentioning

confidence: 99%

Occurrence, risk assessment of antibiotics and antimicrobial resistance inEscherichia coliin typical rivers of Sichuan

Sha,

Wu,

Zhou

et al. 2024

Preprint

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Worldwide interest has been generated by the presence and distribution of antibiotics and antibiotic resistance genes (ARGs) in rivers. However, there was a dearth of research on the contamination of Sichuan province’s typical rivers with antibiotics. In this study, the residual level of antibiotics in 42 national/provincial sites of 9 rivers was analyzed by UPLC-MS/MS, the ecological risk level was evaluated using risk assessment method, and the drug resistance ofE. coliin water was evaluated by Kirby-Bauer method. Redundancy analysis demonstrated how residual antibiotics affect the structure of the microbial community in the Minjiang River basin (RDA). Nine rivers all contained antibiotics. Among them, the MinJiang, TuoJiang, and JiaLingJiang rivers were severely contaminated with antibiotic concentrations ranging from 0.29 to 2233.71 ng/L. The Sichuan Basin’s antibiotic pollution level was significantly higher when compared to other Sichuan zones, which was consistent with the region’s high population density. Additionally, it was discovered that 9.77% of theE. coliisolated from 9 rivers had antibiotic resistance, and more than 5.8% of them had multidrug resistance. Moreover, Norfloxacin, amoxicillin, ampicillin, and tetracycline were the main risk factors for high ecological risk in 26 of the 42 monitoring sites. Additionally, there is a strong correlation between the microbial community change and residual antibiotic. These results offered some reference information regarding the distribution of antibiotics and ARGs in typical rivers in the Chinese province of Sichuan, and this study showed that more attention needs to be paid to antibiotic pollution in Sichuan’s typical rivers.

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Section: Introductionmentioning

confidence: 99%

Occurrence, risk assessment of antibiotics and antimicrobial resistance inEscherichia coliin typical rivers of Sichuan

Sha,

Wu,

Zhou

et al. 2024

Preprint

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“…The pesticides used on farms or yards can pollute groundwater and surface water systems that feed the drinking water sources. Pharmaceutical chemicals, often known as emerging pollutants, which include antibiotics, are among the eco-toxicants that affect these ecosystems. , In recent years, the presence of antibiotic drugs in wastewater has been increased and caused the environmental pollution. , The pharmaceutical industry leads to the discharge of wastewater that has not been appropriately treated and is full of biorecalcitrant organic chemicals that are difficult to break down using traditional biological treatment methods . Linezolid (LIN), which is chemically known as (( S )-N-[[3-fluoro-4(4-morpholiny)-phenyl-2-oxo-5-oxazolidinyl]methyl]-acetamide, is one of world’s most significant commercial antibiotics used, because of its high bacterial resistance and large spectrum inhibition against micro-organisms. − However, the overuse of the linezolid antibiotic drug poses several adverse effects on human health, causing different adverse effects such as vomiting, headache, fungal infection, abdominal pain, tongue discoloration, rapid swelling, diarrhea, nausea, and low blood glucose. − Therefore, to avoid the risk of side effects of linezolid, it is very important to determine linezolid antibiotic in the biological samples.…”

Section: Introductionmentioning

confidence: 99%

A Reusable Nickel Oxide Reduced Graphene Oxide Modified Platinum Electrode for the Detection of Linezolid Drug

Buledi

Solangi

Mallah

et al. 2023

Ind. Eng. Chem. Res.

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Linezolid is most widely used antibiotic that inhibits different bacteria and micro-organisms. The overuse of linezolid causes several health complications, such as vomiting, tongue decolorization, and low blood glucose. An efficient and sensitive electrochemical sensor based on a NiO and reduced graphene oxide nanocomposite with a modified platinum electrode (NiO/rGO/PtE) was therefore developed for the monitoring of the linezolid drug. The confirmation of synthesis of graphene oxide and NiO/rGO was conducted through several physicochemical characterization techniques. The Fourier transform infrared spectroscopy results confirmed the Ni−O symmetric and antisymmetric stretching frequency at 741.4 and 732.1 cm −1 , Xray diffraction spectroscopy revealed exceptional crystallinity, while the size of the prepared materials, which was confirmed through atomic force microscopy, was determiend to be 1.675 nm. The incorporation of NiO into GO sheets is visualized through scanning electron microscopy images. Cyclic voltammetry and electrochemical impedance spectroscopy techniques were implemented to assess the electrochemical activity and the conductivity of NiO/rGO/PtE. Under the optimized conditions (phosphate buffer with a pH value of 6.0, scan rate of 70 mV/s, and linear dynamic range (LDR) value between 0.1 and 90 μM), the engineered sensor NiO/rGO/PtE manifested an excellent response for linezolid. The limit of detection (LOD) value of proposed technique for monitoring linezolid was computed to be 0.0031 μM, which was the lowest possible detection limit, compared to the literature. The anti-interference pattern and long-term stability further demonstrated the efficiency and reliability of NiO/rGO/PtE. The analytical application of NiO/rGO/PtE for linezolid was examined in urine samples as well as a commercial pharmaceutical sample. The sensitivity and reliability at repeated runs of modified sensor suggest that it could be used for the onsite detection of linezolid. Experiments have been conducted regarding the application of a fabricated NiO/rGO/PtE sensor as an effective and simple detection tool for antibiotics with a lower LOD than that of the reported electrochemical sensors for linezolid.

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Effects of Antibiotics on Impacted Aquatic Environment Microorganisms

Cited by 2 publications

References 83 publications

Occurrence, risk assessment of antibiotics and antimicrobial resistance inEscherichia coliin typical rivers of Sichuan

Occurrence, risk assessment of antibiotics and antimicrobial resistance inEscherichia coliin typical rivers of Sichuan

A Reusable Nickel Oxide Reduced Graphene Oxide Modified Platinum Electrode for the Detection of Linezolid Drug

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