Effects of α-Methyinoradrenaline and α-Methyldopamine in Reserpine-Induced Ulcers in Rats

Abstract

α-Methyldopamine and α-methylnoradrenaline administered intraperitoneally afforded significant protection in reserpine-induced ulcers in rats. The optimal doses were 2 and 4 mg/kg. Lower and higher doses were less effective. α-Methyldopamine and α-methylnoradrenaline probably act by reestablishing the normal adrenergic tone which is diminished in reserpine-induced ulcers.