Effects of aerobic exercise induced oxidative stress on energy regulatory hormones of irisin and nesfatin-1 in healthy females

Abstract

Objectives: Exercise is an important tool to stimulate oxidative stress and metabolic demands. We intended to evaluate impact of aerobic exercise on oxidative stress parameters and their relationships between irisin and nesfatin-1 levels. Material and Method: Total of ten healthy sedentary female subjects exercise for a 30 min of aerobic running exercise work intensity corresponded to associated their anaerobic threshold. Venous blood samples were taken before and at the end of the exercise. Serum irisin nesfatin-1 and TAS and TOS levels were analyzed using ELISA methods. Results: Exercise caused increase of irisin (11%) and nesfatin-1 (12%) levels. During exercise a decrease in TAS (-11%) and increased in TOS (29%) levels were observed. There was a significant correlation between changes of irisin and TAS levels (R=-0.67594, p=0.03). Conclusion: Consequently, exercise induced skeletal muscle activity may cause increase in oxidative stress, irisin and nesfatin-1 levels. Irisin hormone may be a secreted against to increased exercise-induced increased oxidative stress muscle activity.

Effects of physical activity and exercise on Nucleobindin‐2 gene expression and Nesfatin‐1 concentration: A rapid review

“…Uğraş et al also investigated the effect of a 30 min aerobic running exercise at an anaerobic threshold on Nesfatin‐1 concentration in females. Nesfatin‐1 concentration increased 12% responses to exercise 61 …”

“…From the 36 included studies, 23 examined humans 41–63 with 13 examining animal models 64–76 . Studies investigated the effects of chronic exercise training 41–51,63 and acute exercise 48,52–62 in humans. One study compared the effect of chronic and acute exercise 48 .…”

“…Adipose tissue, 11 the central nervous system, 1 and the peripheral nervous system 77 synthesize Nesfatin‐1, which is then released into the bloodstream. Numerous studies have examined the influence of exercise on Nesfatin‐1 concentration in a wide range of exercise protocols in both humans 41–63 and animals 64–76 . Having examined the body of available literature, the key finding is that Nesfatin‐1 concentration is induced by numerous modes of exercise.…”

“…The purpose of conducting this review is to assess the existing research evidence regarding the impact of exercise on Nucleobindin-2 (NUCB2) gene expression and Nesfatin-From the 36 included studies, 23 examined humans with 13 examining animal models. [64][65][66][67][68][69][70][71][72][73][74][75][76] Studies investigated the effects of chronic exercise training [41][42][43][44][45][46][47][48][49][50][51]63 and acute exercise 48,[52][53][54][55][56][57][58][59][60][61][62] in humans.…”

Circulating irisin and its connection with indices of body composition in aerobic and anaerobic endurance professional athletes: a case-control study

“…However, subjects enrolled in the Huh et al [22] study; their MBIs were all above 37 kg/m2, while those of Stengel et al [17] had a wide range of BMIs. Nevertheless, irisin, a new myokine, has recently been linked to human exercise-induced changes in oxidative stress and antioxidant defense, and its concentrations were unaffected by increased training volume or intensity [29].…”