Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

Oh, Eok Soo; Yoo, Ji Myong; Lee, Jung Eun; Hyun, Sa Saeng; Ko, Il Sun; Chu, Sang Hui

doi:10.1002/nur.21608

Cited by 33 publications

(29 citation statements)

References 31 publications

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“…The present study demonstrates that even though serum NTX levels were not decreased by combined exercise, there were significant increases in the serum sALP levels, showing the potential for combined exercise to positively affect bone quality in postmenopausal women. Previous studies have shown the positive effect of exercise on bone health in post-menopausal women, usually by a reduction in bone loss [22]. The participants of this study did not always show extremely high bone turnover.…”

Section: Discussionmentioning

confidence: 41%

The effects of combined training on bone metabolic markers in postmenopausal women

et al. 2016

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KEYWORDSExercise; Bone formation marker; Post-menopausal women SummaryObjectives. -Exercise plays an important role in maximizing and subsequent reduction of the maximum rates of bone loss. The purpose of this study was to determine whether 16 weeks of combined exercise in postmenopausal would affect bone metabolism. Results. -After the training period, postmenopausal significantly (P < 0.05) increase their muscle functionality (14% to 26.5%). Levels of NTX were not affected but there was a significant increase in bone synthesis (ALP: 12.5% to 15.9%), while there is no change in bone resorption. Combined training appears to be useful in improving total muscular performance and potentially in bone density. © 2016 Elsevier Masson SAS. All rights reserved. Résultats. -Après la période de formation, les femmes post-ménopausées ont vu la fonctionnalité des muscles augmenter significativement (p < 0,05) (14-26,5 %). Les niveaux de NTX n'ont pas été affectés, mais il y avait une augmentation significative de la synthèse osseuse (ALP : 12,5-15,9 %), alors qu'il n'y a aucun changement dans la réabsorption osseuse. La formation combinée semble être utile dans l'amélioration de la performance musculaire totale et, potentiellement, dans l'augmentation de la densité osseuse. MOTS CLÉS

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Section: Discussionmentioning

confidence: 41%

The effects of combined training on bone metabolic markers in postmenopausal women

et al. 2016

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“…Numerous studies have investigated the relationship between serum 25(OH)D levels and individual body composition. Calcium and vitamin D were positively associated with bone health in several studies . A study involving a nationwide sample of Koreans aged 40 years and older showed a lower mean value of appendicular skeletal muscle mass index (ASSMI) in men, but not in women, with hypovitaminosis, defined as serum 25(OH)D < 20 ng/mL .…”

Section: Discussionmentioning

confidence: 99%

“…7,9 Previous studies have indicated a significant association between serum vitamin D and individual components of abnormal body composition, manifesting as osteoporosis, sarcopenia, and obesity. [10][11][12][13][14][15][16] Besides vitamin D having individual protective effects on either bone or muscle mass and modulating body fat accumulation, 7,8,[17][18][19] vitamin D as a single factor displaying combined effects, such as on both bone and muscle mass, has been suggested. 12 However, few studies have examined the relationship between serum vitamin D with combined abnormalities in body composition.…”

Section: Introductionmentioning

confidence: 99%

Association of serum vitamin D with osteosarcopenic obesity: Korea National Health and Nutrition Examination Survey 2008–2010

Kim

Lee

Kye

et al. 2016

J cachexia sarcopenia muscle

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BackgroundSerum vitamin D levels have been reported to be associated with individual components of body composition. However, the relationship between serum vitamin D and combined indices of adverse body composition is largely unknown. This cross‐sectional study examined the association between serum vitamin D and osteosarcopenic obesity in a nationally representative sample of middle‐aged and older adults.MethodsWe analysed the Korea National Health and Nutrition Examination Surveys (IV and V) conducted in 2008–2010, consisting of 5908 (2485 men, 3423 women) aged ≥ 50 years. Serum vitamin D levels were determined by radioimmunoassay, and body composition was evaluated by dual‐energy x‐ray absorptiometry. The association between serum vitamin D levels and the number of abnormalities in body composition, including osteosarcopenic obesity, a low bone and muscle mass with concurrent high fat mass, was analysed by multinomial logistic regression adjusting for covariates.ResultsIn men, after controlling for covariates, higher vitamin D levels were associated with a significantly reduced likelihood of the number of phenotypes of adverse body composition (P for trend < 0.05). Those in the highest tertile group of serum vitamin D levels, compared with those in the lowest tertile, were less likely to have adverse body composition, numbering one (odds ratio [OR] = 0.67, 95% confidence interval [CI]: 0.49, 0.92), two (OR = 0.49, 95% CI: 0.33, 0.73), and three (osteosarcopenic obesity; OR = 0.42, 95% CI: 0.26, 0.67). In women, those in the highest tertile group of serum vitamin D levels, compared with those in the lowest tertile, were less likely to have osteosarcopenic obesity (OR = 0.55, 95% CI: 0.33, 0.93). Vitamin D deficiency (<20 ng/mL) in men was significantly associated with an increased likelihood of a higher number of adverse body composition, especially for osteosarcopenic obesity (OR = 2.08, 95% CI: 1.42, 3.03). Vitamin D deficient women, compared with those having normal levels of serum vitamin D, were also more likely to demonstrate osteosarcopenic obesity (OR = 1.99, 95% CI: 1.30, 3.05).ConclusionsA high serum vitamin D level in mid‐ and late‐life was associated with reduced odds of multiple adverse body composition, especially osteosarcopenic obesity, suggesting potential health benefits of maintaining adequate levels of vitamin D.

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“…Less is known about whether such interventions affect patient satisfaction or QOL [17, 18]. Most of these RCTs examining OP patient-education interventions have been multifaceted or lengthy [7, 12, 13, 15, 16], which are not scalable. To date, only one RCT has examined the effect of an OP education intervention on QOL, reporting a beneficial effect after both three months and one year [16].…”

Section: Introductionmentioning

confidence: 99%

Effects of a DXA result letter on satisfaction, quality of life, and osteoporosis knowledge: a randomized controlled trial

Edmonds

Cram

Lou

et al. 2016

BMC Musculoskelet Disord

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BackgroundUndiagnosed, or diagnosed and untreated osteoporosis (OP) increases the likelihood that falls result in hip fractures, decreased quality of life (QOL), and significant medical expenditures among older adults. We tested whether a tailored dual energy x-ray absorptiometry (DXA) test result letter and an accompanying educational bone-health brochure affected patient satisfaction, QOL, or OP knowledge.MethodsThe Patient Activation after DXA Result Notification (PAADRN) study was a double-blinded, pragmatic, randomized trial which enrolled patients from 2012 to 2014. We randomized 7,749 patients presenting for DXA at three health care institutions in the United States who were ≥ 50 years old and able to understand English. Intervention patients received a tailored letter four weeks after DXA containing their results, 10-year fracture risk, and a bone-health educational brochure. Control patients received the results of their DXA per the usual practices of their providers and institutions. Satisfaction with bone health care, QOL, and OP knowledge were assessed at baseline and 12- and 52-weeks after DXA. Intention-to-treat analyses used multiple imputation for missing data and random effects regression models to adjust for clustering within providers and covariates.ResultsAt 12-weeks 6,728 (86.8 %) and at 52-weeks 6,103 participants (78.8 %) completed their follow-up interviews. The intervention group was more satisfied with their bone health care compared to the usual care group at both their 12- and 52-week follow-ups (standardized effect size = 0.28 at 12-weeks and 0.17 at 52-weeks, p < 0.001). There were no differences between the intervention and usual care groups in QOL or OP knowledge at either time point.ConclusionsA tailored DXA result letter and bone-health educational brochure sent to patients improved patient satisfaction with bone-related health care.Trial registrationClinical Trials.gov Identifier: NCT01507662 First received: December 8, 2011.

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Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

Cited by 33 publications

References 31 publications

The effects of combined training on bone metabolic markers in postmenopausal women

The effects of combined training on bone metabolic markers in postmenopausal women

Association of serum vitamin D with osteosarcopenic obesity: Korea National Health and Nutrition Examination Survey 2008–2010

Effects of a DXA result letter on satisfaction, quality of life, and osteoporosis knowledge: a randomized controlled trial

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