Effects of a Lactobacillus salivarius Probiotic Intervention on Infection, Cold Symptom Duration and Severity, and Mucosal Immunity in Endurance Athletes

Gleeson, Michael; Bishop, Nicolette C.; Oliveira, Marta; McCauley, Tracey; Tauler, Pedro; Lawrence, Claire

doi:10.1123/ijsnem.22.4.235

Cited by 79 publications

(94 citation statements)

References 27 publications

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“…Evidence suggests that the immunomodulatory effects are likely strain-specific [4]. The purported anti-inflammatory effects of probiotics have received considerable attention in the athletic community [5].…”

Section: Introductionmentioning

confidence: 99%

Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise

Jäger¹,

Purpura²,

Stone

et al. 2016

Nutrients

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Probiotics have immunomodulatory effects. However, little is known about the potential benefit of probiotics on the inflammation subsequent to strenuous exercise. In a double-blind, randomized, placebo controlled, crossover design separated by a 21-day washout, 15 healthy resistance-trained men ingested an encapsulated probiotic Streptococcus (S.) thermophilus FP4 and Bifidobacterium (B.) breve BR03 at 5 bn live cells (AFU) concentration each, or a placebo, daily for 3 weeks prior to muscle-damaging exercise (ClinicalTrials.gov NCT02520583). Isometric strength, muscle soreness, range of motion and girth, and blood interleukin-6 (IL-6) and creatine kinase (CK) concentrations were measured from pre- to 72 h post-exercise. Statistical analysis was via mixed models and magnitude-based inference to the standardized difference. Probiotic supplementation resulted in an overall decrease in circulating IL-6, which was sustained to 48 h post-exercise. In addition, probiotic supplementation likely enhanced isometric average peak torque production at 24 to 72 h into the recovery period following exercise (probiotic–placebo point effect ±90% CI: 24 h, 11% ± 7%; 48 h, 12% ± 18%; 72 h, 8% ± 8%). Probiotics also likely moderately increased resting arm angle at 24 h (2.4% ± 2.0%) and 48 h (1.9% ± 1.9%) following exercise, but effects on soreness and flexed arm angle and CK were unclear. These data suggest that dietary supplementation with probiotic strains S. thermophilus FP4 and B. breve BR03 attenuates performance decrements and muscle tension in the days following muscle-damaging exercise.

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Section: Introductionmentioning

confidence: 99%

Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise

Jäger¹,

Purpura²,

Stone

et al. 2016

Nutrients

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show abstract

“…Probiotics have been described as alternatives to antibiotic growth promoters for poultry against oxidative stress, improving mucosal and general immunity and increase their performances (Gleeson et al, 2012). Stressful situations in poultry farms may increase the incidence of gastrointestinal disease, particularly of diarrhea during production period and are likely to cause increased susceptibility to infections in the upper respiratory tract in part to suppress the immune system leading to growth rate deficiencies (Manafi, 2015).…”

Section: Assessment Of a Probiotic Containing Bacillus Subtilis On Thmentioning

confidence: 99%

Assessment of a probiotic Containing Bacillus Subtilis on the Performance and Gut Health of Laying Japanese Quails (Coturnix Coturnix Japonica)

Manafi

Khalaji

Mahdi

2016

Rev. Bras. Cienc. Avic.

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Keywords Japanese quails, egg production, gut health, immune response. ABStRACtThe present study was carried out to determine the effects of the inclusion of a spore-forming probiotic (Bacillus subtilis) in laying Japanese quail diets as an alternative to growth-promoting antibiotics to help produce healthy eggs and meat. This experiment was conducted as a completely randomized design with three treatments (control, 0.05% bacitracin methylene disalicylate (BMD), or 0.1% Bacillus subtilis) of five replicates of 11 quails each. Feed intake and egg production were recorded daily on cage basis. Body weight was determined at the beginning and end of the trial (36 and 42 weeks). At the end of the experiment (42 weeks), antibodies against Newcastle disease and avian influenza, egg components, Haugh units, eggshell quality and breaking strength, blood parameters, cecal microbial population, villus length, and crypt depth were measured. The dietary inclusion of Bacillus subtilis and BMD significantly (p≤0.05) increased egg production and egg weight; however, eggshell thickness and breaking strength, Haugh units, and eggshell percentages were not affected. The dietary addition of both products significantly (p≤0.05) decreased plasma cholesterol levels and increased LDL levels, as well as antibody levels against Newcastle disease and avian influenza (p≤0.01). In birds fed Bacillus subtilis and BMD, crypt depth was reduced, but villus height and villus to crypt ratio were significantly increased (p≤0.001) compared with those fed the basal diet. Cecal coliforms, E. coli, and Salmonella counts were reduced (p≤0.01) in quails fed the diets containing Bacillus subtilis and BMD compared those quails fed the non-supplemented diet. The results of this study demonstrated that in absence of AGPs, the inclusion of a spore-forming probiotic partially improves the performance of laying quails.

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“…Some studies could not show any benefit of probiotics in prevention of incidence, duration, or severity of symptoms in adult individuals Gleeson et al, 2012;Tiollier et al, 2007;Winkler et al, 2005).…”

Section: Adults and The Elderlymentioning

confidence: 99%

Probiotics and Prebiotics for Prevention of Viral Respiratory Tract Infections

Ahanchian

Jafari

2016

Probiotics, Prebiotics, and Synbiotics

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Effects of a Lactobacillus salivarius Probiotic Intervention on Infection, Cold Symptom Duration and Severity, and Mucosal Immunity in Endurance Athletes

Cited by 79 publications

References 27 publications

Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise

Probiotic Streptococcus thermophilus FP4 and Bifidobacterium breve BR03 Supplementation Attenuates Performance and Range-of-Motion Decrements Following Muscle Damaging Exercise

Assessment of a probiotic Containing Bacillus Subtilis on the Performance and Gut Health of Laying Japanese Quails (Coturnix Coturnix Japonica)

Probiotics and Prebiotics for Prevention of Viral Respiratory Tract Infections

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