Effectiveness of preemptive analgesia on postoperative pain following third molar surgery: Review of literatures

Yamaguchi, Akira; Sano, Kiyoshi

doi:10.1016/j.jdsr.2013.07.002

Cited by 23 publications

(23 citation statements)

References 19 publications

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“…There are numerous techniques for analgesic treatment of postoperative pain, but the interest in recent years has been focused on the preemptive analgesia. This is due to the development of the fundamental sciences associated with the discovery of central sensitization by Woolf [20]. Neychev D et al stated that the use of preemptive analgesia with nimesulide results in significant reduction in the pain experience.…”

Section: Resultsmentioning

confidence: 99%

Knowledge and Awareness on the Usage of Preemptive Analgesics in Third Molar Extraction among Dental Students: A Survey

Balaji

Prabu

2020

JPRI

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Postoperative pain control after extraction of third molars is important for patients because of the effect of pain symptoms on the healing process and quality of life. The aim of this study was to assess the knowledge and awareness of dental students towards the use of preemptive analgesics in third molar extractions. A questionnaire based survey was conducted among 100 dental students. Questionnaire was distributed through a survey link. Results were collected and analysed using IBM SPSS Statistical Analyzer (23.0 version). Frequency distribution and descriptive analysis were carried out. The variables were analysed using Pearson Chi square test. P Value less than or equal to 0.05 was considered to be statistically significant. The results of the study showed that the knowledge and awareness of dental students about the usage of preemptive analgesics in day to day practice varied according to their year of study. Interns were observed to have more knowledge and awareness regarding preemptive analgesics in comparison to third years and final years. Preemptive analgesics play a significant role in the elimination of postoperative pain in patients after removal of third molars. Therefore, it is of utmost importance for dental students to gain sufficient knowledge regarding the usage and importance of preemptive analgesics in dentistry.

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Section: Resultsmentioning

confidence: 99%

Knowledge and Awareness on the Usage of Preemptive Analgesics in Third Molar Extraction among Dental Students: A Survey

Balaji

Prabu

2020

JPRI

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“…Estos resultados contrastan con el estudio realizado por Primosh y colaboradores (5) , quienes compararon los mismos fármacos no encontrando diferencias, lo cual podría haberse debido a que la dosis de los medicamentos no se calcularon en base a mg/kg de peso, tomándose en cuenta la edad de los niños participantes en el estudio; así como que la administración se dio en un intervalo menor al establecido de acuerdo al mecanismo de acción de los fármacos. Sin embargo en revisiones de estudios sobre profilaxis analgésica en terceras molares se concluye que ésta es un método más exitoso para suprimir el dolor posoperatorio ya que la administración prequirúrgica de un analgésico puede inhibir la sensibilización central por daño tisular (6,7,8) y que si ésta en algunos casos no es demostrada puede deberse a una subdosificación o no dosificación (9,10) , como lo demostrado por Milani en un estudio realizado con estos medicamentos (11) .…”

Section: Discussionunclassified

Efecto analgésico profiláctico del paracetamol e ibuprofeno en la extracción de piezas dentarias en niños

Torres¹,

Vadillo²

2019

Kiru

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“…Especially when the purpose is to collect different information (i.e., performance of meta‐analysis), the clear classification of data and results is mandatory. In the same field, Yamaguchi and Sano () suggest the effectiveness of preemptive analgesia in third‐molar surgery, reporting promising conclusive results derived from mixed unclassified studies. Similar findings were reported by Penprase, Brunetto, Dahmani, Forthoffer, and Kapoor () who concluded a positive effect of the preemptive use of NSAIDs.…”

Section: Discussionmentioning

confidence: 99%

“…Preclinical and clinical studies suggest that the use of different preoperative analgesic medications can be effective in inhibiting hypersensitization of nociceptors and, consequently, postoperative pain (Costa et al, ; Katz, Clarke, & Seltzer, ). However, there is still controversy regarding methodological aspects of the published clinical trials available, leading to confusion or misinterpretation (Brennan & Kehlet, ; Dahl & Møiniche, ; Møiniche, Kehlet, & Dahl, ; Yamaguchi & Sano, ). The aim of the present study was to evaluate the effectiveness of the preoperative administration of DEX under postoperative pain conditions via a systematic review and meta‐analysis.…”

Section: Introductionmentioning

confidence: 99%

Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta‐analysis

Esparza-Villalpando

Pozos‐Guillén

Masuoka

et al. 2017

Drug Development Research

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Post-Market Research Clinical evidence supports the use of dexketoprofen trometamol (DEX) to manage acute postoperative pain. However, controversies surround the impact of the use of this drug in preoperative analgesic protocols. The aim of the present meta-analysis was to evaluate the effectiveness of the preoperative administration of DEX under postoperative pain conditions. Electronic and manual searches were conducted through diverse electronic databases. A systematic review and meta-analysis to evaluate the analgesic efficacy of the preoperative administration of DEX was performed including Randomized Clinical Trials (RCTs) published between 2002 and 2017. Suitable individual studies were evaluated through a quality system, and the data were extracted and analyzed. Fourteen RTCs were included (12 parallel trials and 2 cross-over trials), published in the English and Turkish languages. Follow-up periods ranged from 4, 6, 8, 24, and 48 hr. All trials measured the outcome result as Acute Pain Level (APL) (VAS, NRS, VRS), time to requiring a second dose of DEX or analgesic emergency and consumption of opioids via patient-controlled analgesia. When the comparators were other drugs - paracetamol, Lornoxicam or placebo during the preoperative time, preoperative administration of DEX was superior. When the comparison comprised preoperative and postoperative DEX, both alternatives exhibited comparable analgesic effects. The analgesic efficacy of the preoperative administration of DEX when compared to placebo, lornoxicam, and paracetamol on postoperative pain was evident. Preoperative administration of DEX compared to its immediate postoperative administration showed a similar analgesic effect.

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Effectiveness of preemptive analgesia on postoperative pain following third molar surgery: Review of literatures

Cited by 23 publications

References 19 publications

Knowledge and Awareness on the Usage of Preemptive Analgesics in Third Molar Extraction among Dental Students: A Survey

Knowledge and Awareness on the Usage of Preemptive Analgesics in Third Molar Extraction among Dental Students: A Survey

Efecto analgésico profiláctico del paracetamol e ibuprofeno en la extracción de piezas dentarias en niños

Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta‐analysis

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