Effectiveness of Different Cleaning Agents against the Colonization of Candida spp and the in Vitro Detection of the Adherence of These Yeast Cells to Denture Acrylic Surfaces

Abstract

PurposeThe aim of this study is to examine the effect Klorhex and Fittydent, which are used as cleaning agents on the adhesion of Candida on the surfaces of acrylic denture and palatal mucosa. In addition, ability of yeasts to adhere to acrylic strips was evaluated after applying these agents in vitro.Materials and MethodsEach group of 15 patients cleaned their dentures with either Klorhex or with Fittydent. The control group cleaned their dentures with water.ResultsIt was found that 62.2% of the patients had colonies of Candida species on their palatal mucosa which was reduced to 51.1% after using these cleaning agents. The colonization rate with Candida spp on their dentures was reduces from 82.2% to 68.8% using these cleaning agents. The mean adhesion value of the Candida strains isolated from the acrylic strips were found to be 75 cell/strip prior to applying the Klorhex and Fittydent and 37.5 cell/strip and 15 cell/strip after applying these agents, respectively.ConclusionThese results showed that Klorhex and Fittydent have a certain preventive effect on the colonization rate of Candida spp on the surface of these dentures, the palatal mucosa, as well as on the acrylic strips in vitro.

Comparative effects of denture cleansers on physical properties of polyamide and polymethyl methacrylate base polymers

“…Denture cleansers are used to provide adequate denture plaque control, prevent halitosis, remove discoloring caused by foods and drinks, eliminate Candida albicans and Candida glabrata and other microorganisms, to dissolve calculus and prevent denture-induced stomatitis [3][4][5] . In patients, particularly those who are very old, have Alzheimer's disease, dementia or low motor capacity, the use of chemical agents may be the only means of denture hygiene 6,7) .…”

Antifungal activity of components used for decontamination of dental prostheses on the growth of Candida albicans

“…Chlorhexidne digluconate is an effective wide spectrum antimicrobial, which has a bacteriostatic effect due to its capacity to precipitate and coagulate the microbial cytoplasm via low molecular weight components, such as phosphorus and potassium 15,16 . However, continued use may cause staining and alterations of color in the acrylic 17 .…”

Proteti̇k Di̇ş Tedavi̇si̇nde Dezenfeksi̇yon Ve Steri̇li̇zasyon

“…52 Klorheksidinde bekletme iĢleminin protez kaide ve astar materyallerinin yüzey pürüzlülüğü üzerinde anlamlı bir etkisi olmadığı ve etkili bir dezenfeksiyon yöntemi olduğu belirtilmiĢtir. 53 Yapılan bir çalıĢmada sodyum hipoklorit ve klorheksidinle dezenfeksiyon iĢleminden sonra akrilik kaide ve akrilik ve silikon esaslı astar materyallerinin yüzey pürüzlülüğü ve sertliği değerlendirilmiĢ, bu materyallerin protez dezenfeksiyonunda güvenle kullanılabileceği belirtilmiĢtir.…”