Effectiveness of bee venom acupuncture in alleviating post-stroke shoulder pain: a systematic review and meta-analysis

Lim, Sung Min; Lee, Sook-Hyun

doi:10.1016/s2095-4964(15)60178-9

Cited by 34 publications

(31 citation statements)

References 12 publications

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“…A systematic review surveyed 138 potential articles, in which only four were randomized controlled trials that meeting the researchers’ criteria. The review demonstrated that injection with BV was more effective than injection with saline in decreasing poststroke shoulder pain [ 79 ].…”

Section: Clinical Applications and Mechanism Of Bv Injectionmentioning

confidence: 99%

Clinical Applications of Bee Venom Acupoint Injection

Lin

Hsieh

2020

Toxins

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Bee venom is a complex natural mixture with various pharmaceutical properties. Among these properties, its peptides and enzymes have potential medical therapy for pain relief and inflammation. In clinical settings, this therapy has been used widely to treat diseases by injecting into acupoints. In this article, we have conducted various research from PubMed, Cochrane Library, and Clinical Key from inception of July 2020. The results revealed that bee venom therapy has been reported effective in anti-inflammatory, antiapoptosis, and analgesic effects. Moreover, bee venom acupuncture has been commonly used for clinical disorders such as Parkinson disease, neuropathic pain, Alzheimer disease, intervertebral disc disease, spinal cord injury, musculoskeletal pain, arthritis, multiple sclerosis, skin disease and cancer.

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Section: Clinical Applications and Mechanism Of Bv Injectionmentioning

confidence: 99%

Clinical Applications of Bee Venom Acupoint Injection

Lin

Hsieh

2020

Toxins

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“…In a previous study, an injection of a high dose of BV (2.5 mg/kg) into an acupoint induced a motor function deficit at 60 and 120 min [ 6 ], as well as skin hypersensitivity; adverse effects such as itching, but not severe effects such as an anaphylactic reaction, have been documented [ 27 , 28 ]. These side effects were not observed in this study.…”

Section: Discussionmentioning

confidence: 99%

Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I)

Lee

Kim

et al. 2017

Toxins

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Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases accompanying pain. However, the analgesic effect of BV in a CPIP model remains unknown. The application of a tight-fitting O-ring around the left ankle for a period of 3 h generated CPIP in C57/Bl6 male adult mice. BV (1 mg/kg; 1, 2, and 3 times) was administered into the SC layer of the hind paw, and the antiallodynic effects were investigated using the von Frey test and by measuring the expression of neurokinin type 1 (NK-1) receptors in dorsal root ganglia (DRG). The administration of BV dose-dependently reduced the pain withdrawal threshold to mechanical stimuli compared with the pre-administration value and with that of the control group. After the development of the CPIP model, the expression of NK-1 receptors in DRG increased and then decreased following the administration of BV. SC administration of BV results in the attenuation of allodynia in a mouse model of CPIP. The antiallodynic effect was objectively proven through a reduction in the increased expression of NK-1 receptors in DRG.

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“…In Tabelle 1 sind bisher nachgewiesene Inhaltsstoffe des Bienengifts zusammengestellt. In einer systematischen Überprüfung und Metaanalyse von Lim und Lee [14] zur Effektivität der Bienengiftakupunktur bei Schulterschmerzen nach einem Schlaganfall wurden 9 Datenbanken (MED-LINE, EMBASE, Cochrane Library, CNKI, J-STAGE sowie 4 koreanische medizinische Datenbanken) durchsucht. Von 138 potenziell relevanten Arbeiten erfüllten 4 randomisierte, kontrollierte Studien die Einschlusskriterien; die Bienengiftakupunktur wurde entweder als alleinige Therapie oder als Ergänzung zu üblichen Behandlungen bei Schulterschmerzen nach Schlaganfall mit einer jeweiligen Kontrollgruppe verglichen.…”

Section: Biochemische Zusammensetzung Des Bienengiftsunclassified

Bienengift in der Komplementärmedizin

Hainbuch¹

2016

Zeitschrift für Komplementärmedizin

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Summary Bienenprodukte wurden bereits in der Antike medizinisch genutzt. Seit einigen Jahrzehnten r?ckt besonders die Anwendung von Honig wieder in den Fokus der medizinischen Forschung, u.a. wegen seiner antibakteriellen und antimikrobiellen Wirkung z. B. bei der Wundheilung oder hinsichtlich seines m?glichen Potenzials bei der Bek?mpfung multiresistenter Bakterienst?mme. Der Begriff ?Apitherapie? umfasst jedoch mehr als den Einsatz von Medizinalhonig. Apitherapie beinhaltet die medizinische Anwendung aller Bienenprodukte wie Honig, Propolis, Pollen, Bienenbrot, Bienengift, Bienenwachs, Gel?e royale, Apilarnil und Bienenstockluft. Der Artikel nimmt die medizinische Anwendung von Bienengift in den Fokus.

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Effectiveness of bee venom acupuncture in alleviating post-stroke shoulder pain: a systematic review and meta-analysis

Cited by 34 publications

References 12 publications

Clinical Applications of Bee Venom Acupoint Injection

Clinical Applications of Bee Venom Acupoint Injection

Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I)

Bienengift in der Komplementärmedizin

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