Effectiveness of adjunctive interventions for accelerating orthodontic tooth movement: a systematic review of systematic reviews

Abstract

This study was aimed to summarise published systematic reviews (SRs) that assess the effects of adjunctive interventions on the acceleration of orthodontic tooth movement (OTM). Electronic and manual searches were performed up to August 2016. Systematic reviews investigating the impact of adjunctive techniques on the promotion of OTM were included. The methodological quality of the included reviews was evaluated using the A Measurement Tool to Assess Systematic Reviews (AMSTAR) scale. The quality of evidence for each intervention was assessed using GRADE. The Jadad decision algorithm was used to select a study to provide body evidence from discordant reviews on the same intervention. A total of 11 SRs were included in this study. AMSTAR scores ranged from 4 to 10 of 11. The quality of evidence ranged from very low to low. The short-term (1-3 months) effects of low-level laser therapy (LLLT, 5 and 8 J cm ) and corticotomy were supported by low-quality evidence. The evidence regarding the efficacy of photobiomodulation, pulsed electromagnetic field, interseptal bone reduction, two vibrational devices (Tooth Masseuse and Orthoaccel) and electrical current was of very low quality. Relaxin injections and extracorporeal shock waves were reported to have no impact on OTM according to low- and very low-quality evidence, respectively. Based on currently available information, we conclude that low-quality evidence indicates that LLLT (5 and 8 J cm ) and corticotomy are effective to promote OTM in the short term. Future high-quality trials are required to determine the optimal protocols, as well as the long-term effects of LLLT and corticotomy, before warranting recommendations for orthodontics clinics.

Effect of platelet-rich plasma on the rate of orthodontic tooth movement:

“…4,10,[25][26][27] Injections were delivered every 3 weeks and repeated until the sixth week following the protocol reported by Rashid et al 5 Although the study continued for 4 months, injections were not continued through the whole duration of the study in order to determine whether PRP injections were enough in the initial phases of tooth movement only, as compared with corticotomy 12 or low-level laser therapy applications. 3 The results of the current study showed a faster rate of canine retraction on the intervention side in the first month by 15% and in the second month by 5%. Despite this increase being statistically significant in the first month (P ¼ .049) and nonsignificant in the second month (P ¼ .772), the results reflected a positive correlation between PRP injection and acceleration of orthodontic tooth movement.…”

“…Although each approach has claimed to be superior to the others in different studies, conflicting evidence concerning each technique still exists. 2,3 Pharmacologic approaches to accelerate the rate of orthodontic tooth movement have been investigated in humans since the 1980s. 4 If proven clinically efficient, pharmacologic approaches might surpass other approaches as they are less invasive, less costly, and more controlled.…”

Efficiency of low-level laser therapy for orthodontic tooth movement: a review

“…Finding the latter would be of great importance to determine future clinical guidelines. Before drawing conclusions for orthodontic clinics, highquality trials are required to conclude about the long-term effects of LLLT and to give the optimal protocols [36]. …”

Absorption Capability of a 645-nm Diode Laser on Swine Soft Tissue Samples: a Preliminary Study in an Ex-Vivo Model Tissue Samples: a Preliminary Study in an Ex-Vivo Mo

“…The post-extraction sockets 18,19 (even if a first intention closure is performed), periodontal surgery and implantology 20 , orthodontics 21,22 , temporomandibular joints disorders, and neurological conditions may all benefit from superficial irradiation in which part of the laser beam penetrates a deeper level 23,24 .…”