Effect on electrospun fibres by synthesis of high branching polylactic acid

Abstract

Polylactic electrospun porous fibres have been widely used in tissue engineering scaffolds. However, the application of linear polylactic is limited due to its poor hydrophilicity, which leads to phase separation and has been seldom used in porous fibre preparation. Instead, branching polylactic acts as a new effective method to prepare porous fibres because it can increase polylactic polar property and make it easy to be formulated in the following application. In the current study, we prepared an ultra-high molecular weight of high branching polylactic with glycerol as the initiator by controlling the ring-opening polymerization time, adding amount of catalyst and glycerol. The structure, molecular weight and thermal properties of copolymers were tested subsequently. The result showed that the surface of the high branching polylactic films is smooth, hydrophilic and porous. This branching polylactic formed electrospun porous fibres and possessed a strong adsorption of silver ion. Our study provided a simple and efficient way to synthesize branching polylactic polymer and prepare electrospun porous fibres, which may provide potential applications in the field of biomaterials for tissue engineering or antibacterial dressing compared with the application of linear polylactic and 3-arm polylactic materials.

Shape-Memory Properties of 3D Printed Cubes from Diverse PLA Materials with Different Post-Treatments

“…1639 cm −1 -(C=C) stretching vibrations due to thermal decomposition [32,33] 5. 1451 cm −1 -CH3 (methyl) asymmetric deformations [31,34,35] 6. 1385 cm −1 + 1359 cm −1 --CH-symmetric and asymmetric bending [31] 7.…”

Preparation and Characterization of Electrospun Polylactic Acid (PLA) Fiber Loaded with Birch Bark Triterpene Extract for Wound Dressing

“…To fabricate eletrospun fibers, PLA can be found to dissolve in single (24)(25)(26), binary (27)(28)(29), or ternary (12)…”

“…Chloroform and DCM are the most frequently used solvents. They can be used alone (24,25) or mixed with other solvents, such as ethanol (27), tetrahydrofuran (28), and dimethylformamide (29). In this study, the raw PLA can be dissolved in chloroform, DCM, or hexafluoroisopropanol (HFIP).…”

Synthesis of Ultrahigh Molecular Weight PLAs Using a Phenoxy-Imine Al(III) Complex

“…Although many papers on the synthesis of PLLA have been published, there is a serious lack of findings focusing on the synthesis of UHMWPLLA. 13 , 21 , 23 , 24 The present literature mainly focuses on the synthesis of relatively low molecular weights (in the order of 10 3 –10 5 g/mol); while only limited works tackle the synthesis of ultrahigh molecular weight (UHMW) PLA. The common synthetic strategy to achieve high/ultrahigh molecular weights is by solid-state polymerization or by the use of multiols as initiators for the ROP catalysts resulting in highly branched PLAs.…”