Effect of zinc oxide nanoparticles on the<i>in vitro</i>degradation of electrospun polycaprolactone membranes in simulated body fluid

Augustine, Robin; Kalarikkal, Nandakumar; Thomas, Sabu

doi:10.1080/00914037.2015.1055628

Cited by 86 publications

(65 citation statements)

References 48 publications

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“…PCl and PCL/ZnO NCs irradiated at 25 kGy exhibited marginal variations in the melting point temperature. The temperature of crystallization for films before exposure to gamma irradiation increased with the addition of 0.5% and 1% of NPs, revealing that NPs, in low concentration, had a nucleating effect on the PCL 17 . Irradiated PCL/ZnO NCs films had a small decrease in the temperature needed for crystallization when compared to the irradiated PCL film.…”

Section: Differential Scanning Calorimetrymentioning

confidence: 98%

“…The increase in the melting point temperature for NCs with a low NPs concentration may be due to the formation of thick crystals, shifting the melting point to a higher temperature [17] . Nevertheless, the addition of more than 1% of NPs produced agglomerates, which hindered the crystallization of polymer, producing crystals with a thinner lamellar, decreasing the melting point temperature, corroborating with the results obtained by Augustine and co-workers [17] . PCl and PCL/ZnO NCs irradiated at 25 kGy exhibited marginal variations in the melting point temperature.…”

Section: Differential Scanning Calorimetrymentioning

confidence: 99%

“…ZnO is a biocompatible inorganic agent, semiconductor with a band-gap in the UV region, which makes it an efficient absorber of UV radiation [16] . When added to polymeric matrices, the nanocomposites (NCs) exhibit antibacterial activity, low toxicity, lower the gas permeability, gener-reactive oxygen species, cell adhesion and proliferation [12,17] . The particles with nanometric dimensions have a strong tendency to agglomerate due to high surface energy, which acts to prevent their dispersion in the polymer matrix, compromising the properties expected for the material [18] .…”

Section: Introductionmentioning

confidence: 99%

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Gamma irradiation effects on polycaprolactone/zinc oxide nanocomposite films

et al. 2019

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Polycaprolactone (PCL) to which has been added zinc oxide nanoparticles (ZnO NPs) produces nanocomposites (PCL/ZnO NCs). These nanocomposites can be used in biomedical applications and in the food packaging sector. However, for these materials to be used in these applications, they need to be sterilized. For this, gamma irradiation is the most common method. Thus it is important to evaluate the effects of gamma irradiation on the properties of PCL and PCL/ZnO that have been exposed to gamma irradiation. PCL/ZnO NCs films were obtained by solvent casting and exposed to gamma irradiation at 25 kGy and evaluated by Fourier transform infrared spectra (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) scanning electron microscopy (SEM) and mechanical properties. Mechanical properties and crystallinity showed marginal variations for the irradiated samples. The results obtained demonstrate that gamma irradiation at 25 kGy, did not cause profound changes in nanocomposite properties.

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Section: Differential Scanning Calorimetrymentioning

confidence: 98%

Section: Differential Scanning Calorimetrymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Gamma irradiation effects on polycaprolactone/zinc oxide nanocomposite films

et al. 2019

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“…It has been commented that the electrospinning technique is an ideal strategy for constructing superhydrophobic surfaces on a large scale, being an increasingly hot research topic for a wide number of industrial applications [74]. In addition, the presence of ZnO NPs into the electrospun fibres can offer an additional multifunctionality as an efficient corrosion inhibitor and even additional advantages such as antibacterial properties, nontoxicity and anticancer behaviour [75].…”

Section: Electrospun Protective Self-healing Coatingsmentioning

confidence: 99%

Electrospinning: A Powerful Tool to Improve the Corrosion Resistance of Metallic Surfaces Using Nanofibrous Coatings

Rivero

Redin

Rodríguez

2020

Metals

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The use of surface engineering techniques to tune-up the composition of nanostructured thin-films for developing functional coatings with advanced properties is a hot topic within the scientific community. The control of the coating structure at the nanoscale level allows improving the intrinsic properties of the surface compared to bulk materials. A nanodeposition technique with increasing popularity in the field of nanotechnology is electrospinning. This technique permits the fabrication of long and continuous fibres on the micro-nano scale. The good control over fibre morphology combined with its simplicity, cost-effectiveness, easy exploitability and scalability make electrospinning a very interesting tool for technological applications. This review is focused on the use of the electrospinning technique to protect metallic surfaces against corrosion. Polymeric precursors, from natural or biodegradable to synthetic polymers and copolymers can be electrospun with an adequate control of the operational deposition parameters (applied voltage, flow rate, distance tip to collector) and the intrinsic properties of the polymeric precursor (concentration, viscosity, solvent). The electrospun fibres can be used as an efficient alternative to encapsulate corrosion inhibitors of different nature (inorganic or organic) as well as self-healing agents which can be released to reduce the corrosion rate in the metallic surfaces.

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“…PCL membranes imparted antibacterial property to the scaffolds (Augustine et al, 2014c). The fabricated PCL/ZnO nanocomposite membranes have shown enhanced biodegradation than the neat PCL membranes (Augustine et al, 2016a).…”

Section: Incorporation Of Zno Nanoparticles In Electrospunmentioning

confidence: 93%

Microbial Barrier Property and Blood Compatibility Studies of Electrospun Poly-ƹ-Caprolactone/ Zinc Oxide Nanocomposite Scaffolds

Augustine¹,

Kalarikkal²,

Thomas³

2017

J. Sib. Fed. Univ., Biol.

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Electrospun poly-ƹ-caprolactone/zinc oxide (PCL/ZnO) nanocomposite scaffolds were reported for tissue engineering and wound healing applications. Wound coverage materials should have good barrier property against invading microbes. Since wound coverage materials and tissue engineering scaffolds are in direct contact with blood, such materials should be blood compatible. Thus, blood compatibility of the fabricated scaffolds has been tested by RBC and WBC aggregation studies. Hemolysis assay and platelet activation study were also carried out. This study is promising in the sense that the fabricated scaffolds showed excellent microbial barrier property and were highly compatible with RBC and WBC and did not induce haemolysis. However, need to be vigilant regarding the possible platelet aggregation that can happen at higher concentrations of ZnO nanoparticles.

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Effect of zinc oxide nanoparticles on thein vitrodegradation of electrospun polycaprolactone membranes in simulated body fluid

Cited by 86 publications

References 48 publications

Gamma irradiation effects on polycaprolactone/zinc oxide nanocomposite films

Gamma irradiation effects on polycaprolactone/zinc oxide nanocomposite films

Electrospinning: A Powerful Tool to Improve the Corrosion Resistance of Metallic Surfaces Using Nanofibrous Coatings

Microbial Barrier Property and Blood Compatibility Studies of Electrospun Poly-ƹ-Caprolactone/ Zinc Oxide Nanocomposite Scaffolds

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