Effect of yeast cell product (CitriStim) supplementation on turkey performance and intestinal immune cell parameters during an experimental lipopolysaccharide injection

Shanmugasundaram, R.; Sifri, Mamduh; Jeyabalan, Ramesh; Selvaraj, Ramesh K.

doi:10.3382/ps.2014-04174

Cited by 13 publications

(8 citation statements)

References 32 publications

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“…However, this study shows β-glucan supplementation could decrease the ileal gene expression level of TLR-5 compared to anthocyanin-fed birds. Sheoran et al [63] explained reduced TLR-5 mRNA expression with the decreasing colonization of pathogens and Shanmugasundaram et al [64] reported whole yeast cell product supplementation could influence the growth of beneficial bacteria, such as Lactobacillus and Bifidobacterium. Therefore, downregulation of TLR-5 mRNA level in β-glucan treatment could have been due to the same fact in this study.…”

Section: Discussionmentioning

confidence: 99%

Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged with Escherichia coli Lipopolysaccharide

Csernus

Bíró

Babinszky

et al. 2020

Animals

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This study was conducted to investigate the effect of carotenoid, oligosaccharide and anthocyanin supplementation in broiler diets under Escherichia coli lipopolysaccharide (LPS) challenge. Ross 308 chickens were fed 5 diets: basal diet (control diet), diet supplemented with β-glucan in 0.05% (positive control) and diets with 0.5% carotenoid-, oligosaccharide- or anthocyanin contents. On the 26th days of age, chickens were challenged intraperitoneally 2 mg LPS per kg of body weight. 12 h after injection, birds were euthanized, then spleen and ileum samples were collected. LPS induced increased relative mRNA expression of splenic (p = 0.0445) and ileal (p = 0.0435) interleukin-1β (IL-1β), which was lower in the spleen in carotenoid (p = 0.0114), oligosaccharide (p = 0.0497) and anthocyanin (p = 0.0303)-treated chickens compared to LPS-injected control birds. Dietary supplementation of carotenoids also decreased relative gene expression of splenic interleukin-6 (IL-6) (p = 0.0325). In the ileum, β-glucan supplementation showed lower relative mRNA expression of toll-like receptor 5 (TLR-5) (p = 0.0387) compared to anthocyanin treatment. Gene expression of both splenic and ileal interferon-α (IFN-α), interferon-γ (IFN-γ), toll-like receptor 4 (TLR-4) and toll-like receptor 5 (TLR-5) were not influenced by dietary supplements. In conclusion, carotenoids, oligosaccharides and anthocyanins could partially mitigate the immune stress caused by LPS challenge. All of the compounds impacted longer villus height (p < 0.0001), villus height:crypt depth ratios were higher after β-glucan (p < 0.0001) and anthocyanin (p = 0.0063) supplementations and thickened mucosa was observed in β-glucan (p < 0.0001), oligosaccharide (p < 0.0001) and anthocyanin (p = 0.048) treatments. All of these findings could represent a more effective absorption of nutrients.

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Section: Discussionmentioning

confidence: 99%

Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged with Escherichia coli Lipopolysaccharide

Csernus

Bíró

Babinszky

et al. 2020

Animals

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“…Previous studies in broilers revealed that LPS challenge compromised growth performance (Korver and Klasing 1997;Li et al 2015), impaired both innate and adaptive immunity (Korver and Klasing 1997), and induced intestinal inflammation coupled with a damage of intestinal structure and barrier function as evidenced by the destructive intestinal morphology and tight junctions (Hu et al 2011;Jiang et al 2015;Li et al 2015). Yeast oligosaccharide had been shown to improve performance (Morales-Lopez and Brufau 2013) and to modulate systemic and intestinal immune responses in LPS-challenged broilers (Morales-Lopez and Brufau 2013; Shanmugasundaram et al 2014). However, it is unknown whether LY addition can protect the immune responses and intestinal structure against LPS challenge in broilers.…”

Section: Introductionmentioning

confidence: 99%

Effects of live yeast on immune responses and intestinal morphological structure in lipopolysaccharide (LPS)-challenged broilers

Wang¹,

Ren²,

Li³

et al. 2016

Can. J. Anim. Sci.

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The effects of live yeast (LY) on immune responses and intestinal morphological structure in lipopolysaccharide (LPS) challenged broilers were investigated. A total of 480 one-day-old male broilers were divided into six groups following a 3 × 2 factorial arrangement (eight replicates) with three dietary LY dosages (0%, 0.05%, or 0.50%) and two immune treatments (injection of saline or LPS) given at an interval of 48 h between 21 and 27 d of age. Blood was sampled on days 21 and 27, while intestine were collected on day 28. Results showed that LPS damaged (P ≤ 0.05) intestinal histomorphology, and tended to reduce (P = 0.071) serum anti-Newcastle disease virus (NDV) titers on day 21, but increase (P = 0.089) jejunal maltase activity. Supplemental LY at 0.05% elevated (P ≤ 0.05) ileal villus width and villus surface area, and serum anti-NDV titers on day 21. The addition at 0.50% increased (P ≤ 0.05) jejunal and ileal villus height to crypt depth ratio, reduced (P ≤ 0.05) jejunal maltase activity and crypt depth, and attenuated (P ≤ 0.05) LPS-induced increase (P ≤ 0.05) in serum diamine oxidase activity on day 21. Collectively, supplemental LY at 0.05% improved antibody response and the addition at 0.50% alleviated LPS-induced intestinal damage in broilers.

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“…First of all, some researches have proved that yeast wall polysaccharides could improve intestinal microbiota. It has been reported that the Pichia guilliermondii cell polysaccharides significantly decreased the number of pathogenic in the intestinal of chickens [35]. Zhang et al found that yeast polysaccharide could decreased the rate of diarrhea in weaned piglets, caused by the number of Escherichia coli and Salmonella in the caecum of weanling piglets which was significantly reduced by yeast polysaccharide [36].…”

Section: Discussionmentioning

confidence: 97%

Effect of Marine Red Yeast Rhodosporidium paludigenum on Diarrhea Rate, Serum Antioxidant Competence, Intestinal Immune Capacity, and Microflora Structure in Early-Weaned Lambs

Liu

Zhang

et al. 2022

BioMed Research International

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In this study, the influences of marine red yeast Rhodosporidium paludigenum (MRYP) on diarrhea rate, serum antioxidant capacity, intestinal immunity capacity, and microflora structure of early-weaned lamb were investigated in a 60-day feeding trial. A total of 96 early-weaned lambs were utilized in this study. The lambs were divided into four experimental groups based on the percentage of marine red yeast Rhodosporidium paludigenum (MRYP) as milk replacer supplement. The rates of milk replacer supplement for the four groups were 0, 0.1%, 0.3%, and 0.5% of marine red yeast Rhodosporidium paludigenum (MRYP), respectively. The study was continued for 30 days. The results showed that (1) compared with control group, 0.5% marine red yeast Rhodosporidium paludigenum (MRYP) supplementation caused significantly decreases in average fecal score and diarrhea frequency by 33.74% and 40.23% ( P < 0.05 ). (2) No significant difference was found in all tested related antioxidant indexes in serum of four treatments ( P > 0.05 ). (3) The concentrations of SIgA, IgG, and IL-10 of group IV was significantly increased by 17.78%, 18.27%, and 8.17%, but the IL-6 and TNF-α were significantly decreased by 21.20% and 31.80%, compared to group I in the colon ( P < 0.05 ). (4) The number of Bifidobacterial and Lactobacilli of group IV was significantly increased by 14.87% and 15.09%, but Escherichia coli and Salmonella were significantly decreased by 20.19% and 10.15%, compared to group I in the colon ( P < 0.05 ). (5) A portion of marine red yeast Rhodosporidium paludigenum (MRYP) survived in the intestine of early-weaned lamb, and the number of survival marine red yeast Rhodosporidium paludigenum (MRYP) increased as the addition of marine red yeast Rhodosporidium paludigenum (MRYP) increased from 0.1 to 0.5% in milk replacer. Therefore, marine red yeast Rhodosporidium paludigenum (MRYP) has a potential to be a replacer of antibiotics for prevention and treatment of diarrhea in early-weaned lambs.

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Effect of yeast cell product (CitriStim) supplementation on turkey performance and intestinal immune cell parameters during an experimental lipopolysaccharide injection

Cited by 13 publications

References 32 publications

Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged with Escherichia coli Lipopolysaccharide

Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged with Escherichia coli Lipopolysaccharide

Effects of live yeast on immune responses and intestinal morphological structure in lipopolysaccharide (LPS)-challenged broilers

Effect of Marine Red Yeast Rhodosporidium paludigenum on Diarrhea Rate, Serum Antioxidant Competence, Intestinal Immune Capacity, and Microflora Structure in Early-Weaned Lambs

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