Effect of vitamin A supplementation in women of reproductive age on maternal survival in Ghana (ObaapaVitA): a cluster-randomised, placebo-controlled trial

Kirkwood, Betty; Hurt, Lisa; Amenga‐Etego, Seeba; Tawiah, Charlotte; Zandoh, Charles; Danso, Samuel; Hurt, Chris; Edmond, Karen; Hill, Zelee; Asbroek, Guus ten; Fenty, Justin; Owusu‐Agyei, Seth; Campbell, Oona M. R.; Arthur, Paul

doi:10.1016/s0140-6736(10)60311-x

Cited by 105 publications

(108 citation statements)

References 24 publications

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“…1), as were the sociodemographic characteristics that were investigated. 7 The 207 781 women who were recruited contributed 680 970 woman-years of follow-up and 3136 deaths. Although migration in and out of the study area was high, each woman enrolled was followed up for a mean of 3.3 years.…”

Section: Resultsmentioning

confidence: 99%

“…The general methods employed in the trial have been published elsewhere 7 and the protocol is available online. 12 The analysis plan, which was approved by an ad hoc data monitoring and ethics committee before the interim analysis of the trial results in June 2006, included a description of a series of planned secondary analyses.…”

Section: Methodsmentioning

confidence: 99%

“…4 However, trials in which women have been given vitamin A supplements during pregnancy 5 and in the postpartum period 6 have shown no effect on mortality. Prior to the ObaapaVitA trial in Ghana, 7 the published data on the effect of vitamin A supplementation among all women of reproductive age came from a single trial in Nepal. 8 In the Nepalese study, which was known as the Nepal Nutrition Intervention Project Sarlahi-2 (NNIPS-2) trial, pregnancyrelated mortality was found to be 40% (95% confidence interval, CI: 3-63) lower in the vitamin A arm than in the placebo arm.…”

Section: Introductionmentioning

confidence: 99%

“…7 In this paper, we present the results of a secondary analysis of the effect of weekly vitamin A supplementation on cause-specific mortality in the ObaapaVitA trial. This appears to be the first time that such data from a low-income country have been published.…”

Section: Introductionmentioning

confidence: 99%

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Effect of vitamin A supplementation on cause-specific mortality in women of reproductive age in Ghana: a secondary analysis from the ObaapaVitA trial

Hurt

Asbroek²,

Amenga‐Etego

et al. 2012

Bull. World Health Organ.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of vitamin A supplementation on cause-specific mortality in women of reproductive age in Ghana: a secondary analysis from the ObaapaVitA trial

Hurt

Asbroek²,

Amenga‐Etego

et al. 2012

Bull. World Health Organ.

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“…The research was undertaken within seven contiguous districts of the Brong Ahafo region of Ghana between January 2008 and July 2009, nested within two consecutive trials addressing maternal [1] and neonatal health and survival [2]. Women were screened once at pregnancy (over 20,000 women), and again between 4 and 12 weeks after birth (close to 14,000) with the locally validated Patient Health Questionnaire (PHQ-9) [3].…”

Section: Introductionmentioning

confidence: 99%

Contribution of the Depression in ObaapaVitA and Newhints (DON) Population-based Cohort Study towards Perinatal Depression Epidemiologythe Ghana Model

Weobong¹,

Kirkwood²

2015

J Depress Anxiety

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, or developing workable interventions from scratch. It will also be apt to add value to these interventions by incorporating other interventions that promote child growth and development, which is beginning to gain considerable currency as a public health issue requiring immediate attention. The benefits from such integrated interventions are huge, guaranteeing optimal child development and growth, school readiness, optimal adolescent growth and health, and ultimately a productive and healthy adult population. ConclusionThe stage has been set for testing psychological treatments and behavioral interventions in this setting. The critical evidence on the burden, determinants, and consequences of perinatal depression, supporting the need for interventions was made entirely possible through healthy collaborations with maternal and child health initiatives. The Ghana model has provided a clear demonstration of how to merge mental health with other health interventions and the huge benefits that accrue to both. Journal of Depression and AnxietyJo urna l o f D e pr essio n a n d A nxiety ISSN: 2167-1044Citation: Weobong B, Kirkwood BR (2015) Contribution of the Depression in ObaapaVitA and Newhints (DON) Population-based Cohort Study towards Perinatal Depression Epidemiology-the Ghana Model.

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Effects of Vitamin A or Beta Carotene Supplementation on Pregnancy-Related Mortality and Infant Mortality in Rural Bangladesh

West¹,

Christian²,

Labrique³

et al. 2011

JAMA

124

133

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Effect of vitamin A supplementation in women of reproductive age on maternal survival in Ghana (ObaapaVitA): a cluster-randomised, placebo-controlled trial

Cited by 105 publications

References 24 publications

Effect of vitamin A supplementation on cause-specific mortality in women of reproductive age in Ghana: a secondary analysis from the ObaapaVitA trial

Effect of vitamin A supplementation on cause-specific mortality in women of reproductive age in Ghana: a secondary analysis from the ObaapaVitA trial

Contribution of the Depression in ObaapaVitA and Newhints (DON) Population-based Cohort Study towards Perinatal Depression Epidemiologythe Ghana Model

Effects of Vitamin A or Beta Carotene Supplementation on Pregnancy-Related Mortality and Infant Mortality in Rural Bangladesh

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