Effect of vegetable oils on obtaining lipid nanocarriers for sea buckthorn extract encapsulation

Manea, Adrian; Ungureanu, Camelia; Meghea, Aurelia

doi:10.1016/j.crci.2013.10.020

Cited by 22 publications

(11 citation statements)

References 29 publications

(30 reference statements)

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“…It is used as auxiliary product in treatment of frostbites and skin damage [54, 66] resulting from exposure to UV radiation, x-rays and chemical compounds [4, 38, 78]. Sea-buckthorn oil stimulates wound healing (including necrotic wounds), stimulating regeneration and processes of forming new healthy epidermis, and moreover collagen synthesis [81]. This oil reduces bedsores, treats eczema and reduces spots, acne, allergic and inflammatory lesions of the skin [40, 58, 66].…”

Section: Sea-buckthorn Oil In Cosmetic Productsmentioning

confidence: 99%

Abundance of active ingredients in sea-buckthorn oil

2017

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Vegetable oils are obtained by mechanical extraction or cold pressing of various parts of plants, most often: seeds, fruits, and drupels. Chemically, these oils are compounds of the ester-linked glycerol and higher fatty acids with long aliphatic chain hydrocarbons (min. C14:0). Vegetable oils have a variety of properties, depending on their percentage of saturation. This article describes sea-buckthorn oil, which is extracted from the well characterized fruit and seeds of sea buckthorn. The plant has a large number of active ingredients the properties of which are successfully used in the cosmetic industry and in medicine. Valuable substances contained in sea-buckthorn oil play an important role in the proper functioning of the human body and give skin a beautiful and healthy appearance. A balanced composition of fatty acids give the number of vitamins or their range in this oil and explains its frequent use in cosmetic products for the care of dry, flaky or rapidly aging skin. Moreover, its unique unsaturated fatty acids, such as palmitooleic acid (omega-7) and gamma-linolenic acid (omega-6), give sea-buckthorn oil skin regeneration and repair properties. Sea-buckthorn oil also improves blood circulation, facilitates oxygenation of the skin, removes excess toxins from the body and easily penetrates through the epidermis. Because inside the skin the gamma-linolenic acid is converted to prostaglandins, sea-buckthorn oil protects against infections, prevents allergies, eliminates inflammation and inhibits the aging process. With close to 200 properties, sea-buckthorn oil is a valuable addition to health and beauty products.

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Section: Sea-buckthorn Oil In Cosmetic Productsmentioning

confidence: 99%

Abundance of active ingredients in sea-buckthorn oil

2017

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“…Hot high-shear stirring is another versatile method for production of nanoparticles that requires short processing time. In the study conducted by García-Betanzos, Hernández-Sánchez, Bernal-Couoh, Quintanar-Guerrero, and de la Luz Zambrano-Zaragoza (2017), candeuba wax-based (a mixture of CRW and CLW) SLNs, and in works of Manea, Ungureanu, et al (2014) and Lacatusu et al (2013), and NLC based on cetyl palmitate and CRW were prepared by high-shear homogenization technique (García-Betanzos et al, 2017;Manea, Ungureanu, et al, 2014). Moreover, Campos, Madureira, Sarmento, Gomes, and Pintado (2015) and Madureira et al (2015) employed hot melt ultrasonication as the production method of CRW-SLNs.…”

Section: Preparation Processmentioning

confidence: 99%

“…The evaluation of in vitro antioxidant properties demonstrated the increased activity of all NLCs-GTE samples compared with that of native GTE. Antibacterial activity of NLCs-GTE systems varied depending on the oil type and GTE concentration (Manea, Ungureanu, et al, 2014). Mitrea et al (2014) also developed plant extract loaded NLCs formulated with either CRW or BW.…”

Section: Application In Food Industrymentioning

confidence: 99%

“…Liquid lipids or oils are specifically used for production of NLCs and provide imperfections in the solid matrix that can accommodate the drugs molecules (Shah et al., 2015). Natural edible oils such as pomegranate seed oil (PSO; Soleimanian, Goli, Varshosaz, & Maestrelli, 2018; Soleimanian, Goli, Varshosaz, & Sahafi, 2018), grape seed oil (Lacatusu, Badea, Stan, & Meghea, 2012; Lacatusu, Badea, Ovidiu, Bojin, & Meghea, 2012; Manea, Ungureanu, & Meghea, 2014), squalene (Lacatusu, Badea, Ovidiu, et al., 2012; Lacatusu, Badea, Stan, et al., 2012), sea buckthorn oil and St. John's wort oil (Manea, Ungureanu, et al., 2014), fish oil (Lacatusu, Badea, Stan, et al., 2012; Lacatusu et al., 2013), raspberry oil, and rice oil (Mitrea et al., 2014; Okonogi & Riangjanapatee, 2014) have been successfully used as liquid lipid in wax‐based NLC formulations (Table 2).…”

Section: Wax‐based Delivery Systemsmentioning

confidence: 99%

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Wax‐based delivery systems: Preparation, characterization, and food applications

Soleimanian

Goli

Shirvani

et al. 2020

Comp Rev Food Sci Food Safe

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The development of lipid-based delivery systems has attracted much attention over the last years and a wide variety of strategies and formulations are currently available to encapsulate, protect, and target delivery of bioactive and functional lipophilic constituents within the food and pharmaceutical industries. Waxes are crystalline lipid material, consisting of a complex mixture of long-chain fatty acids and fatty alcohols, hydrocarbons, aldehydes, and ketones and show great promises as constituents of carrier systems. Most of waxes are classified under food-grade category and show high availability at a low cost. This review article has provided a comprehensive summary of research on major carriers containing wax as one of the main constituents, including solid lipid nanoparticles, nanostructured lipid carriers, oleogels, and Pickering emulsions, with a focus on their food applications. The physical and chemical nature of natural waxes are described in the first while the second part deals with the structure, formulation, main methods of preparation, characterization, and finally utilization of each type of wax-based delivery system for specific food applications.

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“…Crude edible vegetable oils are readily available, economic and green chemistry products with functional food properties that exhibit numerous health benefits for patients and have been used in LBDDS [ 14 ]. Grapeseed, flaxseed and soybean oil are rich in poly unsaturated fatty acid, such as α-linoleic acid, content which is positively associated with cardiovascular health due to down-regulation of low-density lipoprotein cholesterol production.…”

Section: Introductionmentioning

confidence: 99%

Design, Optimization, Manufacture and Characterization of Efavirenz-Loaded Flaxseed Oil Nanoemulsions

2020

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The formation, manufacture and characterization of low energy water-in-oil (w/o) nanoemulsions prepared using cold pressed flaxseed oil containing efavirenz was investigated. Pseudo-ternary phase diagrams were constructed to identify the nanoemulsion region(s). Other potential lipid-based drug delivery phases containing flaxseed oil with 1:1 m/m surfactant mixture of Tween® 80, Span® 20 and different amounts of ethanol were tested to characterize the impact of surfactant mixture on emulsion formation. Flaxseed oil was used as the oil phase as efavirenz exhibited high solubility in the vehicle when compared to other vegetable oils tested. Optimization of surfactant mixtures was undertaken using design of experiments, specifically a D-optimal design with the flaxseed oil content set at 10% m/m. Two solutions from the desired optimization function were produced based on desirability and five nanoemulsion formulations were produced and characterized in terms of in vitro release of efavirenz, physical and chemical stability. Metastable nanoemulsions containing 10% m/m flaxseed oil were successfully manufactured and significant isotropic gel (semisolid) and o/w emulsions were observed during phase behavior studies. Droplet sizes ranged between 156 and 225 nm, zeta potential between −24 and −41 mV and all formulations were found to be monodisperse with polydispersity indices ≤ 0.487.

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Effect of vegetable oils on obtaining lipid nanocarriers for sea buckthorn extract encapsulation

Cited by 22 publications

References 29 publications

Abundance of active ingredients in sea-buckthorn oil

Abundance of active ingredients in sea-buckthorn oil

Wax‐based delivery systems: Preparation, characterization, and food applications

Design, Optimization, Manufacture and Characterization of Efavirenz-Loaded Flaxseed Oil Nanoemulsions

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