Effect of various chlorhexidine regimens on salivary bacteria and de novo plaque formation

Sekino, Satoshi; Ramberg, Per; Uzel, Naciye Guzin; Socransky, S. S.; Lindhe, Jan

doi:10.1034/j.1600-051x.2003.00420.x

Cited by 49 publications

(42 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[6] In the present study, the use of Chlorhexidine showed a significant reduction in both gingival and plaque scores. Similar results were reported by Loe H et al (1970) [9] and Sekino S et al (2003) [10] where the use of Chlorhexidine mouth rinse as an adjunct reduced the number of microorganisms. The results were also in agreement with Dehlen (1984) [11] who reported that mouth rinsing with Chlorhexidine significantly (p < 0.001) reduced the number of bacteria.…”

Section: Discussionsupporting

confidence: 78%

Short Term Effects of Magnetised Water and Chlorhexidine on Plaque Accumulation and Gingival Inflammation- A Randomised Clinical Study

2016

AIMDR

View full text Add to dashboard Cite

Background: The beneficial uses of magnetized water in medical sciences has been tried but its application in the field of dentistry is still at its infancy. Magnetized water can be a cheaper alternative to adjuncts used for chemical plaque control. The aim of the study was to evaluate the efficacy of conventionally prepared magnetized water and 0.2% Chlorhexidine on gingival and plaque status among children attending a Government Dental College. Methods: The present double blinded randomized control clinical study was carried out in Department of Pedodontics, Govt. Dental College, Srinagar. A total of 75 children between 12-15 years were randomly allocated into 3 groups A, B and C, each comprising of 25 subjects who were asked to rinse with Mint Water (Control Group), Magnetized water and 0.2% Chlorhexidine respectively. Examination was carried on day 0 (Baseline), 14 days (2 weeks) and 21 days (3 weeks) whose Turesky-Gilmore Modification of Quigley Hein Plaque Index and Gingival Index were assessed. Results: There was a significant difference in the mean PI and GI scores of magnetized water and Chlorhexidine groups when compared with that of Control group, both at 14 days (2 weeks) and at 21 days (3 weeks). Conclusion: It was concluded that both Magnetized water and 0.2% Chlorhexidine showed less plaque accumulations as well as improvement in the gingival status as compared to the control group.

show abstract

Section: Discussionsupporting

confidence: 78%

Short Term Effects of Magnetised Water and Chlorhexidine on Plaque Accumulation and Gingival Inflammation- A Randomised Clinical Study

2016

AIMDR

View full text Add to dashboard Cite

show abstract

“…Studies with similar aims have been published with sample sizes similar to that of this study. 16,21 In our study, no significant differences were observed in terms of gingival bleeding after 14 days. However, gingivitis was observed in 14.93% and 13.95% of sites in users of the 0.12% and 0.20% chlorhexidine solutions, demonstrating an establishment of inflammation.…”

Section: Discussionmentioning

confidence: 49%

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

Neto¹,

Parolo²,

Rösing

et al. 2008

Braz. oral res.

View full text Add to dashboard Cite

The aim of the present study was to evaluate the effect of two chlorhexidine rinsing solutions (0.12% and 0.2%) on plaque and gingival bleeding. Ten dental students participated in this double-blind, cross-over study, rinsing twice a day, for one minute, with each one of the tested solutions for fourteen days. A wash-out period of one week between treatments was observed. In order to assess gingival bleeding, the van der Weijden et al. 1 (1994) index was used. The plaque indexes used were those of Quigley, Hein 2 (1962) and Silness, Löe 3 (1964). In the pre-experimental period, subjects received oral hygiene instructions and dental prophylaxis. The results revealed no significant differences between both concentrations in relation to plaque and gingival bleeding. Mean values (± standard deviation) of the Quigley & Hein index were 0.25 ± 0.16 for the 0.12% solution and 0.23 ± 0.26 for the 0.2% solution (p = 0.4838). Mean values (± standard deviation) of the Silness-Löe index were 0.12 ± 0.10 for the 0.12% solution and 0.11 ± 0.11 for the 0.2% solution (p = 0.7592). The bleeding index mean values at the end of the study were not different for both concentrations with mean values (± standard deviation) of 14.93% ± 6.68% and 13.95 ± 9.24% for the 0.12% and 0.2% solutions, respectively. Although an increase in gingival bleeding was observed, both concentrations were able to control dental plaque.

show abstract

“…34 More recently we have found a similar concentration of yeast (mean, 387/ml) in the saliva of 134 children 7-8 years old (Boyd and Cannon, unpublished data); this compares with a bacterial concentration of approximately 10 7 -10 8 /ml saliva. 36,37 Despite the low concentrations of yeast in the oral cavity, they can still give rise to oral disease, usually when the host's immune system becomes compromised or suppressed. 2,3 These oral fungi are, therefore, opportunistic pathogens.…”

Section: Introductionmentioning

confidence: 99%

Antifungal drug resistance of oral fungi

2010

View full text Add to dashboard Cite

Fungi comprise a minor component of the oral microbiota but give rise to oral disease in a significant proportion of the population. The most common form of oral fungal disease is oral candidiasis, which has a number of presentations. The mainstay for the treatment of oral candidiasis is the use of polyenes, such as nystatin and amphotericin B, and azoles including miconazole, fluconazole, and itraconazole. Resistance of fungi to polyenes is rare, but some Candida species, such as Candida glabrata and C. krusei, are innately less susceptible to azoles, and C. albicans can acquire azole resistance. The main mechanism of high-level fungal azole resistance, measured in vitro, is energy-dependent drug efflux. Most fungi in the oral cavity, however, are present in multispecies biofilms that typically demonstrate an antifungal resistance phenotype. This resistance is the result of multiple factors including the expression of efflux pumps in the fungal cell membrane, biofilm matrix permeability, and a stress response in the fungal cell. Removal of dental biofilms, or treatments to prevent biofilm development in combination with antifungal drugs, may enable better treatment and prevention of oral fungal disease.

show abstract

Effect of various chlorhexidine regimens on salivary bacteria and de novo plaque formation

Abstract: The daily use of chlorhexidine as an adjunct to mechanical tooth cleaning markedly reduced the number of microorganisms that could be detected in saliva. The number of salivary bacteria may have influenced the amount of plaque that formed during an early phase of no oral hygiene.

Cited by 49 publications

References 31 publications

Short Term Effects of Magnetised Water and Chlorhexidine on Plaque Accumulation and Gingival Inflammation- A Randomised Clinical Study

Short Term Effects of Magnetised Water and Chlorhexidine on Plaque Accumulation and Gingival Inflammation- A Randomised Clinical Study

Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding

Antifungal drug resistance of oral fungi

Contact Info

Product

Resources

About