Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes)

Inui, Madoka; Adachi, Tomohiko; Takenaka, Shigeo; Inui, Hiroshi; Nakazawa, Masami; Ueda, Mitsuhiro; Watanabe, Hidenobu; Mori, Chisato; Iguchi, Taisen; Miyatake, Kazutaka

doi:10.1016/s0300-483x(03)00340-8

Cited by 175 publications

(72 citation statements)

References 20 publications

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“…Recent reports have demonstrated that their presence in aquatic environment may pose potential hazard to the aquatic organisms [14,15]. Thus, it is necessary to assess the ecological risk of these compounds with the measured environmental concentrations (MECs) on organisms.…”

Section: Environmental Risk Assessmentmentioning

confidence: 99%

“…Owing to the lack of information on the removal of parabens during advanced treatments, it is required to assess whether the additional process, such as advanced oxidation and membrane separation, can further reduce the levels of parabens in the effluents of WWTPs. Considering the fact that several parabens are slightly toxic to aquatic invertebrates and fish [14,15], the assessment for the potential environmental risk of these parabens to the aquatic ecosystems is warranted.…”

Section: Introductionmentioning

confidence: 99%

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Occurrence, fate and risk assessment of parabens and their chlorinated derivatives in an advanced wastewater treatment plant

Shi

Gao

et al. 2015

Journal of Hazardous Materials

144

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Section: Environmental Risk Assessmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Occurrence, fate and risk assessment of parabens and their chlorinated derivatives in an advanced wastewater treatment plant

Shi

Gao

et al. 2015

Journal of Hazardous Materials

144

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“…Harvey and Darbre (2004) and Harvey and Everett (2006) have noted that all types of bodycare cosmetics applied to the skin (not just underarm cosmetics) can be a source of local oestrogenic chemical input to the breast and should be considered in risk assessments. Furthermore, there are also an increasing number of other ingredients in various cosmetics that have been shown to be endocrine active or oestrogenic [for example polycyclic musks (Gomez et al, 2005;Schreurs et al, 2005), UV ¼lters (Schlumpf et al, 2001;Inui et al, 2003;Koda et al, 2005), aluminium chlorhydrate (Darbre, 2006b), triclosan (Gee et al, 2008), phthalates (Jobling et al, 1995;Harris et al, 1997;Okubo et al, 2003), cyclosiloxanes (McKim et al, 2001;He et al, 2003)] and risk assessments should take into account mixture and combined repeated exposure effects.…”

Section: Regulatory Status Of Parabensmentioning

confidence: 99%

“…Thus common coingredients in cosmetic formulations may interact in mixtures, resulting in higher skin and body burdens of parabens [and other endocrine active compounds common in cosmetics, e.g. phthalates (Jobling et al, 1995;Harris et al, 1997;Okubo et al, 2003), polycyclic musks (Gomez et al, 2005;Schreurs et al, 2005), UV ¼lters (Schlumpf et al, 2001;Inui et al, 2003;Janjua et al, 2004;Koda et al, 2005), aluminium chlorhydrate (Darbre, 2006b), triclosan (Gee et al, 2008) and cyclosiloxanes (McKim et al, 2001;He et al, 2003)]. …”

Section: Introductionmentioning

confidence: 99%

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Darbre

Harvey

2008

J of Applied Toxicology

595

375

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This toxicology update reviews research over the past four years since publication in 2004 of the ¼rst measurement of intact esters of p-hydroxybenzoic acid (parabens) in human breast cancer tissues, and the suggestion that their presence in the human body might originate from topical application of bodycare cosmetics. The presence of intact paraben esters in human body tissues has now been con¼rmed by independent measurements in human urine, and the ability of parabens to penetrate human skin intact without breakdown by esterases and to be absorbed systemically has been demonstrated through studies not only in vitro but also in vivo using healthy human subjects. Using a wide variety of assay systems in vitro and in vivo, the oestrogen agonist properties of parabens together with their common metabolite ( p-hydroxybenzoic acid) have been extensively documented, and, in addition, the parabens have now also been shown to possess androgen antagonist activity, to act as inhibitors of sulfotransferase enzymes and to possess genotoxic activity. With the continued use of parabens in the majority of bodycare cosmetics, there is a need to carry out detailed evaluation of the potential for parabens, together with other oestrogenic and genotoxic co-formulants of bodycare cosmetics, to increase female breast cancer incidence, to interfere with male reproductive functions and to in½uence development of malignant melanoma which has also recently been shown to be in½uenced by oestrogenic stimulation.

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“…The BP-4 levels that are commonly found in surface waters (in the low µg L −1 range; Fent et al, 2010) are generally too low to cause acute toxicity (Fent et al, 2010a), but chronic effects cannot be excluded. Indeed, in vitro tests have shown that BP-4 has anti-estrogenic and anti-androgenic activity , but also estrogenic activity in fish (Inui et al, 2003;. As far as human exposure is concerned, the only available data are related to allergic reactions upon dermal contact with products containing BP-4 (Alanko et al, 2001;Caruana et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Photochemical processes involving the UV absorber benzophenone-4 (2-hydroxy-4-methoxybenzophenone-5-sulphonic acid) in aqueous solution: Reaction pathways and implications for surface waters

et al. 2013

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processes involving the UV absorber benzophenone-4 (2-hydroxy-4-methoxybenzophenone-5-sulphonic acid) in aqueous solution. Reaction pathways and implications for surface waters. Wat. Res. 2013, 47, 5943-5953. DOI: 10.1016/j.waters.2013 You may download, copy and otherwise use the AAM for non-commercial purposes provided that your license is limited by the following restrictions:(1) You may use this AAM for non-commercial purposes only under the terms of the CC-BY-NC-ND license.(2) The integrity of the work and identification of the author, copyright owner, and publisher must be preserved in any copy. AbstractThe sunlight filter benzophenone-4 (BP-4) is present in surface waters as two prevailing forms, the singly deprotonated (HA − ) and the doubly deprotonated one (A 2− ), with pK a2 = 7.30±0.14 (µ±σ, by dissociation of the phenolic group). In freshwater environments, BP-4 would mainly undergo degradation by reaction with • OH and direct photolysis. The form HA − has a second-order reaction rate constant with • OH ( OH k • ) of (1.87±0.31)⋅10 10 M −1 s −1 and direct photolysis quantum yield Φ equal to (3.2±0.6)⋅10 −5 . The form A 2− has (8.46±0.24)⋅10 9 M −1 s −1 as the reaction rate constant with • OH and (7.0±1.3)⋅10 −5 as the photolysis quantum yield. The direct photolysis of HA − likely proceeds via homolytic breaking of the O-H bond of the phenolic group to give the corresponding phenoxy radical, as suggested by laser flash photolysis experiments. Photochemical modelling shows that because of more efficient direct photolysis (due to both higher sunlight absorption and higher photolysis quantum yield), the A 2− form can be degraded up to 3 times faster than HA − in surface waters. An exception is represented by low-DOC (dissolved organic carbon) conditions, where the • OH reaction dominates degradation and the transformation kinetics of HA − is faster compared to A 2− . The half-life time of BP-4 in mid-latitude summertime would be in the range of days to weeks, depending on the environmental conditions. BP-4 also reacts with Br 2 −• , and a rate constant

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Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes)

Cited by 175 publications

References 20 publications

Occurrence, fate and risk assessment of parabens and their chlorinated derivatives in an advanced wastewater treatment plant

Occurrence, fate and risk assessment of parabens and their chlorinated derivatives in an advanced wastewater treatment plant

Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks

Photochemical processes involving the UV absorber benzophenone-4 (2-hydroxy-4-methoxybenzophenone-5-sulphonic acid) in aqueous solution: Reaction pathways and implications for surface waters

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