The aim of the study was to define the influence of cultivation methods involving the application of growth biostimulators and herbicide on the total yield of edible potato. The field research was conducted in 2015-2017 in the area of eastern Poland, in Lublin Voivodeship. The experiments were performed in three replicates using the randomised split-block method. The examined factors included: factor I -three early cultivars of edible potato (Owacja, Bellarosa, Vineta), factor II -cultivation methods involving the application of growth biostimulators and herbicide: GreenOK-Universal Pro and Asahi SL as well as their combination with the Avatar 293 ZC herbicide. The highest total yield of tubers was obtained from treatment 4, where prior to sprouting mechanical tillage was used, and after the final shaping of ridges and just before sprouting the Avatar 293 ZC herbicide was applied at a dose of 1.5 dm 3 ha -1 , and then after sprouting the GreenOK Universal-PRO was applied three times at doses: 0.10 dm 3 ha -1 -full moon-end of seeding + 0.15 dm 3 ha -1 -covering inter-rows + 0.15 dm 3 ha -1 -formation of flower buds (an average of 41.8 t ha -1 ), and from treatment 5, in which mechanical tillage was used prior to seeding, and after the ultimate formation of furrows before seeding of potato plants, Avatar herbicide 293 was applied in a dose of 1.5 dm 3 ha -1 (total yield amounted to, on average, 40.6 t ha -1 ). Potato cultivars cultivated in the experiment and meteorological conditions during the conducted tests also had a significant impact on the size of the total yield. Cultivar Owacja produced the highest yields (an average of 41.4 t ha -1 ). The largest total yield was collected in 2016 (an average of 42.8 t ha -1 ). A significant influence of the experimental factors on the structure of large tuber yields was also found. K e y w o r d s: potato, total yield, biostimulators, herbicide