Effect of trichlorfon on some haematological and biochemical changes in Cyprinus carpio: The ameliorative effect of lycopene

Yonar, Serpil Mişe; Yonar, M. Enis; Pala, Ayşegül; Sağlam, Naim; Sakin, Fatih

doi:10.1016/j.aqrep.2019.100246

Cited by 19 publications

(6 citation statements)

References 35 publications

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“…In the existing experiment, the RBC number and the Ht and Hb values were signi cantly declined by the inclusion of OTC in the diet of O. mykiss fed with low dose of AA (100 mg/kg diet). These results suggested that OTC has caused anemia condition in O. mykiss, which may be a result of erythropoiesis inhibition and also increased erythrocyte lysis (Ramesh et al 2018;Yonar et al 2020). Similarly, signi cant reductions in RBC, Ht, and Hb values were observed by Omoregie and Oyebanji (2002) in Oreochromis niloticus fed diets incorporated with OTC.…”

Section: Discussionmentioning

confidence: 73%

The ameliorative role of ascorbic acid against blood disorder, immunosuppression and oxidative damage of oxytetracycline in rainbow trout (Oncorhynchus mykiss)

Moradi¹,

Javanmardi²,

Gholamzadeh³

et al. 2021

Preprint

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This experiment aimed to determine the possible beneficial effects of dietary ascorbic acid (AA) on hematological indices, immune responses, and antioxidative capacity of Oncorhynchus mykiss treated with antibiotic oxytetracycline (OTC). 150 fish were divided evenly among five experimental groups (30 fish of each, in 3 replicates) receiving diets containing OTC (0 and 100 mg per kg fish weight) and AA (100, 200, 400 and 800 mg per kg fish diet) for 28 days. Treatments include group A or control (100 mg AA without OTC), group B (100 mg AA with OTC), group C (200 mg AA with OTC), group D (400 mg AA with OTC), and group E (800 mg AA with OTC). The results obtained showed that the hematological indices (red blood cells, white blood cells, hematocrit, hemoglobin and neutrophils), immunological parameters (plasma lysozyme, plasma complement and skin mucus alkaline phosphatase activities), and antioxidant enzymes activities (superoxide dismutase and catalase) were significantly decreased by OTC in O. mykiss fed control diet (P < 0.05). The results also revealed that OTC significantly increased the activity of biochemical enzymes (aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase) in the plasma of O. mykiss fed control diet (P < 0.05). However, in comparison to the control diet, feeding fish with higher amounts of AA (400 and 800 mg/kg diet) significantly restored the hematological, immunological, and antioxidative responses in OTC treated groups (p < 0.05). These findings show that the dietary supplementation of AA at 400 or 800 mg/kg diet is beneficial in relieving O. mykiss from OTC-induced oxidative stress and immunosuppression.

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Section: Discussionmentioning

confidence: 73%

The ameliorative role of ascorbic acid against blood disorder, immunosuppression and oxidative damage of oxytetracycline in rainbow trout (Oncorhynchus mykiss)

Moradi¹,

Javanmardi²,

Gholamzadeh³

et al. 2021

Preprint

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“…In C. macropomum , exposed to culture tank water with 70% alcohol was also reported decrease in MCHC ( Barriga et al, 2020 ). This reduction in the total number of leukocytes and neutrophils may indicate a decrease in immunity, as these defense cells, in general, respond to parasitic infection and stress in fish ( Urbinati et al, 2020 ; Yonar et al, 2020 ). In addition, this reduction in the number of leukocytes due to the decrease in the number of neutrophils may also be related to damages to the branchial lamellar epithelium due to exposure to 70% alcohol.…”

Section: Discussionmentioning

confidence: 99%

Essential oil of Piper hispidum (Piperaceae) has efficacy against monogeneans, and effects on hematology and gill histology of Colossoma macropomum

Alves,

Baia,

Farias

et al. 2024

Rev. Bras. Parasitol. Vet.

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This study investigated for the first time the effectiveness of therapeutic baths with essential oil (EO) of Piper hispidum against monogeneans Anacanthorus spathulatus, Notozothecium janauachensis, Mymarothecium boegeri and Linguadactyloides brinkmanni from the gills of Colossoma macropomum, as well as the hematological and histological effects on this fish. In therapeutic baths, 100 mg/L of P. hispidum essential oil and two control groups (water from the culture tank and water from the culture tank with 70% alcohol) were exposed for 1 h/day, with intervals of 48 hours for 3 days, and three replicates each were used. Therapeutic baths with 100 mg/L of P. hispidum essential oil had an efficacy of 78.6% against monogeneans. The toxicity of this essential oil was low, since there were a few physiological and histopathological changes that did not compromise the functioning of the gills of the fish. Therefore, 100 mg/L of P. hispidum essential oil was effective for controlling monogeneans in C. macropomum, when short therapeutic baths were used without compromising the health of the exposed fish.

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“…Several studies have suggested the use of lycopene as a strong antioxidant to attenuate the oxidative stress reactions in fish species subjected to insecticides ( Dawood et al, 2020 ). Lycopene displayed an ameliorative effect against trichlorfon oxidative stress in common carp ( Cyprinus carpi ) ( Yonar et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

Lycopene supplementation: effects on oxidative stress, sex hormones, gonads and thyroid tissue in tilapia Oreochromis niloticus during Harness® exposure

Ismail,

Hamed,

Sayed

2023

Front. Physiol.

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Harness® is a commercial herbicide that contains acetochlor at a concentration of 84% as an active ingredient. Ubiquitous, persistent, and substantial uses of Harness® in agricultural processes have resulted in the pollution of nearby water sources, posing a threat to various aquatic biotas, including fish. The effects of Harness® toxicity on fish health are little known. So, this study aimed to describe the impact of herbicide Harness® on the oxidative stress and reproductive and thyroid performance of male and female tilapia (Oreochromis niloticus) and also investigate the prospective role of the natural antioxidant lycopene supplementation in dismissing the adverse properties of Harness®. Antioxidant enzyme (catalase, superoxide dismutase, and total antioxidant capacity) and hormone measurements (T, E2, T3, and T4) were carried out, and gonadal and thyroid follicle histological sections were examined as a method to investigate the effects of Harness® toxicity on fish. Male and female tilapia were exposed to 10 μmol/L and 100 μmol/L of Harness® and treated with 10 mg lycopene/kg for 15 days of exposure. Our results demonstrated that the antioxidant enzyme activity was altered by Harness exposure and serum T for both males and females dropped; also, female E2 levels decreased, but male E2 increased. Exposure to higher dose of Harness® induced elevation in both T3 and T4 levels, although the low exposure dose stimulated T4 levels. Harness® exposure prompted histological variations and degenerative changes in testicular, ovarian, and thyroid follicle tissues. Lycopene supplement administration diminished oxidative stress induced by Harness®, alleviating its endocrine disparaging effects by neutralizing T3, T4, T, and E2 and ameliorating the histological structure of gonadal and thyroid tissues. In conclusion, lycopene supplementation was preformed to normalize the alterations and oxidative damage caused by Harness® in Nile tilapia, suggesting that lycopene-supplemented diet functioned as potent antioxidants and had the ability to alleviate oxidative stress and thyroid and reproductive toxicity caused by herbicide Harness®. Moreover, it is crucial to take appropriate care when consuming herbicides to defend the aquatic environment.

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Effect of trichlorfon on some haematological and biochemical changes in Cyprinus carpio: The ameliorative effect of lycopene

Cited by 19 publications

References 35 publications

The ameliorative role of ascorbic acid against blood disorder, immunosuppression and oxidative damage of oxytetracycline in rainbow trout (Oncorhynchus mykiss)

The ameliorative role of ascorbic acid against blood disorder, immunosuppression and oxidative damage of oxytetracycline in rainbow trout (Oncorhynchus mykiss)

Essential oil of Piper hispidum (Piperaceae) has efficacy against monogeneans, and effects on hematology and gill histology of Colossoma macropomum

Lycopene supplementation: effects on oxidative stress, sex hormones, gonads and thyroid tissue in tilapia Oreochromis niloticus during Harness® exposure

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