Effect of Topical Sucralfate vs Clindamycin on Posttonsillectomy Pain in Children Aged 6 to 12 Years

Abstract

Iranian Registry of Clinical Trials registration number: IRCT201303209014N16.

Does topical use of autologous serum help to reduce post-tonsillectomy morbidity? A prospective, controlled preliminary study

“…As pain is a subjective symptom, the amount of analgesic used after tonsillectomy and the duration of analgesic use are accepted as objective criteria to evaluate pain. Pain after tonsillectomy lasts about 9 days, and the pain is at its most intense on post-operative day 1, and it decreases thereafter 12 . In our study, the average duration of analgesic use by patients was 3.53 ± 1.88 days.…”

“…As the post-operative area is no longer covered by mucosa, there is an infection risk. Some studies have reported that antibiotics administered after tonsillectomy decrease pain by reducing local flora and inflammation 4 , 12 . Other studies have shown that antibiotic treatments have no effect on post-operative pain 5 , 6 .…”

“…A variety of methods have been employed with the aim of reducing post-operative pain and haemorrhage. These include: obliteration of the tonsillar fossa; 3 the use of various antibiotics; 4 – 6 the injection of local anaesthetic 7 – 9 or steroids 10 , 11 to the tonsillar fossa; the use of mouthwash containing antibiotics; 12 the application of sucralfate to the tonsil region; 12 – 14 the use of honey; 15 the application of fibrin glue; 1 , 2 , 9 aromatherapy; 16 transcutaneous electrostimulation; 17 and acupuncture treatments 18 …”

The Efficacy of Perioperative Antibiotic Therapy in Tonsillectomy Patients

“…However, Karaman et al analyzed the effects of local antibiotic prophylaxis in tonsillectomy patients and found a reduction in both aerobic and non-aerobic bacterial counts in tonsillar niches compared with patients who had not received topical antibiotic therapy [20]. Local perioperative antibiotic prophylaxis remains an open issue, as some recent studies have confirmed reduced pain and postoperative bleeding in patients following local perioperative administration of clindamycin [37]. However, there is also research questioning this concept [38].…”

Effectiveness of hyaluronic acid in post-tonsillectomy pain relief and wound healing: A prospective, double-blind, controlled clinical study

“…However, the commonly prescribed acetaminophen may not be adequate for post-tonsillectomy pain relief without codeine and at higher doses it may cause hepatic toxicity (5). Therefore, there is an ongoing research on the investigation of effectiveness of many surgical and pharmacological products in post-tonsillectomy pain management (2,4,5,7,9,23,26). Subramayam et al (2) reported their own experience on the use of ATC acetaminophen, dexamethasone and ibuprofen in pain management as no increase in the incidence of inadequate pain control or serious complications.…”