Effect of the herbicide glyphosate on liver lipoperoxidation in pregnant rats and their fetuses

Time- and Dose-Dependent Effects of Roundup on Human Embryonic and Placental Cells

“…This was of particular interest since Roundup and/or glyphosate were suggested to disturb human (Savitz et al 1997) and rat pregnancies (Daruich et al 2001, Beuret et al 2005, mouse kidney (Peluso et al 1998), rabbit spermatogenesis (Yousef et al 1995), and other human tissues (Monroy et al 2005).…”

Saccharomyces Cerevisiae as a Tool to Evaluate the Effects of Herbicides on Eukaryotic Life

“…Possible oxidative damage induced by G-containing herbicides has been already postulated (Beuret et al, 2005;Gehin et al, 2005;Pieniazek et al, 2004;Richard et al, 2005). Considering these findings in the light of our previous investigations on nucleotide patterns, which suggested a redox imbalance in herbicide treated cells, we decided to investigate if herbicide treatments could affect the enzymatic activity of catalase and superoxide dismutase (SOD), two key enzymes in the cell response to oxidative stress.…”

Glyphosate, pathways to modern diseases IV: cancer and related pathologies

“…ROS causes irreversible DNA impairment, damage to lipid membranes and promotes the toxic carbonyl, malondialdehyde [62,63]. Excessive lipid peroxidation induced with ingestion of glyphosate residues likely leads to an overload of maternal and foetal antioxidant defence systems following liver damage, as shown in rat studies by Beuret et al [64].…”