Effect of tetracalcium phosphate/monetite toothpaste on dentin remineralization and tubule occlusion in vitro

Medvecký, Ľubomír; Štulajterová, Radoslava; Giretová, Maria; Mincik, Jozef; Vojtko, Marek; Balko, Ján; Briančin, Jaroslav

doi:10.1016/j.dental.2017.11.022

Cited by 25 publications

(25 citation statements)

References 43 publications

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“…It was found that the negative control group showed weak remineralization after pH cycling in this study. The same phenomenon was observed in other studies 15,40) . Researchers have presented a possible explanation with self-assembly theory, indicating that type I collagen has complex and orderly structures that play an active role in guiding minerals infiltration and nucleation 11) .…”

Section: Discussionsupporting

confidence: 90%

Effect of poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite for dentin remineralization <i>in vitro </i>

Zhang

Mai

et al. 2021

Dent. Mater. J.

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The poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite was fabricated as a novel biomineralization material function in preventing caries. Demineralized bovine dentin specimens were prepared and randomly divided into 5 groups (i. α-TCP, ⅱ. γ-PGA, ⅲ. γ-PGA/TCP, ⅳ. CPP-ACP, and ⅴ. deionized water) and subjected to 14 days of pH cycling. Remineralization ability was evaluated by lesion depth, mineral loss and microhardness. The morphology of dentin depositions was observed with scanning electron microscope (SEM), the crystal structure was determined by X-ray diffraction (XRD), and the wettability was tested by contact angle measurements. ANOVA revealed specimens treated by γ-PGA/TCP presented the statistically least lesion depth (p<0.01) and mineral loss (p<0.001), and the highest hardness (p<0.001). SEM revealed prominent intra-and inter-tubular precipitates in both γ-PGA and γ-PGA/TCP groups. The XRD patterns of the deposition structures in all groups were similar to those of sound dentin, and the contact angle of water decreased after γ-PGA/TCP treatment.

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Section: Discussionsupporting

confidence: 90%

Effect of poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite for dentin remineralization <i>in vitro </i>

Zhang

Mai

et al. 2021

Dent. Mater. J.

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“…Brushite DCPD remains one of the most studied calcium phosphate materials because it has several other technological applications as additives in food or dietary supplement [11] and in the pharmaceutical industry as tablet excipient and toothpaste [12,13]. For these purposes, the thermal degradation of DCPD has been extensively studied for several years using different experimental techniques but controversial results still remain, especially on the intermediate phases that may be formed during the dehydration process to give crystalline Calcium Pyrophosphate (Ca 2 P 2 O 7 , CPP) [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Complex phase evolution of Brushite-based calcium phosphate CaHPO4·2H2O using in situ high temperature X-ray diffraction and thermal analysis

Hazzat¹,

Hamidi²,

Halim³

et al. 2020

Preprint

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This study focused on a detailed examination of the thermal behavior of Brushite-based calcium phosphate (CaHPO 4 .2H 2 O, DCPD) to identify and characterize the intermediate phases which have been the subject of previous several controversies. For that, in situ high-temperature X-ray diffraction supported by infrared spectroscopy, thermal analysis, and scanning electron microscopy analysis were used and the results showed that the progressive thermal stress of DCPD in air resulted in a heterogeneous formulation consisting of dibasic calcium phosphate anhydrous (CaHPO 4 , DCPA) and an amorphous phase, which appears at low temperatures (~160 °C) and persists up to 375 °C. The deep examination of the amorphous phase by infrared spectroscopy revealed that its chemical composition is similar to that of disordered calcium pyrophosphate (Ca 2 P 2 O 7 , CPP) with the appearance of a characteristic band δ(P-O-P), located at 740 cm -1 . This IR band is shifted to low frequencies (725 cm -1 ) as the temperature is increased, indicating the crystallization of the amorphous phase into γ-CPP. The high temperature treatment (≥ 375 °C) leads to b-CPP polymorph. According to the present characterization results, obtaining pure DCPA from the thermal dehydration of DCPD is not effective and leads to biphasic materials including an amorphous phase.

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“…3 Our aim in this experimental study is to investigate the effect of TTCP, which is used as a ller in dentistry and is known to have remodeling potential. 4,5 Materials And Methods…”

Section: Introductionmentioning

confidence: 99%

Tetracalcium Phosphate Treatment on Experimental Fracture Model in Rats

Kaymaz

Yılmaz²,

Taşova

et al. 2020

Preprint

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Background: Studies have shown that bioactive cements have beneficial bone-forming effects. Our objective in the present study is to investigate the efficacy of tetracalcium phosphate (TTCP) on fracture healing in rat femur.Materials and methods: Forty-two female Wistar Albino rats randomized into two groups (groups 1 and 2, n=21 for each). The left femur of all animals was fractured by osteotomy after deep anesthesia with ketamine. Additional procedure was not applied to the rats in group 1. Rats in Group 2, following osteotomy were applied to the fracture line approximately 2 cc TTCP. The animals were sacrificed on the 1st, 2nd and 3rd post-operative weeks (each week 7 animals were sacrificed from each group) and the broken femur were removed. The femur were examined first radiographically and second, histopathologically.Results: Radiologically, callus maturity and bone union increased with time in both groups. But no significant differences were found regarding callus maturity and bone union in weekly comparisons (Anteroposterior plain: p:0.53, p:0.37, p:0.42, Lateral plain p:0.26, p:0.42, p:0.87). Histopathologically, the fractures healed normally as the weeks progressed in both groups. In the comparison of both groups, no significant difference was found outside the 1st week, although the histological scores of group 2, who were treated for all weeks, were higher in terms of fracture healing (p:0,024, p:104,p:462).Conclusions: Although no significant difference was found in the comparison of both groups except for the first week, the histological scores of the group 2 who received TTCP in all weeks were higher in terms of fracture healing. According to the results of this study, we think that TTCP can be useful especially in the early stages of fracture healing.

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Effect of tetracalcium phosphate/monetite toothpaste on dentin remineralization and tubule occlusion in vitro

Cited by 25 publications

References 43 publications

Effect of poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite for dentin remineralization <i>in vitro </i>

Effect of poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite for dentin remineralization <i>in vitro </i>

Complex phase evolution of Brushite-based calcium phosphate CaHPO4·2H2O using in situ high temperature X-ray diffraction and thermal analysis

Tetracalcium Phosphate Treatment on Experimental Fracture Model in Rats

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