Effect of surgical repair of secundum-type atrial septal defect on right atrial, right ventricular, and left ventricular volumes in adults

Hemodynamic improvement is faster after percutaneous ASD closure than after surgery

“…Similar increase in end-diastolic diameter [33] and volume of LV after both surgical and percutaneous ASD closure has been demonstrated earlier in adult population [7,8,27].…”

“…Transcatheter closure of the ASD has evolved over the last 20 years [4][5][6]. Myocardial performance index has been shown to improve and LV dimensions to increase after ASD closure [7,8]. These changes are related to normalization of the right ventricular (RV) dimensions and the motion of the interventricular septum [9].…”

Comparison of cardiac function in children after surgical and Amplatzer occluder closure of secundum atrial septal defects

“…The recovery of the right ventricular size is described in more than 80% of children and in 77% of adults who were operated upon [6,9,12,17,[22][23][24][25]. Similar changes were observed in our series of patients.…”

“…The recovery of right ventricle (RV) and right atrium (RA) sizes after surgical and percutaneous ASD closure have also been described [6,12,14,17]. These parameters return to normal values in 90% of surgical patients.…”

Improvement after Surgical Closure of Secundum Atrial Septal Defects in Adults

“…Literatures concerned about sildenafil found that, mid-term oral sildenafil therapy led to significant improvement in pulmonary hemodynamics, functional class and/or exercise tolerance [32,33]. Its use still need work up to prove its efficacy in pulmonary hypertension secondary to congenital heart defects.…”