Effect of surface finish on the osseointegration of laser-treated titanium alloy implants

Götz, Hermann; Müller, M. E.; Emmel, A.; Holzwarth, U.; Erben, Reinhold G.; Stangl, R.

doi:10.1016/j.biomaterials.2003.11.002

Cited by 214 publications

(123 citation statements)

References 28 publications

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“…Since this work many studies have proposed a need for pores exceeding 650 µm for bone formation, to ensure rapid vascularisation and for the survival of transplanted cells within tissue engineered scaffolds constructs. By facilitating capillary formation, pores greater than 650 µm can lead to direct osteogenesis while pores smaller than 300 µm have the potential to promote osteochondral ossification (Tsuruga et al, 1997;Cornell, 1999;Kuboki et al, 2001;Götz et al, 2004;Karageorgiou et al, 2005;Lien et al, 2009;Roosa et al, 2010). However, it is important to identify the upper limits in pore size as large pores may compromise the mechanical properties of the scaffolds by increasing void volume (Karageorgiou et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Zhou

Cunningham

Lennon

et al. 2017

Journal of the Mechanical Behavior of Biomedical Materials

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Powder-based inkjet three-dimensional printing (3DP) to fabricate pre-designed 3D structures has drawn increasing attention. However there are intrinsic limitations associated with 3DP technology due to the weak bonding within the printed structure, which significantly compromises its mechanical integrity. In this study, calcium sulphate ceramic structures demonstrating a porous architecture were manufactured using 3DP technology and subsequently post-processed with a poly (ε-caprolactone) (PCL) coating. PCL concentration, immersion time, and number of coating layers were the principal parameters investigated and improvement in compressive properties was the measure of success. Interparticle spacing within the 3DP structures were successfully filled with PCL material. Consequently the compressive properties, wettability, morphology, and in vitro resorption behaviour of 3DP components were significantly augmented. The average compressive strength, Young's modulus, and toughness increased 217%, 250%, and 315%, following PCL coating. Addition of a PCL surface coating provided long-term structural support to the host ceramic material, extending the resorption period from less than 7 days to a minimum of 56 days. This study has demonstrated that application of a PCL coating onto a ceramic 3DP structure was a highly effective approach to addressing some of the limitations of 3DP manufacturing and allows this advanced technology to be potentially used in a wider range of applications.

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Section: Discussionmentioning

confidence: 99%

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Zhou

Cunningham

Lennon

et al. 2017

Journal of the Mechanical Behavior of Biomedical Materials

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“…One of the most relevant limitations of the model has to do with the shape of the ossification front. Usually, it adopts an irregular shape (see for example Berglundh et al (2003); Götz et al (2004)), whereas our model predicts the formation of an ossification front with a more regular shape. This is the result of contemplating in the model only the in-…”

mentioning

confidence: 84%

Bone ingrowth on the surface of endosseous implants. Part 1: Mathematical model

Moreo

García-Aznar

Doblaré

2009

Journal of Theoretical Biology

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“…Since titanium and its alloys can be directly connected to living remodeling bones at the light microscopic level, i.e., osseointegration, 1,2) they have been widely used in dental and medical implants. In fact, almost all dental implants are made of commercially pure titanium (CP-Ti) or þ type titanium alloys such as Ti-6Al-4V.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Calcium Phosphate Coating Films on Titanium Fabricated Using RF Magnetron Sputtering

et al. 2007

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Calcium phosphate coating films fabricated on commercially pure titanium (CP-Ti) substrates using radiofrequency (RF) magnetron sputtering were evaluated in vivo and in vitro for investigating their applications in dental and medical implants. For the in vitro evaluations of the calcium phosphate coating films, the bonding strength and alkaline phosphatase (ALP) activity were examined. The bonding strength of the coating films to a polished titanium plate exceeded 60 MPa. When compared with an uncoated titanium plate, the increase in the ALP activity of SaOS-2 cells (a well-characterized osteosarcoma human cell line exhibiting osteoblast-like properties) on a titanium plate coated with a calcium phosphate film was confirmed by a culture test. Titanium cylinders coated with an amorphous calcium phosphate film were implanted into the mandibles of beagle dogs. The percentage of bone-implant contact in coated titanium was greater than that in uncoated titanium.

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Effect of surface finish on the osseointegration of laser-treated titanium alloy implants

Cited by 214 publications

References 28 publications

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Bone ingrowth on the surface of endosseous implants. Part 1: Mathematical model

Evaluation of Calcium Phosphate Coating Films on Titanium Fabricated Using RF Magnetron Sputtering

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