Effect of supplementation of calcium and Vitamin D on bone mineral density and bone mineral content in peri- and post-menopause womenA double-blind, randomized, controlled trial

DANIELE, N; Carbonelli, Marco; Candeloro, N; Iacopino, L; DELORENZO, A; Andréoli, A.

doi:10.1016/s1043-6618(04)00145-8

Cited by 47 publications

(17 citation statements)

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“…People of lower socioeconomic status have a higher risk of osteoporosis (Gu, Rennie, Lin, Wang, & Yu, ; Myong, Kim, Choi, & Koo, ; Wang & Dixon, ), and those living in rural areas might have insufficient healthcare facilities, educational materials, and access to health resources. Previous studies of osteoporosis in Korea and other countries have mainly focused on hospital‐ and clinic‐based or urban populations (Di Daniele et al, ; Gu et al, ; Majumdar et al, ). Most health facilities, healthcare specialists, and high‐tech healthcare services are concentrated in urban areas.…”

Section: Discussionmentioning

confidence: 99%

“…Lifestyle changes with positive effects on bone health include education (Chan, Ko, & Day, ), exercise (Bolton et al, ; Kamide, Shiba, & Shibata, ; Korpelainen, Keinnen‐Kiukaanniemi, Heikkinen, Vnnen, & Korpelainen, ), dietary modification (Moschonis, Katsaroli, Lyritis, & Manios, ; Park, Lee, Kuller, & Cauley, ), and supplementation (Di Daniele et al, ).…”

mentioning

confidence: 99%

“…Despite the clear evidence for lifestyle change to prevent osteoporosis, postmenopausal Korean women show poor knowledge, self‐efficacy, and health behaviors related to osteoporosis (Oh, Yoo, Lee, Ko, & Chu, ; Shin, Lim, Sung, Myung, & Kim, ; Shin, Choi, et al, ). Only a few researchers have studied osteoporosis in Korea, and although beneficial effects of lifestyle changes on bone health have been reported, most intervention studies were tests of a single component of TLM, with outcome measures focused on physiologic markers of bone health (Bolton et al, ; Di Daniele et al, ; Moschonis et al, ). It is generally believed that knowledge, self‐efficacy, and health behaviors are the key elements in facilitating lifestyle modifications, but the pathways through which a comprehensive TLM program is linked to better outcomes in Korean postmenopausal women remain unclear.…”

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confidence: 99%

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Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

Yoo

Lee

et al. 2014

Res Nurs Health

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In this randomized controlled trial, we examined the effects of a 3-month therapeutic lifestyle modification (TLM) intervention on knowledge, self-efficacy, and health behaviors related to bone health in postmenopausal women in rural Korea. Forty-one women ages 45 or older were randomly assigned to either the intervention (n = 21) or control (n = 20) group. The intervention group completed a 12-week, 24-session TLM program of individualized health monitoring, group health education, exercise, and calcium-vitamin D supplementation. Compared with the control group, the intervention group showed significant increases in knowledge and self-efficacy and improvement in diet and exercise after 12 weeks, providing evidence that a comprehensive TLM program can be effective in improving health behaviors to maintain bone health in women at high risk of osteoporosis.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

Yoo

Lee

et al. 2014

Res Nurs Health

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“…Thus, we cannot know if the lack of effect on fracture risk in the RECORD trial might be related to pretreatment levels of vitamin D and/or calcium. The hierarchy of evidence for the role of vitamin D in BMD [102][103][104][105][106][107][108][109][110][111][112][113][114][115][116][117] changes and fracture reduction is given in Table 2.…”

Section: Skeletal Consequences Of Vitamin D Inadequacymentioning

confidence: 99%

High Prevalence of Vitamin D Inadequacy and Implications for Health

Holick

2006

Mayo Clinic Proceedings

1,735

1,366

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During the past decade, major advances have been made in vitamin D research that transcend the simple concept that vitamin D is Important for the prevention of rickets in children and has little physiologic relevance for adults. Inadequate vitamin D, in addition to causing rickets, prevents children from attaining their genetically programmed peak bone mass, contributes to and exacerbates osteoporosis in adults, and causes the often painful bone disease osteomalacia. Adequate vitamin D is also important for proper muscle functioning, and controversial evidence suggests it may help prevent type 1 diabetes mellitus, hypertension, and many common cancers. Vitamin D inadequacy has been reported in approximately 36% of otherwise healthy young adults and up to 57% of general medicine inpatients in the United States and in even higher percentages in Europe. Recent epidemiological data document the high prevalence of vitamin D inadequacy among elderly patients and especially among patients with osteoporosis. Factors such as low sunlight exposure, age-related decreases in cutaneous synthesis, and diets low in vitamin D contribute to the high prevalence of vitamin D inadequacy. Vitamin D production from cutaneous synthesis or intake from the few vitamin D-rich or enriched foods typically occurs only intermittently. Supplemental doses of vitamin D and sensible sun exposure could prevent deficiency in most of the general population. The purposes of this article are to examine the prevalence of vitamin D inadequacy and to review the potential implications for skeletal and extraskeletal health.

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“…Uluslararası geniş katılımlı bir çalışmada postmenopozal osteoporotik kadınların %71'inde D vitamini yetersizliği bulunmuştur (26). D vitamini ile birlikte kalsiyum alımının osteoporozu önlediği ve KMD değerlerini arttırdığı gösterilmiştir (27)(28). Osteoporoz riski altında veya osteoporozu olan kadınlara kalsiyumla birlikte D vitaminin önerilmesi ve 25-OHD seviyelerinin 30 ng/ml üzerinde tutulması Kutsal …”

Section: Discussionunclassified

Postmenopozal Osteoporotik Kadınlarda Giyim Tercihlerinin D Vitamini ve Kemik Mineral Dansiteleri Üzerine Etkisi

Kutsal

Özgüçlü

Karahan

2012

tod

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Amaç: D vitamini eksikliği osteomalazi, osteoporoz, myalji, kas güçsüzlüğü ve düşme kırık riskini arttırması nedeniyle önemli bir halk sağlığı problemidir. Giyim tercihleri D vitamini sentezi ve kan seviyelerini etkilemektedir. Bizim çalışmamızın amacı, postmenopozal osteoporotik kadınlarda giyim tercihlerinin kan serum D vitamini düzeyleri ve kemik mineral dansitesi üzerine etkisini araştırmaktır. Gereç ve Yöntemler: Çalışmamıza osteoporoz tanısı almış 55 kadın hasta dahil edildi. Bu hastalar giyim tercihlerine göre örtülü olanlar ve olmayanlar olarak iki gruba ayrıldı. Hastaların menopoz, dual energy x-ray absorptiometry sonuçları, kan kalsiyum, fosfat, paratiroid hormon, 25hydroxyvitamin D seviyeleri ve osteoporoz tedavileri kaydedildi. Bulgular: 25-hydroxyvitamin D seviyeleri anlamlı olarak örtülü giyim tercihinde olan kadınlarda daha düşük bulundu (17,0±7,9 ng/ml örtülü giyim tercihli hastalar, 33,9±22,0 ng/ml örtülü olmayan giyim tercihli hastalar, p<0,001). 25-hydroxyvitamin D seviyeleri ile femur boyun Z-skoru, femur total kemik mineral dansitesi, femur total T-skoru, L1-L4 kemik mineral dansitesi, femur boyun kemik mineral dansitesi arasında farklı mevsimlerde istatistiksel olarak anlamlı korelasyon bulundu (p<0,05). Sonuç: Postmenopozal osteoporotik örtülü giyim tercihi olan kadınlar D vitamini eksikliğine daha yatkın bulunmuştur. Düşük kan serum 25hydroxyvitamin D seviyeleri azalmış kemik mineral dansitesine eşlik edebilir. Postmenopozal osteoporotik örtülü giyim tercihi olan kadınlarda düşük kan serum 25-OHD seviyelerine rağmen, giyim tercihi ile kemik mineral dansitesi arasında bir korelasyon bulunamamıştır. (Türk Os te opo roz Dergisi 2011;17:85-8) Anah tar ke li me ler: D vitamini, giyim tercihi; osteoporoz; menopoz Summary ÖzetOrijinal Araştırma / Original Investigation 85 Aim: Vitamin D deficiency is one of the most important public health problems as a result of osteomalacia, osteoporosis, muscle pain disease, muscle weakness and increased risk of falls and fracture. Outfitting style effects the synthesis and blood levels of vitamin D. The aim of our study is to investigate the effect of outfitting style on blood vitamin D and bone mineral density in postmenopausal osteoporotic women. Materials and Methods: Fifty-five female patients who were diagnosed with osteoporosis were included in our study. These women were divided into two groups according to their clothing habits as veiled and unveiled. Data of all patients about menopause, exposure to sun light, dual energy x-ray absorptiometry results, blood calcium, phosphate, parathyroid hormone, 25-hydroxyvitamin D levels and osteoporosis treatment were recorded. Results: We found 25-hydroxyvitamin D level was significantly low in women with veiled dressing style (17,0±7,9 ng/ml in veiled and 33.9±22.0 ng/ml in unveiled patients, p<0.001). There was statistically significant correlations between 25-hydroxyvitamin D level and femur neck Z-scores, femur total bone mineral density, femur total T-score L1-L4 bone mineral density, femur neck bone minera...

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Effect of supplementation of calcium and Vitamin D on bone mineral density and bone mineral content in peri- and post-menopause womenA double-blind, randomized, controlled trial

Cited by 47 publications

References 0 publications

Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

Effects of a Three-Month Therapeutic Lifestyle Modification Program to Improve Bone Health in Postmenopausal Korean Women in a Rural Community: A Randomized Controlled Trial

High Prevalence of Vitamin D Inadequacy and Implications for Health

Postmenopozal Osteoporotik Kadınlarda Giyim Tercihlerinin D Vitamini ve Kemik Mineral Dansiteleri Üzerine Etkisi

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