Effect of Supplementary Lysine and Methionine on Enteritis Mortality, Growth and Feed Efficiency in Young Rabbits

Casady, R. B.; Damon, R. A.; Suitor, A. E.

doi:10.1093/jn/74.2.120

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…The mortality varies from 7,0 (Casady, Damon & Suitor, 1961) to 61,2% (Greenham, 1962); some breeds are said to be less susceptible than others, e.g. Jesperson & Hansen (1946-49) found that Angora rabbits were less susceptible to enteric disease than some other breeds.…”

Section: The Clinical Diseasementioning

confidence: 99%

A review of non-specific enteritis in the rabbit

Whitney

1976

Lab Anim

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Section: The Clinical Diseasementioning

confidence: 99%

A review of non-specific enteritis in the rabbit

Whitney

1976

Lab Anim

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“…Limited increases in Lys and Met concentrations in broiler diets can improve feed conversion, body weight, carcass yield, and breast muscle production [ 24 ]. In rabbits, meanwhile, dietary Lys and Met supplementation was reported to not be effective at lowering the incidence of enteritis in rabbits, but led to a significant increase in the weaning weight of young animals [ 25 ]. Similarly, in this study, we found that diets containing the 0.80% Lys/0.40% Met composition promoted the greatest average daily gain in rabbits and also significantly improved feed conversion.…”

Section: Discussionmentioning

confidence: 99%

Effects of the SLC38A2–mTOR Pathway Involved in Regulating the Different Compositions of Dietary Essential Amino Acids–Lysine and Methionine on Growth and Muscle Quality in Rabbits

Zhang

Ning

Chen

et al. 2022

Animals

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In recent years, ensuring food security has been an important challenge for the world. It is important to make good use of China’s domestic local feed resources to provide safe, stable, efficient, and high–quality rabbit meat products for China and the world. Lysine and methionine are the two most limiting essential amino acids in the rabbit diet. However, little is known about the rational composition of lysine and methionine in rabbit diets and the mechanisms that affect growth and development. Accordingly, in this study, we sought to address this knowledge gap by examining the effects of different compositions of lysine and methionine in rabbit diets. Subsequently, the growth status, nitrogen metabolism, blood biochemical indexes, muscle development, muscle quality, and the growth of satellite cells were evaluated in the animals. The results showed that diets containing 0.80% Lys and 0.40% Met improved average daily weight gain, feed conversion, nitrogen use efficiency, and muscle quality in the rabbits (p < 0.05). Additionally, it altered the amino acid transport potential in muscle by upregulating the expression of the SLC7A10 gene (p < 0.05). Meanwhile, the cell viability and the rate of division and migration of SCs in the 0.80% Lys/0.40 % Met composition group were increased (p < 0.05). SLC38A2 and P–mTOR protein expression was upregulated in the 0.80% lysine/0.40% methionine composition group (p < 0.05). In conclusion, 0.80% Lys/0.40% Met was the most suitable lysine and methionine composition in all tested diets. SLC38A2 acted as an amino acid sensor upstream of mTOR and was involved in the 0.80% Lys/0.40% Met regulation of muscle growth and development, thus implicating the mTOR signaling pathway in these processes.

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Opportunistic bacteria isolated from the caecum of rabbits with mucoid enteritis

McLeod

Katz

1986

British Veterinary Journal

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Effect of Supplementary Lysine and Methionine on Enteritis Mortality, Growth and Feed Efficiency in Young Rabbits

Cited by 6 publications

References 7 publications

A review of non-specific enteritis in the rabbit

A review of non-specific enteritis in the rabbit

Effects of the SLC38A2–mTOR Pathway Involved in Regulating the Different Compositions of Dietary Essential Amino Acids–Lysine and Methionine on Growth and Muscle Quality in Rabbits

Opportunistic bacteria isolated from the caecum of rabbits with mucoid enteritis

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