Effect of Standing on Proteinuria in Renal Disease

Sharma, B B; Gandhi, V C; Pillay, VeerasamyK.G.; Smith, Earl C.; Dunea, George

doi:10.1016/s0140-6736(71)92209-4

Cited by 9 publications

(5 citation statements)

References 8 publications

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“…A mean decrease in GFR of 18 and 28% in erect lordosis has been observed in patients with orthostatic proteinuria by King and Baldwin (7) and Robinson and colleagues (9) respectively. Furthermore, creatinine clearance has also been found to decrease markedly in the erect position in a series of patients with different parenchymal renal diseases (10), and in hypertensive patients during upright tilting (11).…”

Section: Discussionmentioning

confidence: 92%

“…The influence of postural changes on renal function has been studied previously by a number of workers (4)(5)(6)(7)(8)(9)(10)(11). However, it is difficult to carefully compare the results of these studies because of the different techniques and varied experimental conditions employed by these workers.…”

Section: Discussionmentioning

confidence: 99%

“…However, renal ptosis is at times treated by nephropexy without considering the real influence of this condition on renal function. In fact, while there are many contributions concerning the influence of postural changes on renal function in normal subjects, and in patients with different parenchymal renal diseases (4)(5)(6)(7)(8)(9)(10)(11), little data is available on renal function in patients with nephroptosis.…”

mentioning

confidence: 99%

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Influence of Postural Changes on the Glomerular Filtration Rate in Nephroptosis

Bianchi¹,

Bonadio²,

Andriole³

1976

Nephron

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Influence of Postural Changes on the Glomerular Filtration Rate in Nephroptosis

Bianchi¹,

Bonadio²,

Andriole³

1976

Nephron

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“…. 0 ing in most patients with severe or mild proteinuria (Sharma et al, 1971;Mahurkar et al, 1973) and also when some of the haemodynamic effects of standing were simulated by the application of venous tourniquets to the thighs in the supine position (Gandhi et al, 1971). Our present results are in line with the findings in these studies though at variance with those of others (Robinson et al, 1964;Relman et al, 1971;Rennie, 1971).…”

Section: Discussionmentioning

confidence: 99%

Relationship of posture and age to urinary protein excretion.

Mahurkar¹,

Dunea²,

Pillay³

et al. 1975

BMJ

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712BRITISH MEDICAL JOURNAL 29 mARicH 1975 in reducing blood pressure. The latter warrants further study in hypertensive patients.Tolamolol is a potent anti-anginal agent, preferable to practolol, and as effective as propranolol, but unlike propranolol it has the advantage of being cardioselective. journal, 1975, 1, 712-714 Summary The influence of posture and age on urinary protein excretion was studied in 120 normal men volunteers. The supine excretion rate was less than 140 Fg/min in all but two people (median value 38 ,ug/min) and tended to increase with age. The excretion rate decreased on quiet standing in 80% of people, which corresponded to a fall in creatinine clearance. In the remaining 20% protein excretion increased on standing but generally remained within normal limits and was dissociated from changes in creatinine clearance. This increase was more prevalent in younger people and may represent a phenomenon analogous to orthostatic proteinuria, differing only quantitatively.

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“…ing in most patients with severe or mild proteinuria (Sharma et al, 1971;Mahurkar et al, 1973) and also when some of the haemodynamic effects of standing were simulated by the application of venous tourniquets to the thighs in the supine position (Gandhi et al, 1971). Our present results are in line with the findings in these studies though at variance with those of others (Robinson et al, 1964;Relman et al, 1971;Rennie, 1971).…”

mentioning

confidence: 99%