712BRITISH MEDICAL JOURNAL 29 mARicH 1975 in reducing blood pressure. The latter warrants further study in hypertensive patients.Tolamolol is a potent anti-anginal agent, preferable to practolol, and as effective as propranolol, but unlike propranolol it has the advantage of being cardioselective. journal, 1975, 1, 712-714 Summary The influence of posture and age on urinary protein excretion was studied in 120 normal men volunteers. The supine excretion rate was less than 140 Fg/min in all but two people (median value 38 ,ug/min) and tended to increase with age. The excretion rate decreased on quiet standing in 80% of people, which corresponded to a fall in creatinine clearance. In the remaining 20% protein excretion increased on standing but generally remained within normal limits and was dissociated from changes in creatinine clearance. This increase was more prevalent in younger people and may represent a phenomenon analogous to orthostatic proteinuria, differing only quantitatively.