Effect of soybean oil on the production of mycelial biomass and pleuromutilin in the shake-flask culture of Pleurotus mutilis

Abstract

Effect of soybean oil on mycelial biomass and pleuromutilin biosynthesis by Pleurotus mutilis-04 was investigated in shake flask culture. The maximum pleuromutilin production and mycelial biomass were 8.32 ± 0.02 g l -1 and 49.

Carbon source regulation of antibiotic production

“…186 Compared with glucose as the sole carbon source, soybean oil was beneficial for pleuromutilin production in shaker flask cultures. 187 This result suggested a suppressive effect of glucose on antibiotic production.…”

Nutrient regulation of bacterial growth and production of anti-tumor metabolites in Stigmatella WXNXJ-B fermentation

“…A 3 ml sample was removed from each flask. The samples were diluted with water until the final OD 600 reading was less than 0.2 (Regentin et al 2003).The biomass was measured as the dry weight per unit volume according to the report by Hu et al (2009). About 5 ml of fermentation broth was centrifugated at 220g for 10 min to remove the solid materials of the medium.…”