Response spectrum is considered one of the main tools in seismic design of structural systems. However, for short return period earthquakes, such spectra have not been studied in details. These spectra are needed, particularly, in the construction industry for determination of the required level of strength and stiffness for the structures during construction. In this work, using probabilistic seismic hazard analysis, short return period spectra for two geographical regions with high and moderate level of seismic intensities are developed. According to the results of this study, large distant earthquakes have significant contribution in defining the amplitude and frequency contents of short return period spectra in the regions with moderate seismicity and soft soils. The results also show that, in the regions with moderate seismicity, such spectra are about 30% wider in the frequency range of short and middle height buildings if they compare with those developed for high seismicity regions.