Zinc treatment significantly reduces duration of fever and very ill status in boys, but not in girls, with severe ALRI. Vitamin A treatment of children with severe ALRI had no significant beneficial effect.
SUMMARYThis paper presents a simple procedure for modifying the dynamic coupled soil-pore fluid equations in a manner which allows a stable and efficient staggered solution procedure to be used. The solution method is simpler than an alternative suggested by Park" and has a direct physical interpretation. This stabilized procedure is efficient in numerical time domain analysis of soil-pore fluid occurring in earthquake and consolidation problems. Numerical examples of one and two dimensional saturated poroelastic media demonstrate the procedure.
Both the doses of LGG (10(10) and 10(12) CFU) were equally effective to decrease the frequency and duration of diarrhea and reduction in hospital stay in patients of AWD.
Enteric fever, caused by Salmonella enterica, remains an unresolved public health problem in India and antimicrobial therapy is the main mode of treatment. The objective of this study was to characterize the Salmonella enterica isolates from Kolkata with respect to their antimicrobial resistance (AMR), virulence profiles and molecular subtypes. Salmonella enterica blood isolates were collected from clinically suspected enteric fever patients attending various hospitals in Kolkata, India from January 2009 to June 2013 and were tested for AMR profiles by standard protocols; for resistance gene transfer by conjugation; for resistance and virulence genes profiles by PCR; and for molecular subtypes by Pulsed Field Gel Electrophoresis (PFGE). A total of 77 Salmonella enterica serovar Typhi (S. Typhi) and 25 Salmonella enterica serovar Paratyphi A (S. Paratyphi A) from Kolkata were included in this study. Although multidrug resistance (resistance to chloramphenicol, ampicillin, co-trimoxazole) was decreasing in S. Typhi (18.2%) and absent in S. Paratyphi A, increased resistance to fluoroquinolone, the current drug of choice, caused growing concern for typhoid treatment. A single, non-conjugative non-IncHI1 plasmid of 180 kb was found in 71.4% multidrug resistant (MDR) S. Typhi; the remaining 28.6% isolates were without plasmid. Various AMR markers (bla
TEM-1, catA, sul1, sul2, dfrA15, strA-strB) and class 1 integron with dfrA7 gene were detected in MDR S. Typhi by PCR and sequencing. Most of the study isolates were likely to be virulent due to the presence of virulence markers. Major diversity was not noticed among S. Typhi and S. Paratyphi A from Kolkata by PFGE. The observed association between AMR profiles and S. Typhi pulsotypes might be useful in controlling the spread of the organism by appropriate intervention. The study reiterated the importance of continuous monitoring of AMR and molecular subtypes of Salmonella isolates from endemic regions for better understanding of the disease epidemiology.
SUMMARYThe general forms for the field equations governing the transient response of poroelastic media given by Biot and by Zienkiewicz are compared and relations between the material constants are obtained. A one-dimensional analytical solution is presented for the situation where the solid and fluid materials satisfy Biot's dynamic compatibility relation. The transient response of porous media is illustrated for varying degrees of solid and fluid compressibility when subjected to step, cyclic and short duration spike surface tractions. The results obtained (for the special situation where the materials are dynamically compatible) exhibit the overall characteristics of wave propagation in porous media and will provide representative test problems which allow a quantitative evaluation of the accuracy of various numerical solution methods (e.g. finite element models).
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