Effect of Smooth Pulsed Light at 400 to 700 and 870 to 1,200 nm for Acne Vulgaris in Asian Skin

Kawana, Seiji; Tachihara, Rieko; Kato, Tokue; Omi, Tokuya

doi:10.1111/j.1524-4725.2009.01380.x

Cited by 41 publications

(26 citation statements)

References 30 publications

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“…Sung et al reported that more than 63% of the study cases improved when IPL was used [7] . Kawana et al reported that IPL had a satisfactory effect on acne vulgaris in Asians [8] . Yeung et al reported a 43% reduction in acne when IPL was used [9] .…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of intense pulsed light in the treatment of mild-to-moderate acne vulgaris

2017

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Acne vulgaris is a very common chronic inflammatory disease of pilosebaceous units. It can be associated with considerable loss of self-esteem and psychological morbidity when left untreated. With the emergence of lasers and intense pulsed light, long-term reduction of acne lesions is now possible. The success of these optical devices depends on the selected parameters and biologic variables of patient. The objective of this study is to determine the efficacy and safety of intense pulsed light (IPL) in the treatment of mild-to-moderate acne vulgaris. This interventional study was conducted for a period of one year after approval of synopsis. A total of 75 patients of mild-to-moderate acne vulgaris were included through non-probability, convenience sampling. Patients were subjected to intense pulsed light (IPL) therapy once a week for four weeks. Digital photography was done at the baseline and at the sixth week. Follow-up was done after two weeks of completion of four sessions. Repeated measurement ANOVA was used for significance of IPL at six weeks of follow-up. The p value < 0.05 was taken as significant. IPL was effective in 52% of the patients. Out of all cases, 6 (8%) showed excellent results. 33 (44%) showed >50% reduction with therapy. Percentage reduction was observed as 49% ± 20% at final follow-up. Papules count was reduced from 11.95 ± 2.89 to 6.69 ± 2.96, pustules count was reduced from 2.55 ± 1.54 to 0.79 ± 1.02 from baseline to final follow-up visit. 16 subjects showed mild erythema that resolved within 24 h. None of the patients showed any severe side effects at final follow-up visit. We conclude from the results of this study that IPL is safe and efficacious in more than half of the patients in the treatment of mild and moderate acne vulgaris. A long-term follow-up is required to determine long-term safety on skin following such procedures.Keywords: Acne vulgaris; intense pulsed light; pustules; papules Citation: Khan WZ, Butt G, Altaf F. Efficacy and safety of intense pulsed light in the treatment of mild-to-moderate acne vulgaris. J Surg Dermatol 2017; 2(T1): 152-157; http://dx

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Section: Introductionmentioning

confidence: 99%

Efficacy and safety of intense pulsed light in the treatment of mild-to-moderate acne vulgaris

2017

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“…Mild erythema was noted in two patients which resolved with appropriate treatment. However, in study done by Kawana s et al; 20 out of 25 patients, twenty patients experienced immediate erythema, nineteen of them reported burning or stinging, which disappeared within a few days. Crusting, bulla formation and hyperpigmentation were observed in four, one and two patients respectively but these resolved within 1 to 2 weeks.…”

Section: Discussionmentioning

confidence: 99%

“…A study conducted by Kawana S et al 20 reported the mean percentage reduction in noninflammatory acne lesions being 87.1% and the mean percentage reduction in inflammatory acne lesion was 88.3% after five treatment sessions of IPL. In our study at the end of 6 treatment sessions (6 weeks), the mean percentage reduction in total lesion count was 74.1% from baseline.…”

Section: Discussionmentioning

confidence: 99%

Normative data of median nerve conduction in the state of Haryana

2020

IJN

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Introduction: Acne vulgaris is a self-limiting, chronic inflammatory disorder of pilosebaceous follicle seen commonly among young adults with significant psychological and social impact. Multiple topical and systemic therapies targeting various pathogenic factors of acne are available, in spite of which patients are unable to achieve adequate and long term control of acne. Therefore, there is a need for newer therapeutic modalities that are more effective, convenient and safe. In this regard, one of the emerging treatment modalities is intense pulse light (IPL) therapy which meet the need for novel acne treatment. Objectives: To evaluate the efficacy and safety of intense pulse light (IPL) therapy in the treatment of facial acne vulgaris. Materials and Methods: A total of 30 patients in age group of 18-40 years with facial acne vulgaris meeting the defined inclusion and exclusion criteria were enrolled in this study after taking an informed consent and approval of institutional ethical committee. All the patients with facial acne vulgaris grade 1-4 were subjected to monotherapy with IPL. Convention fluence of 10 J and 410 nm cut off filter was used at first sitting. IPL was administered weekly for 6 weeks, and the fluence was increased by 1 J every session. Acne severity assessment was done at initial visit (week 0) and at the end of last treatment session (week 6) based on Michaelssons acne severity index. Also at the initial visit, at each sitting and at the end of final treatment session (6 sessions), lesions count (counting the number of comedones, papules, pustules, cysts and nodules) were undertaken. Percentage reduction in the number of lesions were calculated at each visit and at end of final treatment session (6th session) and graded as mild (0-25%), moderate (26-50%), good (51-75%), and excellent (76-100%) improvement relative to baseline. Results: At the end of 6 treatment sessions (6 weeks), the mean percentage reduction of non-inflammatory, inflammatory and total lesion counts were 60.2%, 80.4%, 74.1% relative to baseline respectively. Mean Michaelssons acne severity index at baseline (0 week) was 50.83 and at the end of six treatment sessions was 10.20. The improvement in acne severity score was found to be statistically significant (p=.000). No significant adverse effects were noticed. Conclusion:The results of this study show that IPL is effective and safe for management of facial acne vulgaris grade 1 -4 with minimal reversible side effects.

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“…[40] Current studies using IPL as an anti-acne therapy have led to mixed results. Kanwna et al, [41] evaluated the efficacy and safety of IPL on acne vulgaris in Asian skin in 25 patients. He showed short-term improvement in both inflammatory and non-inflammatory acne lesions using IPL alone.…”

Section: Intense Pulsed Lightmentioning

confidence: 99%

Laser and light based treatments of acne

Rai¹,

Natarajan²

2013

Indian J Dermatol Venereol Leprol

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Medical treatments for acne vulgaris include a variety of topical and oral medications. Poor compliance, lack of durable remission, and potential side effects are common drawbacks to these treatments. Therefore, there is a growing demand for a fast, safe, and side-effect-free novel therapy. Acne often improves after exposure to sunlight, and this has led to the development of laser and other light therapies resulting in the overall ease of treatment, with minimal adverse effects. A variety of light and laser devices has been used for the treatment of acne, including the potassium titanyl phosphate laser, the 585- and 595-nm pulsed dye lasers, the 1450-nm diode laser, radiofrequency devices, intense pulsed light sources, and photodynamic therapy using 5-aminolevulinic acid and indocyanine green. These devices are thought to target the underlying pathogenic factors such as propionibacterium acnes colonization, increased sebaceous gland activity, and the cutaneous inflammatory response. In this article, we review the current status of light- and laser-based treatment of acne.

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Effect of Smooth Pulsed Light at 400 to 700 and 870 to 1,200 nm for Acne Vulgaris in Asian Skin

Abstract: IPL with dominant wavelengths of 400 to 700 nm had a satisfactory effect on acne vulgaris in Asians.

Cited by 41 publications

References 30 publications

Efficacy and safety of intense pulsed light in the treatment of mild-to-moderate acne vulgaris

Efficacy and safety of intense pulsed light in the treatment of mild-to-moderate acne vulgaris

Normative data of median nerve conduction in the state of Haryana

Laser and light based treatments of acne

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