Laser and light based treatments of acne

Rai, Reena; Natarajan, Karthika

doi:10.4103/0378-6323.110755

Cited by 44 publications

(55 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The major factors in the pathogenesis of acne are increased sebum production, hypercornification of pilosebaceous duct, abnormality of the microbial flora, especially ductal colonization with Propionibacterium acnes and inflammation [4].…”

mentioning

confidence: 99%

Intense pulsed light: A promising therapy in treatment of acne vulgaris

Puttaiah¹,

Jartarka²

2017

Our Dermatol Online

View full text Add to dashboard Cite

mentioning

confidence: 99%

Intense pulsed light: A promising therapy in treatment of acne vulgaris

Puttaiah¹,

Jartarka²

2017

Our Dermatol Online

View full text Add to dashboard Cite

“…13,14 In IPL during photothermolysis, the endogenous chromophores in the skin absorb broad spectrum light delivered by IPL which creates enough heat and energy to damage blood vessels supplying sebaceous glands, thus reduce sebum production. 15 Anti-inflammatory effect of IPL is through down regulation of TNF-α and upregulation of transforming growth factor-beta1 (TGF-β1)/smad signaling. 16,17 In our study the mean lesion count of noninflammatory (comedones) lesions progressively decreased at the end of each treatment session with IPL (6 sessions).…”

Section: Discussionmentioning

confidence: 99%

Normative data of median nerve conduction in the state of Haryana

2020

IJN

View full text Add to dashboard Cite

Introduction: Acne vulgaris is a self-limiting, chronic inflammatory disorder of pilosebaceous follicle seen commonly among young adults with significant psychological and social impact. Multiple topical and systemic therapies targeting various pathogenic factors of acne are available, in spite of which patients are unable to achieve adequate and long term control of acne. Therefore, there is a need for newer therapeutic modalities that are more effective, convenient and safe. In this regard, one of the emerging treatment modalities is intense pulse light (IPL) therapy which meet the need for novel acne treatment. Objectives: To evaluate the efficacy and safety of intense pulse light (IPL) therapy in the treatment of facial acne vulgaris. Materials and Methods: A total of 30 patients in age group of 18-40 years with facial acne vulgaris meeting the defined inclusion and exclusion criteria were enrolled in this study after taking an informed consent and approval of institutional ethical committee. All the patients with facial acne vulgaris grade 1-4 were subjected to monotherapy with IPL. Convention fluence of 10 J and 410 nm cut off filter was used at first sitting. IPL was administered weekly for 6 weeks, and the fluence was increased by 1 J every session. Acne severity assessment was done at initial visit (week 0) and at the end of last treatment session (week 6) based on Michaelssons acne severity index. Also at the initial visit, at each sitting and at the end of final treatment session (6 sessions), lesions count (counting the number of comedones, papules, pustules, cysts and nodules) were undertaken. Percentage reduction in the number of lesions were calculated at each visit and at end of final treatment session (6th session) and graded as mild (0-25%), moderate (26-50%), good (51-75%), and excellent (76-100%) improvement relative to baseline. Results: At the end of 6 treatment sessions (6 weeks), the mean percentage reduction of non-inflammatory, inflammatory and total lesion counts were 60.2%, 80.4%, 74.1% relative to baseline respectively. Mean Michaelssons acne severity index at baseline (0 week) was 50.83 and at the end of six treatment sessions was 10.20. The improvement in acne severity score was found to be statistically significant (p=.000). No significant adverse effects were noticed. Conclusion:The results of this study show that IPL is effective and safe for management of facial acne vulgaris grade 1 -4 with minimal reversible side effects.

show abstract

“…Various forms of phototherapy with visible light have been shown to be effective in the treatment of acne vulgaris [9]. Treatments using light within the blue range have been found to be particularly effective in the selective destruction of P. acnes bacterium.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Self-Treatment of Acne Using Silk’n Blue Phototherapy System

Hellman¹,

Ramirez²

2014

JCDSA

View full text Add to dashboard Cite

Background: At-home phototherapy devices for the treatment of acne have emerged as an appealing treatment option and as an effective adjunct treatment to existing modalities. The principal goal of the study was to determine the changes in the number of inflammatory lesions in acne patients. Methods: Patients received instruction for daily at-home use of Silk'n Blue device for 12 weeks. Follow-up visits were conducted at 1 and 3 months to collect data. Results: Fifteen subjects with mild to severe cases experienced improvement over the course of the trial. The decrease in mean inflammatory acne counts (from 41.26 to 24.46) and mean percent reduction (41.8%) were statistically significant (p < 0.001). Some participants experienced percent reductions as great as 67%. No adverse events were recorded. Conclusions: The Silk'n Blue device is a safe and effective modality for at-home treatment of mild, moderate, and severe inflammatory acne vulgaris with proper use.

show abstract

Laser and light based treatments of acne

Cited by 44 publications

References 52 publications

Intense pulsed light: A promising therapy in treatment of acne vulgaris

Intense pulsed light: A promising therapy in treatment of acne vulgaris

Normative data of median nerve conduction in the state of Haryana

Evaluation of Self-Treatment of Acne Using Silk’n Blue Phototherapy System

Contact Info

Product

Resources

About