Effect of simplified Tai Chi exercise on relieving symptoms of patients with mild to moderate Parkinson's disease

Zhu, Mingjin; Zhang, Yonghua; Pan, Jiafei; Fu, Changyong; Wang, Yaqun

doi:10.23736/s0022-4707.19.10104-1

Cited by 36 publications

(54 citation statements)

References 42 publications

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“…Some studies have shown that some lifestyle interventions could improve the quality of life of PD patients, such as behavior therapy, sleep improvement, mood improvement, and physical exercise (2)(3)(4)(5). However, few studies have examined the effect of nutritional status on the quality of life of patients with PD (6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors for Malnutrition in Patients With Parkinson's Disease

et al. 2020

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Objectives: This study aimed to investigate the relationship between nutritional status and Parkinson's disease (PD) features.Methods: The cohort was composed of 556 Parkinson's patients who were admitted to the hospital. Patients were categorized as normal nutrition or at risk of malnutrition/already malnourished. Questionnaires, physical examinations, and biochemical tests were conducted. The relationship between nutrition status and PD was analyzed using t-tests, χ2-tests, and logistic regression models.Results: The prevalence of malnutrition [defined as a Mini Nutritional Assessment (MNA) score <17] was 39.2%, and 30.3% of patients were at risk of malnutrition (17 ≤ MNA score ≤ 23.5). There was no difference in gender and age between the different nutrition groups (P < 0.05). Patients at risk of malnutrition and those who were malnourished had a longer course of disease, more severe motor symptoms, a higher stage of PD according to the Hoehn and Yahr (H-Y) classification, a lower body mass index (BMI) index, a lower cognitive score, higher levels of depression and anxiety, and more serious non-motor symptoms (P < 0.05) than patients with normal nutrition. There were differences in adenosine deaminase, albumin, phosphorus, chlorine, total protein, and uric acid between the two groups (P < 0.05). High Unified PD Rating Scale (UPDRS-III) scores, high H-Y stages, and dyskinesia were risk factors for malnutrition in PD patients, while high levels of total protein, uric acid, and chlorine were protective factors that led to good nutrition (P < 0.05).Conclusions: Our results showed that dyskinesia, disease severity, total protein levels, uric acid levels, and chlorine levels were associated with nutritional status among Chinese PD patients. The findings of this study indicate the significance of the early detection and prevention of malnutrition to improve the quality of life of PD patients.

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Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors for Malnutrition in Patients With Parkinson's Disease

et al. 2020

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“… The scheme of neuroprotective and neuroinflammatory factors in PD’s. Based on animal and clinical trial studies [ 120 , 138 , 140 , 146 , 147 , 151 - 153 ] the selected factors may influence on neuroprotection or neuroinflammation in reducing or worsening Parkinson’s decrease. (A) The proper diet combined with regular physical activity can lead to neuroprotection and consequently lowering the markers of inflammation and free radicals damage of macromolecules, improving the function of mitochondria as well as reducing the risk of osteoporosis, which is associated with decreasing risk of falls.…”

Section: The Beneficial Effect Of Selected Physical Activity In Pdmentioning

confidence: 99%

The Proper Diet and Regular Physical Activity Slow Down the Development of Parkinson Disease

Chromiec¹,

Urbaś²,

Jacko³

et al. 2021

Aging and disease

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From year to year, we know more about neurodegeneration and Parkinson’s disease (PD). A positive influence of various types of physical activity is more often described in the context of neuroprotection and prevention as well as the form of rehabilitation in Parkinson’s patients. Moreover, when we look at supplementation, clinical nutrition and dietetics, we will see that balancing consumed products and supplementing the vitamins or minerals is necessary. Considering the biochemical pathways in skeletal muscle, we may see that many researchers desire to identify molecular mediators that have an impact through exercise and balanced diet on human health or development of the neurodegenerative disease. Therefore, it is mandatory to study the potential mechanism(s) related to diet and factors resulted from physical activity as molecular mediators, which play a therapeutic role in PD. This review summarizes the available literature on mechanisms and specific pathways involved in diet-exercise relationship and discusses how therapy, including appropriate exercises and diet that influence molecular mediators, may significantly slow down the progress of neurodegenerative processes. We suggest that a proper diet combined with physical activity will be a good solution for psycho-muscle BALANCE not only in PD but also in other neurodegenerative diseases.

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“…While the two treatment groups discussed above (Hackney & Earhart, 2009) did not improve on the UPDRS, the control group performed worse at post-test than a pre-test, after the period of no-treatment. One possible explanation for why dancing was beneficial for PD is that the treatment increased physical fitness, which is correlated with symptom reduction in PD as assessed using the UPDRS (Zhu et al, 2019). To tease apart the different mechanisms by which dance could affect PD, more evidence is needed to link music and rhythmic stimulation specifically to gains in the disease severity of PD, and methodologically these findings underline the utility of standardized pre- and post-intervention measures on all treatment and control arms of the intervention.…”

Section: Targeting Specific Brain Networkmentioning

confidence: 99%

Neuroscientific Insights for Improved Outcomes in Music-based Interventions

Loui

2020

Music & Science

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Music therapy is an evidence-based practice, but the needs and constraints of various stakeholders pose challenges towards providing the highest standards of evidence for each clinical application. First, what is the best path from clinical need to multi-site, widely adopted intervention for a given disease or disorder? Secondly, how can we inform policy makers that what we do matters for public health––what evidence do we have, and what evidence do we need? This article will review the multiple forms of evidence for music-based interventions in the context of neurological disorders, from large-scale randomized controlled trials (RCT) to smaller-scale experimental studies, and make the case that evidence at multiple levels continues to be necessary for informing the selection of active ingredients of interest in effective musical interventions. The current article reviews some of the existing literature on music-based interventions for neurodegenerative disorders, with particular focus on neural structures and networks that are targeted by specific therapies for disorders including Alzheimer’s Disease, Parkinson’s Disease, and aphasia. This is followed by a focused discussion of principles that are gleaned from studies in cognitive and clinical neuroscience, which may inform the active ingredients of music-based interventions. Therapies that are driven by a deeper understanding of the musical elements that target specific disease mechanisms are more likely to succeed, and to increase the chances of widespread adoption. The article closes with some recommendations for future research.

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Effect of simplified Tai Chi exercise on relieving symptoms of patients with mild to moderate Parkinson's disease

Cited by 36 publications

References 42 publications

Prevalence and Risk Factors for Malnutrition in Patients With Parkinson's Disease

Prevalence and Risk Factors for Malnutrition in Patients With Parkinson's Disease

The Proper Diet and Regular Physical Activity Slow Down the Development of Parkinson Disease

Neuroscientific Insights for Improved Outcomes in Music-based Interventions

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