Effect of short-term treatment with bovine somatotropin at estrus on conception rate and luteal function of repeat-breeding dairy cows

Morales-Roura, J.S.; Zarco, L.; Hernández-Cerón, Joel; Rodríguez, Guadalupe Carrión

doi:10.1016/s0093-691x(01)00525-8

Cited by 40 publications

(46 citation statements)

References 33 publications

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“…This outcome may be due to the unintended selection of subfertile cows with subsequent inseminations (repeat breeders) (Morales-Roura et al 2001). This coincides with observations by Roque et al (2016) who also found that pregnancy rate was higher in first service cows than in cows serviced after 150 days in milk.…”

Section: Resultssupporting

confidence: 85%

Pregnancy rate in dairy cows treated with human chorionic gonadotropin five days after insemination

González¹,

Pérez²,

Garza³

et al. 2017

Austral j. vet. sci.

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ABSTRACT. This study tested whether the administration of hCG five days after insemination increased progesterone concentration and pregnancy rate (PR) in dairy cows. A total of 989 lactating Holstein cows with different parity and number of prior services were used. Cows were inseminated after overt estrus or at a fixed-time. Five days post-insemination, cows were randomly assigned to two treatment groups: hCG (n=482), which received 3500 IU of hCG by intramuscular injection; and the control group (n=507), which did not receive any treatment. Pregnancy was diagnosed by ultrasound on day 30 post-insemination, and gestation was confirmed on day 60 post-insemination by rectal palpation. In 15 cows from each treatment group, plasma progesterone concentration was determined on days 5, 11, and 15 post-insemination. Pregnancy rate was analysed using logistic regression. Variations in progesterone concentration between treatments were tested by ANOVA for repeated measurements. Progesterone concentration was higher on days 11 and 15 in cows treated with hCG, compared to the control group (P<0.05). Treatment with hCG increased pregnancy rate (47.5 vs. 37.4%. Odds ratio 1.3; P<0.05). No interaction was observed between treatment and body condition, prior services, milk production, parity, or insemination type (overt estrus or fixed time). Treatment with hCG did not reduce pregnancy losses between day 30 and 60 post-insemination (P>0.1). We conclude that injection of hCG five days after insemination increased progesterone concentration and pregnancy rate in dairy cows.Key words: hCG, fertility, progesterone, dairy cows. RESUMEN.Este estudio evaluó si la administración de hCG cinco días después de la inseminación incrementa la concentración de progesterona y la tasa de preñez (TP) en vacas lecheras. Se utilizaron 989 vacas Holstein de diferente número de parto y servicio. Las vacas se inseminaron después de la detección del estro o a tiempo fijo. El día cinco postinseminación las vacas se asignaron aleatoriamente a dos tratamientos: hCG (n=482), donde recibieron 3500 UI de hCG vía im; y control (n=507), donde no recibieron tratamiento. Se diagnosticó la gestación mediante ecografía el día 30 posinseminación y se confirmó el día 60 por palpación transrectal. En 15 vacas de cada tratamiento se determinó la concentración plasmática de progesterona los días 5, 11 y 15 postinseminación. Se analizó la TP mediante regresión logística y la concentración de progesterona mediante análisis de varianza. La concentración de progesterona fue más alta los días 11 y 15 en las vacas tratadas con hCG que en las control (P<0,05). El tratamiento con hCG incrementó la TP en comparación con sus controles (47,5 vs. 37,4%; odds ratio 1,3; P<0,05). No se observó interacción entre el tratamiento con la condición corporal, número de servicios, producción láctea, número de partos y el tipo de inseminación (detección de estro o tiempo fijo). El tratamiento con hCG no disminuyó la pérdida de gestaciones entre los días 30 y 60 postinseminación (P>0.1). S...

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Section: Resultssupporting

confidence: 85%

Pregnancy rate in dairy cows treated with human chorionic gonadotropin five days after insemination

González¹,

Pérez²,

Garza³

et al. 2017

Austral j. vet. sci.

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“…2007). This finding is supported by studies in which bovine somatotrophin injection at the time of insemination improved conception rates in repeat breeder cows (Morales‐Roura et al. 2001).…”

Section: Igf System and Fertilitymentioning

confidence: 63%

“…Cows with a low postpartum nadir in their IGF1 concentration take longer to resume oestrous cycles following calving and are also less likely to conceive (Butler 2003;Taylor et al 2004b;Patton et al 2007). This finding is supported by studies in which bovine somatotrophin injection at the time of insemination improved conception rates in repeat breeder cows (Morales-Roura et al 2001).…”

Section: Igf System and Fertilitymentioning

confidence: 71%

Mechanisms Linking Metabolic Status and Disease with Reproductive Outcome in the Dairy Cow

Wathes

2012

Reprod Domestic Animals

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Contents Culling for infertility remains the main reason for disposal of dairy cows, limiting productive lifespan. In extreme cases, ovulation is inhibited, preventing the possibility of conception. More often cows do conceive, but fail to remain pregnant owing to intrinsic problems in the embryo and/or to a poor‐quality reproductive tract environment. Both aspects have a genetic component and are also influenced by management practices affecting nutrition and health. The relative importance of these factors varies among heifers, first‐lactation and older cows. A common theme, however, is that an internal signalling system exists which reduces fertility when the cow is in an unsuitable metabolic state to sustain a pregnancy. This may be directly related to nutrient shortage caused by inadequate feed intake, or because available nutrients are being prioritized towards growth or milk production, away from reproduction. Evidence is presented for the involvement of the somatotrophic axis (GH, IGF1, insulin, IGFBP2) and leptin as key metabolic signalling molecules. Another emerging theme is the interaction between metabolism and disease that affects the fertility. Common examples include (i) calf diseases causing inadequate heifer growth and increased age at first calving; (ii) poor peripartum energy status reducing the capacity of the uterus to involute and mount an effective immune response, thereby increasing the likelihood of endometritis; and (iii) development of mastitis after conception, a contributory factor to both early and late embryo mortality. Finally, recent evidence suggests that times of metabolic stress cause mitochondrial damage that also contributes to a reduction in longevity.

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“…Although the incidence of repeat breeding [1][2][3][4][29][30][31], its causes [3,4,6,10,13], and treatment [15,23,[32][33][34] have already been reported, the present study is apparently the first to provide a detailed assessment of reproductive performance in repeat breeders. That their reproductive performance was poorer than in normal fertility cows was predictable a priori, based on the definition of repeat breeders.…”

Section: Discussionmentioning

confidence: 91%

Reproductive performance of repeat breeders in dairy herds

et al. 2010

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Effect of short-term treatment with bovine somatotropin at estrus on conception rate and luteal function of repeat-breeding dairy cows

Cited by 40 publications

References 33 publications

Pregnancy rate in dairy cows treated with human chorionic gonadotropin five days after insemination

Pregnancy rate in dairy cows treated with human chorionic gonadotropin five days after insemination

Mechanisms Linking Metabolic Status and Disease with Reproductive Outcome in the Dairy Cow

Reproductive performance of repeat breeders in dairy herds

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