Effect of Short-term Smoking Halt on Carboxyhemoglobin Levels and P50 Values

Acute Effects of Nicotine and Smoking on Blood Flow, Tissue Oxygen, and Aerobe Metabolism of the Skin and Subcutis

“…Seemingly, this finding may have been caused by tissue oxygen reduction as well, but carboxyhemoglobin and exhaled carbon monoxide demonstrated a significant 2-fold increase following smoking and may therefore have affected the oxygen-transporting capacity and reduced the aerobic metabolism as suggested by others [42][43][44].…”

Influence of Smoking and Alcohol Drinking Behaviors on Treatment Outcomes of Patients With Squamous Cell Carcinomas of the Head and Neck

“…Smoking increases blood carboxyhemoglobin, producing hypoxia by the decrease in loading capacity of oxygen by the hemoglobin (24). Of interest, the level of carboxyhemoglobin becomes normal 8 hours after the last cigarettes (25). If acute hypoxia is implicated in radioresistance, this may be of interest to patients unable to quit smoking, as they may then be treated early in the morning after a night of abstinence.…”

Urinary cotinine testing as pre-operative assessment of patients undergoing free flap surgery

“…That much said, it is interesting to note that patients undergoing an operation are particularly attentive to the advice put forward by their surgeons, and that an intervention consequently constitutes an excellent occasion for them to introduce themselves to a tobacco-free life. Studies have shown that even when the advice-giving period is brief (3 minutes), a surgeon's counsels can increase the rate of abstinence from smoking [17][18][19][20]. Were surgeons to adopt a more systematic and unified advisory approach, it could quite possibly lead to a pronouncedly higher rate of abstinence and markedly enhance surgical outcomes.…”

“…Given the relatively short half-life of nicotine and carbon monoxide, there are solid reasons to believe that even abstinence of short duration (a few hours, for example, or a few days) could be beneficial, particularly for cardiovascular complications [17,34]. However, some studies have suggested that weeks or even months of cessation could be required so as to limit the risk of pulmonary complications [35,36].…”