Effect of Selenium in Preventing Exudative Diathesis in Chicks

Patterson, E. L.; Mil-strey, R. A.; Stokstad, E. L. R.

doi:10.3181/00379727-95-23307

Cited by 224 publications

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“…Schwarz & Foltz (1957) demonstrated not only that the purest Factor 3 concentrates contained Se but that inorganic sodium selenite was effective, in minute doses, in preventing hepatic necrosis in rats. Simultaneously Patterson, Milstrey & Stokstad (1957) were working on the isolation, from casein or pig tissues, of a factor which prevented exudative diathesis in chicks fed upon diets containing torula yeast. Ash from concentrates, made in the presence of alkali, was protective, but ash made in the presence of acid was inactive.…”

Section: Selenium and Vitamin E In Nutritionmentioning

confidence: 99%

The history of selenium—vitamin E interrelationships

Moore

1962

Proc. Nutr. Soc.

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Research CouncilI count it both an honour and a pleasure to be invited to come 'north of the border' to give the opening paper of this Symposium. The presentation of my paper, however, will not be easy, in view of the extreme complexity of the field. Before forming a balanced opinion about the dietary importance of selenium we must know something about the mode of action of vitamin E per se. This subject was already very complicated before Se came into the story, and I could indeed occupy the whole space allotted to the printed version of my paper by giving a list of references. I cannot really do more, therefore, than deal with vitamin E itself in rough outline, and so leave time to review, only a little more fully, the recent work on Se.

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Section: Selenium and Vitamin E In Nutritionmentioning

confidence: 99%

The history of selenium—vitamin E interrelationships

Moore

1962

Proc. Nutr. Soc.

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“…The nutritional essentiality of selenium arose from the work of Patterson et al (1957) in chickens. Subsequently, it was found that vitamin E and selenium are essential for proper health, immunity and reproductive functions of animals, and their inter-relationship became an active and rewarding fi eld of research, as vitamin E and Se are the micronutrients that share a common biological function.…”

Section: Introductionmentioning

confidence: 99%

Effect of vitamin E and selenium supplementation on haematology, blood chemistry and thyroid hormones in male buffalo (<i>Bubalus bubalis</i>) calves

Shinde¹,

Dass²,

Garg³

2009

J. Anim. Feed Sci.

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An experiment was conducted on 20 male buffalo calves (average body weight 75.30 ± 2.20 kg) to elucidate the effect of supplemental vitamin E and/or selenium (Se) on their haematology, blood metabolic profi le, serum enzymes and thyroid hormones status. Group I served as control (without any supplementation), groups II, III and IV were supplemented with 0.3 mg Se, 300 IU of DL-α-tocopheryl acetate, and both 300 IU DL-α-tocopheryl acetate and 0.3 mg Se, respectively. Animals were fed on wheat straw and concentrate mixture to meet their nutrient requirements. Blood was collected at zero day and subsequently at 45, 90, 135 and 180 days and analysed for haematological parameters, blood chemistry and level of thyroid hormones. Results revealed no signifi cant difference (P>0.05) in haematological parameters (haemoglobin, packed cell volume, red blood cell, white blood cell) due to the supplementation of vitamin E ,Se or both vitamin E + Se in buffalo calves. Similarly, the concentration of various blood biochemical components (glucose, total protein, albumin, globulin, urea, creatinine, total cholesterol, and triglycerides) except high density lipid (HDL) cholesterol was statistically similar in 4 groups. Results revealed signifi cantly (P<0.01) higher concentration (mg/dl) of HDL cholesterol in buffalo calves given Se and Se + vitamin E as compared to control and vitamin E supplemented groups. There was no signifi cant difference in serum enzymes (serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase, creatine kinase and lactate dehydrogenase) activities due to different treatments. Level of triiodothyronine was signifi cantly (P<0.01) higher in buffalo calves supplemented with selenium, and vitamin E + Se, as compared to non-supplemented control group; whereas concentration of thyroxine (nmol/l) was statistically similar in 4 groups, without showing * This research work was carried out under AP Cess Fund Ad Hoc scheme supported by Indian Council of Agricultural Research, Krishi Bhawan, New Delhi (India) 1 Corresponding author: e-mail: rsd@ivri.up.nic.in Animal and Feed Sciences, 18, 2009, 241-256 242 VITAMIN E AND SE SUPPLEMENT -THYROID HORMONES IN CALVES any effect of different treatments. It may be concluded that supplementation of Se and vitamin E in the diet of buffalo calves had no benefi cial effect on blood haematology and blood chemistry except an increase in the serum levels of high density lipid cholesterol and triiodothyronine as compared to non-supplemented control buffalo calves. Journal of

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“…The essentiality of Se for animals is well known (14,23), and a role of this element as a constituent of glutathione peroxidase from animal sources (20) has been established. No conclusive evidence has been presented for a Se requirement for growth of higher plants in general or the presence of a Se-containing glutathione peroxidase (1).…”

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confidence: 99%