2015
DOI: 10.1016/j.wneu.2013.05.009
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Effect of Scalp Blocks with Levobupivacaine on Recovery Profiles After Craniotomy for Aneurysm Clipping: A Randomized, Double-Blind, and Controlled Study

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Cited by 42 publications
(66 citation statements)
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“…A previous meta‐analysis published in 2013 identified a positive impact of regional scalp block for postcraniotomy analgesia, but the RCTs included were small and of limited methodological quality . Up to now, only the 3 RCTs included in our study were performed, which seem not to provide strong evidence on scalp block analgesic efficacy . During the first 6 postoperative hours, the analgesic efficacy of scalp infiltration applied prior to surgery was superior to that performed upon skin closure, while the results from scalp block applied before awakening vs. placebo presented conflicting results, as the positive results in terms of pain and PONV control can be questioned by the equivalent overall consumption of fentanyl between groups.…”
Section: Discussionmentioning
confidence: 85%
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“…A previous meta‐analysis published in 2013 identified a positive impact of regional scalp block for postcraniotomy analgesia, but the RCTs included were small and of limited methodological quality . Up to now, only the 3 RCTs included in our study were performed, which seem not to provide strong evidence on scalp block analgesic efficacy . During the first 6 postoperative hours, the analgesic efficacy of scalp infiltration applied prior to surgery was superior to that performed upon skin closure, while the results from scalp block applied before awakening vs. placebo presented conflicting results, as the positive results in terms of pain and PONV control can be questioned by the equivalent overall consumption of fentanyl between groups.…”
Section: Discussionmentioning
confidence: 85%
“…Application of scalp block with bupivacaine 0.75% before awakening vs. placebo significantly improved pain scores, attenuated rescue analgesic needs, prolonged time to first analgesic rescue, and reduced the incidence of PONV during the 72‐hour period of assessment . However, the overall consumption of fentanyl provided as a basic analgesic agent with a PCA device was similar between groups.…”
Section: Resultsmentioning
confidence: 94%
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“…Although scalp block is usually associated with decreased postoperative opioid consumption [39] and decreased opioid-related adverse events (post-operative nausea and vomiting -PONV-among others), some studies have shown no clinical significant advantage associated with its use. Gazoni et al studied 30 patients schedule to undergo craniotomy under standard general anesthesia.…”
Section: Local Anesthesiamentioning
confidence: 99%
“…Long-acting local anaesthetics are helpful if available, such as bupivacaine (0.5%), levobupivacaine (0.5%), and ropivacaine (0.75%), which all should be supplemented with epinephrine to reduce systemic absorption and to elongate duration [23]. Furthermore, adequate scalp blocks are known to improve recovery profiles and postoperative pain [24]. We prefer the combination of rapid onset and long-acting local anaesthesia by combining bupivacaine (0.5%) and lidocaine (1%).…”
Section: Anaesthetic Management and Implicationsmentioning
confidence: 99%