Effect of saline pushing after contrast material injection in abdominal multidetector computed tomography with the use of different iodine concentrations

Tatsugami, Fuminari; Matsuki, Mitsuru; Kani, Hiroyuki; Tanikake, Masato; Miyao, Mamoru; Yoshikawa, Shushi; Narabayashi, Isamu

doi:10.1080/02841850500479636

Cited by 16 publications

(4 citation statements)

References 12 publications

(18 reference statements)

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“…Various effects of the saline chaser technique have been reported since its introduction in medical imaging. The method increases the peak attenuation, reduces the artifacts produced by contrast materials [4111314], and decreases the amount of the contrast material used during the imaging procedure [38915].…”

Section: Discussionmentioning

confidence: 99%

“…The procedure pushes the bolus further into the blood circulation, decreasing the amount of contrast material in the anatomic locations where it is not required. Therefore, accumulation of contrast material in the peripheral vein and injection tubing, which can occur with the use of MDCT and the reduced scanning time in CT imaging, is prevented by applying the saline chaser technique [56789]. Studies conducted on this topic report that reducing the amount of contrast material does not decrease vascular enhancement.…”

Section: Introductionmentioning

confidence: 99%

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Usefulness of a saline chaser to reduce contrast material dose in abdominal CT of normal dogs

et al. 2019

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Use of a saline chaser has been reported to allow reduction of contrast dose and artifacts during computed tomography (CT) examination in humans. This study assesses the extent of contrast dose by using a saline chaser in abdominal CT scans of normal dogs. Five beagles underwent abdominal CT scans. Three protocols were applied: 600 mg I/kg iohexol without saline chaser (protocol 1), 30% lower dose of iohexol (420 mg I/kg) followed by a 10 mL saline chaser (protocol 2), and 40% lower dose of iohexol (360 mg I/kg) followed by a 10 mL saline chaser (protocol 3). Attenuation values were obtained from aorta, portal vein, and liver parenchyma. The maximum enhancement values (MEVs) in protocol 2 were significantly higher than those in protocols 1 and 3 in the aorta; no difference was seen in the portal vein in all protocols. The liver parenchymal MEVs in protocols 1 and 2 were significantly higher than those obtained in protocol 3. In this study, the use of a saline chaser and a reduced dose of contrast material did not affect vessel enhancement. In conclusion, use of a saline chaser for abdominal CT of dogs is recommended because it allows a 30% reduction of contrast dose without decreasing vascular and hepatic parenchymal enhancement.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Usefulness of a saline chaser to reduce contrast material dose in abdominal CT of normal dogs

et al. 2019

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“…In the field of abdominal CT, there is little evidence of the influence of saline flushing on the vessel and parenchymal enhancement. Previous experiences (34,35) investigating the effect of saline flushing on aortic, portal, and hepatic enhancement, reported a significant increase of aortic peak and no evidence of improvement on hepatic enhancement. Another recent study (11), confirmed a non-significant increase of hepatic enhancement magnitude while finding a significant increase of portal vein enhancement during the early and late arterial phases.…”

Section: Saline Injectionmentioning

confidence: 95%

The optimal contrast media policy in CT of the liver. Part I: Technical notes

Rengo¹,

Bellini²,

Cecco³

et al. 2011

Acta Radiol

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Latest developments of multidetector computed tomography (MDCT), which is today considered a real volumetric technique, have revolutionized abdominal imaging. Technological improvements such as higher spatial resolution, larger volume coverage and higher temporal resolution, have reduced scan times allowing CT studies of the abdomen within a single breath-hold. Furthermore, the increased number of slices, the submillimetric collimation, and the use of multiple dynamic post-contrast phases per single examination, may all contribute to increase the radiation exposure of single patients. The aim of this review is to discuss different parameters affecting contrast media enhancement, as vascular enhancement, parenchymal enhancement and timing, in order to minimize the amount of contrast medium injected and the radiation exposure

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“…However, the saline volumes used in these studies varied widely from 20 to 50 ml. Furthermore, to our knowledge, there have been only a few studies regarding the volume of physiological saline used in saline flush technique [15][16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of required saline volume in dynamic contrast-enhanced computed tomography using saline flush technique

Yamaguchi

Kidoya

Suzuki

et al. 2009

Computerized Medical Imaging and Graphics

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Effect of saline pushing after contrast material injection in abdominal multidetector computed tomography with the use of different iodine concentrations

Abstract: The saline pushing technique can contribute to a decrease in contrast material concentration for 3D CT arteriography and portography.

Cited by 16 publications

References 12 publications

Usefulness of a saline chaser to reduce contrast material dose in abdominal CT of normal dogs

Usefulness of a saline chaser to reduce contrast material dose in abdominal CT of normal dogs

The optimal contrast media policy in CT of the liver. Part I: Technical notes

Evaluation of required saline volume in dynamic contrast-enhanced computed tomography using saline flush technique

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