Effect of Running on Gastroesophageal Reflux and Reflux Mechanisms

Herregods, T. V. K.; Hoeij, Froukje B. van; Oors, Jac; Bredenoord, Albert J.; Smout, A. J. P. M.

doi:10.1038/ajg.2016.122

Cited by 31 publications

(25 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Physical activity may alter TPG due to changes in both AP and TP (20) . Also, the number of TLESR seems to increase during exercise (21) . During the postprandial period, and increase in AP and TPG may be noticed (22) .…”

Section: Transdiaphragmatic Pressure Gradient In Healthmentioning

confidence: 91%

The Role of the Transdiaphragmatic Pressure Gradient in the Pathophysiology of Gastroesophageal Reflux Disease

Grande

Herbella

Katayama

et al. 2018

Arq. Gastroenterol.

View full text Add to dashboard Cite

Gastroesophageal reflux disease (GERD) is the most common disease of the upper gastrointestinal tract in the Western world. GERD pathophysiology is multifactorial. Different mechanisms may contribute to GERD including an increase in the transdiaphragmatic pressure gradient (TPG). The pathophysiology of GERD linked to TPG is not entirely understood. This review shows that TPG is an important contributor to GERD even when an intact esophagogastric barrier is present in the setting of obesity and pulmonary diseases.

show abstract

Section: Transdiaphragmatic Pressure Gradient In Healthmentioning

confidence: 91%

The Role of the Transdiaphragmatic Pressure Gradient in the Pathophysiology of Gastroesophageal Reflux Disease

Grande

Herbella

Katayama

et al. 2018

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

“…Central obesity measured by abdominal visceral adipose tissue volume, but not BMI or waist circumference, was associated with EE. Recent studies have suggested that running or abdominal compression as a mechanical factor is correlated with GERD, and results of combined high-resolution pH measurement and manometry should be used (11,18).…”

Section: Discussionmentioning

confidence: 99%

Association Between Erosive Esophagitis and the Anthropometric Index in the General Korean Population

Kim

2019

Balkan Med J

View full text Add to dashboard Cite

Background: An association between obesity and gastroesophageal reflux disease has been reported. However, previous studies have focused on obesity or central obesity. Aims: To investigate the association of the anthropometric index and endoscopic erosive esophagitis in health checkups of Koreans. Study Design: Case-control study. Methods: A total of 1.207 consecutive subjects (aged 40-80 years) during health checkups underwent upper endoscopy and bioelectrical impedance analysis. We collected anthropometric data by bioelectrical impedance analysis, which consisted of body mass index, percent body fat, muscle mass, and fat mass. Results: Of 1.207 subjects who underwent upper gastrointestinal endoscopy (mean age, 50.55±9 years), 239 (19.8%) had endoscopic erosive esophagitis. In a univariate analysis, the endoscopic erosive esophagitis group was more likely to be a male and had a higher body mass index, muscle mass and fat mass. In logistic regression analysis, only muscle mass remained an independent risk factor for EE after adjustment for both age and gender. Higher muscle mass was associated with increased EE risk (rate ratio: 1.354, 95% confidence interval: 1.206-1.405, p= 0.027). Conclusion: High muscle mass, but body mass index, is an independent risk factor for erosive esophagitis in a population over 40 years of age.

show abstract

“…Symptoms of GERD account for most upper gastrointestinal symptoms in healthy athletes and worsen with the intensity of physical activity and during postprandial activity. Especially during high intensity workout [maximal oxygen uptake (VO 2 max) >90%], the number and duration of reflux episodes increase by decreased esophageal motility, decreased pressure of the lower esophageal sphincter ( 22 , 23 ), increased intraabdominal pressure, decreased intestinal blood flow, and body positioning ( 22 , 23 ). Aerobic training improves all of these these mechanisms.…”

Section: Discussionmentioning

confidence: 99%

Physical Fitness and Locomotor Skills in Children With Esophageal Atresia-A Case Control Pilot Study

König

Muensterer

2018

Front. Pediatr.

View full text Add to dashboard Cite

Background: Patients with esophageal atresia (EA) often experience physical limitations. With increasing survival over the past decades, the focus in care shifted toward improving the long-term quality of life. We performed validated testing fitness and motor skills in children born with EA.Methods: Patients with EA were evaluated using the standardized Kinderturntest Plus/ Deutscher Motorik Test after caregiver's written consent. Test scores range from 1 to 5 (compared to an age- and gender matched standard population). Caregivers completed an online-questionnaire on patient history.Results: Seventeen patients (median age 7 [3–12] years) were included. Comorbidities were prematurity (54%), birth weight <1,500 g (23%), congenital heart disease (46%), developmental delay (38%), skeletal deformity (23%), and anorectal malformation (15%). The mean test score was significantly lower in children with EA (2.19) compared to a control group matched for age, gender, body weight, and –height, (2.75, p = 0.04), and the general population (3, p = 0.00). Distribution of patient scores was below the 41st performance percentile for gender and age in 54–63%. Caregivers identified notable deficits of strength and endurance. All but one patient complained about discomfort during physical exercise, most commonly respiratory distress (46%) and gastroesophageal reflux symptoms (31%). Notably, 93% of subjects participated in regular school physical education classes, and 86% participated regularly in additional organized sporting activities.Conclusions: Children after EA repair have decreased physical fitness and impaired locomotor function compared to the general population on a standardized test. Physical discomfort is frequent during exertion. To avoid demotivation, locomotor skill should be promoted at each individual's comfortable level.The study was registered at www.researchregistry.com (No. 3707).

show abstract

Effect of Running on Gastroesophageal Reflux and Reflux Mechanisms

Cited by 31 publications

References 29 publications

The Role of the Transdiaphragmatic Pressure Gradient in the Pathophysiology of Gastroesophageal Reflux Disease

The Role of the Transdiaphragmatic Pressure Gradient in the Pathophysiology of Gastroesophageal Reflux Disease

Association Between Erosive Esophagitis and the Anthropometric Index in the General Korean Population

Physical Fitness and Locomotor Skills in Children With Esophageal Atresia-A Case Control Pilot Study

Contact Info

Product

Resources

About