Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: A randomized, triple-blind, placebo-controlled study

Taavoni, S.; Barkhordari, F; Goushegir, Ashrafeddin; Haghani, Hamid

doi:10.1016/j.ctim.2014.05.004

Cited by 37 publications

(26 citation statements)

References 18 publications

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“…The first investigated royal jelly and found that it facilitates the premenstrual syndrome [75]. Participants in this study took 1 g of royal jelly on a daily basis.…”

Section: Apitherapeutic Recommendations For the Treatment Of Primary mentioning

confidence: 99%

Meaningfulness of Apitherapeutic Approaches Using the Example of Primary Dysmenorrhoea

Münstedt¹

2018

J Apither

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“…The first investigated royal jelly and found that it facilitates the premenstrual syndrome [75]. Participants in this study took 1 g of royal jelly on a daily basis.…”

Section: Apitherapeutic Recommendations For the Treatment Of Primary mentioning

confidence: 99%

Meaningfulness of Apitherapeutic Approaches Using the Example of Primary Dysmenorrhoea

Münstedt¹

2018

J Apither

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“…The 4T1 tumor closely mimics human breast cancer with regards to anatomically correct site, immunogenicity and (18,19). Therefore, the 4T1 tumor is a suitable model for testing the therapy effects under experimental conditions.…”

Section: Introductionmentioning

confidence: 99%

The effect of royal jelly on the growth of breast cancer in mice

et al. 2017

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Abstract. Due to various pharmacological properties, including antioxidative, anti-inflammatory and antibiotic properties, royal jelly (RJ) has been widely consumed in daily diets in numerous countries. In the present study, the effect of RJ on 4T1-bearing mice was investigated. The study was performed by feeding 4T1-bearing mice with RJ using either the prophylactic-therapeutic (PTRJ) or therapeutic (TRJ) method. The experimental results for the PTRJ group demonstrated that the weight of tumor was significantly reduced (RJ 0.5 and 1.5 g/kg); and in the serum, the levels of interleukin (IL)-2 (RJ 0.5 and 1.5 g/kg), interferon (IFN)-α, superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) were significantly elevated, but the concentrations of IL-4 (RJ 0.5 and 1.5 g/kg) and IL-10 (RJ 1.0 g/kg) were significantly decreased. In addition, the activities of T-AOC and glutathione reductase (GR) were significantly improved in the liver, whereas in the kidney, the activities of T-AOC and GR were significantly increased only under the dose of 0.5 g/kg. For the TRJ group, the antitumor effect of RJ was not significant; the change in IL-2, IFN-α, SOD and T-AOC levels in the serum, and the change in T-AOC and GR in liver were similar to those observed in the PTRJ groups. RJ treatment was demonstrated to reduce the development of breast tumor in mice, and simultaneously improve the antioxidant capacity of the serum, liver and kidney, particularly using the prophylactic-therapeutic method. These results corroborated the efficacy of RJ supplementation in diets. The results of the present study suggest that the antioxidant and immunomodulatory activities of RJ serve an important role on antitumor growth.

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“…Some studies about complications of these treatments showed misuse of SSRIs and an increased risk of suicide attempts in young girls, and also the risk of hypertension before the age of 40 among women who use hormonal drugs to get rid of symptoms [16,17]. So, it has been suggested to find non-chemical and non-hormonal alternatives [18]. Many women seek natural alternatives because of the side effects of synthetic drugs.…”

Section: Introductionmentioning

confidence: 99%

<b><i>Salvia officinalis</i></b> Reduces the Severity of the Premenstrual Syndrome

et al. 2018

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Background: This study aims to investigate the effects of Salvia officinalis on the severity of the premenstrual syndrome (PMS). Methods: This was a triple-blinded randomized clinical trial on 90 college students in Tehran, Iran. The participants were randomly divided into 2 groups who were treated with 500-mg Salvia officinalis capsules or placebo once a day for 2 consecutive months. Data were collected using a questionnaire and a daily form for recording symptoms of PMS. Results: The mean decreases in severity of the symptoms in the Salvia officinalis extract-treated group during the first and second months after treatment were 19.84% and 23.42%, respectively. The comparison of the PMS physical and psychological symptoms demonstrated a decrease following treatment in both groups, with more remarkable reduction in the Salvia officinalis group (p < 0.001). Conclusion: Salvia officinalis is an effective alternative agent to reduce the severity of psychological and physical symptoms of PMS.

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Effect of Royal Jelly on premenstrual syndrome among Iranian medical sciences students: A randomized, triple-blind, placebo-controlled study

Cited by 37 publications

References 18 publications

Meaningfulness of Apitherapeutic Approaches Using the Example of Primary Dysmenorrhoea

Meaningfulness of Apitherapeutic Approaches Using the Example of Primary Dysmenorrhoea

The effect of royal jelly on the growth of breast cancer in mice

<b><i>Salvia officinalis</i></b> Reduces the Severity of the Premenstrual Syndrome

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