Effect of Rosa canina L. (Rose-hip) on cold during winter season in a middle-class population: A randomized, double-blinded, placebo-controlled trial

Winther, Kaj; Warholm, Lina; Campbell-Tofte, Joan; Marstrand, Kristian

doi:10.1016/j.hermed.2018.04.003

Cited by 3 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A significant reduction in the inflammatory marker-erythrocyte sedimentation rate (ESR) was also observed in the test group of a placebo-controlled study, where 5 gram of the same R. canina species was administered to rheumatoid patients for 6 months [61]. It is interesting to note that in these two studies, administration of a preparation composed of only the shells of rose hip did not cause significant changes in CRP levels [62,63].…”

Section: Can Administration Of Rose Hips Improve the Immune System?mentioning

confidence: 96%

“…In conclusion: It seems that rose hip can modify lipid metabolism. This can possibly be related to the shells as shell-only powders [62,66] as well as combined shell/seed powders [60,67] were able to improve the lipid profile. Such declines were not observed when testing a seed only product in high concentration (personal communication, Kaj Winther).…”

Section: Can Rose Hip Treatment Impact Cardiovascular Disease Hyperli...mentioning

confidence: 99%

“…Seeds from rose hip contain high amounts of polyunsaturated fatty acids, among them omega-3 and omega-6. Omega 3 and omega 6 acids [69] possibly supported by certain antioxidants may explain why rose hip powders containing also seeds [59][60][61] show more anti-inflammatory property than shells-only products [62,63,66]. It has not been possible to find any indications of an impact from any version of rose hip on glucose metabolism in humans although a few animal studies look promising.…”

Section: Can Rose Hip Treatment Impact Cardiovascular Disease Hyperli...mentioning

confidence: 99%

“…In a study on rheumatoid arthritis, there was a significant reduction in sedimentation rate, an inflammatory marker [61]. Again, no such changes in inflammatory markers were seen testing shells-only powders [62,63]. From the insight we have today, it seems that a certain molecule, a galactolipid named GOPO, which acts as an anti-inflammatory agent, is important [95].…”

Section: Effect Of Rose Hip On Arthrosis and Rheumatoid Arthritismentioning

confidence: 99%

See 3 more Smart Citations

Rose Hip as a Nutraceutical

Lustrup¹,

Winther²

2022

Medicinal Plants

Self Cite

View full text Add to dashboard Cite

From ancient times, rose hip has been used as food source and as part of herbal remedies. Modern research has confirmed that rose hip, especially when containing seeds and shells, reduces pain and improves daily activity in animal models and in patients with osteoarthritis. The effect size on pain is comparable to that observed with nonsteroidal anti-inflammatory agents and superior to that obtained with paracetamol. For example, treatment with a subspecies of Rosa canina (Lito) resulted in 50% reduction in intake of pain killers. There are also strong indications that conditions such as rheumatoid arthritis, aging skin, and wrinkles benefit from treatment with rose hip. Cardiovascular diseases, especially where hyperlipidemia plays a major role, can be treated with rose hip, since a modest reduction of blood cholesterol levels as well as kidney and liver protection has been reported with the treatment. Variation in efficacy and amount of active ingredients in the different species, as well as with different ways of production, should be recognized. Rose hip can be collected from nature. It takes 5–7 Rosa canina berries to produce the daily dose of 5 gram of mixed shell-seed powder.

show abstract

Section: Can Administration Of Rose Hips Improve the Immune System?mentioning

confidence: 96%

Section: Can Rose Hip Treatment Impact Cardiovascular Disease Hyperli...mentioning

confidence: 99%

Section: Can Rose Hip Treatment Impact Cardiovascular Disease Hyperli...mentioning

confidence: 99%

Section: Effect Of Rose Hip On Arthrosis and Rheumatoid Arthritismentioning

confidence: 99%

See 2 more Smart Citations

Rose Hip as a Nutraceutical

Lustrup¹,

Winther²

2022

Medicinal Plants

Self Cite

View full text Add to dashboard Cite

show abstract

Phytochemical Composition of Lipophilic Fraction of Plants of the Plant Rosa Canina L. Genus Rosa

Ikhsanov

Tasmagambetova²,

Litvinenko

et al. 2020

Series Chemistry and Technology

View full text Add to dashboard Cite

The genus of wild rose, or Rosa L., belongs to the family Rosaceae. It has many cultural forms, bred under the general name Rosa. At the moment, more than 400 species of rose hips are known. Usually these are upright shrubs, less often creepers, sometimes low tree-like forms or almost herbaceous plants. Rosehip is common in the temperate and subtropical zones of the Northern Hemisphere, it can often be found in the mountainous regions of the tropical zone. Some species of rose hips are common from the Arctic Circle in the north to Ethiopia in the south. On the American continent - from Canada to Mexico, Favorable conditions for Rosehip are in the Mediterranean region. Several species of the Rosehip genus have an extensive distribution area. Kazakhstan has significant resources of medicinal raw materials of plant origin. Among the most priority representatives of the wild flora are species of the rosehip genus - Rosa L. as a most valuable medicinal plant. In total, 21 species of wild rose grow in the republic, including 5 in the central Kazakhstan: R. glabrifolia - sh. naked, R. laxa Retz. - w. loose, R. acicularis Lindl. - (W. needlefish), R. majalis Herrm. (R. cinnamomea L.) - sh. May (W. cinnamon) and R. pimpinellifolia L. (R. spinosissima L.) - W. femoral cell. Kazakhstan species of the genus Rosa L. Rose hips are characterized by a high content of biologically active substances and are widely used both in medicine and in cooking. In this paper, a comparative analysis of rose hips, Rosa canina L., harvested in the fall of 2018 is carried out. Plant raw materials are collected in the southern region of the Republic of Kazakhstan (Almaty region). The crushed air-dry raw materials were extracted with hexane and chloroform in the ratio of raw materials-reagent (1:10) in a Soxhlet apparatus. The resulting extract was concentrated under mild conditions to a thick concentrate, which was analyzed on a gas chromatograph with a mass selective detector. The analyzes were carried out on a gas chromatograph with a mass spectrometric detector 6890N / 5973C (Agilent, USA). The peaks detected in the chromatograms were identified using the NIST’11 and Wiley 10 mass spectral libraries. The article first studied and conducted a comparative analysis of lipophilic substances contained in the fruits of the plant Rosa canina L, harvested in the Almaty region. The extracts mainly include hydrocarbons, derivatives of higher carboxylic acids, higher alcohols and some other substances, in particular butyl tetradecyl ether of hydrochloric acid, [4- (2-methylpentanoylsulfamoyl) phenyl] amide of 2-methylpentanoic acid in hexane extract and, butyl undecyl ether sulfuric acid, eicosyl trifluoroacetate and ethoxycarbonyl-3-methyl-4-azafluorenone, 2-fluorenilim in the chloroform extract. Further work will be continued in order to determine the potential biological activity of the obtained extracts. Keywords: Rosa canina L., СКФ-экстракция, никотин, GC-MS, химический состав.

show abstract