Effect of Rinsing with Phosphorylated Chitosan on Four-day Plaque Regrowth.

Abstract

This clinical investigation examined the effect of phosphorylated chitosan rinsing on plaque development and on the buffering capacity of plaque suspension. Three male adult subjects participated in the trial that was designed as a single blind study. Participants refrained from mechanical oral hygiene procedures during a four-day study and rinsed three times a day with 20 ml of test solutions. A wash-out period of three days was instituted between the placebo and phosphorylated chitosan rinsing period. Clinical evaluation and plaque sampling were performed at the end of each test period. We disclosed plaque accumulations on the buccal upper front teeth with a two-tone disclosing agent to distinguish between newly formed plaque and old plaque. After taking color slides, we then used a computerized image analysis. Tooth areas covered by plaque on the color slides were digitized and expressed as percentages of the tooth area. The buffering capacity of the collected plaque fluid was determined by using a beta-titrator. A mouth rinse containing 0.5% phosphorylated chitosan significantly reduced both newly formed plaque areas (red disclosed; p < 0.001) and old plaque areas (blue disclosed; p < 0.01) compared to a placebo rinsing. However there was no significant difference in the plaque buffering capacity (p > 0.05) between the mouth rinse containing 0.5% phosphorylated chitosan and placebo. These findings might suggest that mouth rinse containing phosphorylated chitosan would be effective in reducing plaque formation and have a slight ability to enhance plaque buffering capacity.

Chitosan 2% Effect on Prohibiting the Growth of Candida Albicans on Heatcured Acrylic Resin

“…Belum pernah dilakukan pengujian efektifitas antimikroba dan antifungi larutan kitosan sebagai bahan perendam gigi tiruan sebagian lepasan. [10][11][12][13] Berdasarkan latar belakang dan uraian tersebut di atas maka penulis melakukan pengujian efek antifungi larutan chitosan pada resin akrilik heatcured. Chitosan memiliki sifat antifungi karena memiliki gugus aktif yang akan berikatan dengan mikroorganisme.…”

Chitosan impregnated gutta-percha points: antimicrobialin vitroevaluation and mechanical properties

“…Chitosan showed antibacterial properties against oral bacterial pathogens [22][23][24][25] . Furthermore, recent studies demonstrated that water-soluble reduced chitosan, used as a mouth rinse solution, displayed an antibacterial and plaque-reducing action [26][27][28][29] . Chewing gum containing chitosan and chitosan derivatives, also effectively inhibited the growth of cariogenic bacteria in saliva [30][31][32] .…”

A study to assess the efficacy of a new detergent free, whitening dentifrice in vivo using QLF planimetric analysis

“…9 The purpose of this trial is to investigate the effect of SLS removal and the incorporation of whitening agents on the plaque inhibitory action of the paste using a well-accepted plaque regrowth model. [10][11][12] Plaque measurement There are a multitude of plaque indices available to researchers examining products or therapies, to detect, measure and describe the plaque effects of such interventions. Indices in current use generally estimate plaque quantity by either the area of tooth covered or the thickness of the plaque in the area measured.…”