Effect of rice bran on intraintestinal fermentation and cholesterol metabolism in cecectomized rats

Fukushima, Michihiro; Fujii, Satoko; Yoshimura, Yumi; Endo, Tamao; Nakano, Masahiro

doi:10.1016/s0271-5317(98)00187-0

Cited by 11 publications

(6 citation statements)

References 21 publications

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“…We therefore determined the organic acid concentrations involving SCFA in the intestinal contents, and found that feeding the OBFR diet markedly increased the concentrations of acetic acid, butyric acid, and propionic acid. This is in agreement with the earlier studies showed that feeding diet containing rice bran markedly increases in intestinal SCFA in rats [29,30]. Furthermore, 95% of the SCFAs produced in the cecum and large intestine are rapidly absorbed by colonocytes [31][32][33][34], and SCFAs have reportedly been found in hepatic, portal, and peripheral blood [35,36].…”

Section: Discussionsupporting

confidence: 92%

Feeding the Outer Bran Fraction of Rice Alters Hepatic Carbohydrate Metabolism in Rats

et al. 2020

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Dietary intake of fiber-rich food has been reported to contribute to multiple health benefits. The aim of the current study is to investigate the effects of a diet containing the outer bran fraction of rice (OBFR), which is rich in insoluble fiber, on the intestinal environment and metabolite profiles of rats. Fourteen 8-week-old male Sprague–Dawley rats were divided into a control group and an OBFR group. For a period of 21 days, the control group was fed a control diet, while the OBFR group was fed a diet containing 5% OBFR. Metabolomics analysis revealed drastic changes in the cecal metabolites of the rats fed the OBFR diet. Furthermore, in the plasma and liver tissue, the concentrations of metabolites involved in pyruvate metabolism, the pentose phosphate pathway, gluconeogenesis, or valine, leucine, isoleucine degradation were changed. Concordantly, the OBFR diet increased the expression of genes encoding enzymes involved in these metabolic pathways in the livers of the rats. Collectively, these results suggest that the OBFR diet altered the concentrations of metabolites in the cecal contents, plasma, and liver, and the hepatic gene expressions of rats, and that this may have mainly contributed to carbohydrate metabolism in the liver.

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Section: Discussionsupporting

confidence: 92%

Feeding the Outer Bran Fraction of Rice Alters Hepatic Carbohydrate Metabolism in Rats

et al. 2020

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“…2). This is similar to that of earlier studies (Ambuhl et al 1979;Williams & Senior 1982;Ohta et al 1994;Nagata et al 1996;Fukushima et al 1999). However, this significant difference was not recognized in the latter half of the experiment, that is, the feed intake of the cecectomized rats was not significantly different to that of the control rats during this period.…”

Section: Discussionsupporting

confidence: 90%

Effects of cecectomy on digestion and retention time of digesta in rats

Kurosawa

Ikeda

Hagiwara

et al. 2007

Animal Science Journal

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The present experiment aimed to obtain basic knowledge of the role of the cecum in the digestion of protein, fiber and energy, and in the retention of digesta in rats. Twelve healthy male Sprague–Dawley strain rats were used. The experiment lasted for 8 weeks following preliminary feeding. Crude protein [CP], acid detergent fiber [ADF], and energy digestibilities were measured in weeks 1, 4, and 7 of the experiment, while the digesta retention time was measured in weeks 2, 5, and 8. At the end of the test, the colon capacity was measured after killing the rats with diethyl ether. The effects of the cecectomy were not recognized in bodyweight gain, even while the feed intake was high and the feed efficiency was low due to the cecectomy. However these effects were not recognized in the latter half of the test periods. The mean retention time of digesta for the cecectomized rats was about 2 h shorter than that for the control group of rats, while the retention time of digesta in week 8 increased compared to weeks 2 and 5. The digestibility of each substance was significantly lower following the cecectomy. The colon became swollen because of the cecectomy and this swollen colon made up for the capacity of the dissected cecum. It had been considered that the cecum does not play a role in the digestion of nutrition for growth, however, the present results showed two types of effects of cecectomy: one that disappears in accordance with time after surgery (i.e. feed intake and feed efficiency), and another that continues for a longer period (i.e. digestibility, retention time of digesta).

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“…RBO consists of approximately 38% oleic, 34% linoleic, 1% myristic, 22% palmitic, 3% stearic, and 2% a-linolenic acids. Crude RBO is also good source of g-oryzanol (1.6%) which offers many health benefits, such as ability to lower plasma cholesterol by reducing cholesterol absorption, decrease early atherosclerosis, inhibit platelet aggregation, and decrease fecal bile excretion (Ausman et al, 2005;Fukushima, Fujii, Yoshimura, Endo, & Nakano, 1999).…”

Section: Introductionmentioning

confidence: 99%

Development of shrikhand premix using microencapsulated rice bran oil as fat alternative and hydrocolloids as texture modifier

Gupta

Jadhav

2015

Food Hydrocolloids

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Effect of rice bran on intraintestinal fermentation and cholesterol metabolism in cecectomized rats

Cited by 11 publications

References 21 publications

Feeding the Outer Bran Fraction of Rice Alters Hepatic Carbohydrate Metabolism in Rats

Feeding the Outer Bran Fraction of Rice Alters Hepatic Carbohydrate Metabolism in Rats

Effects of cecectomy on digestion and retention time of digesta in rats

Development of shrikhand premix using microencapsulated rice bran oil as fat alternative and hydrocolloids as texture modifier

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