Effect of remained stem height on yield, quality of Inula helenium I. and on soil water content

Abstract

To explore the reason causing low yield, poor quality of , this paper investigated the influence of different remained stem heights on the yield, quality and water consumption of in Gannan plateau area using field single factor randomized block method. Research results showed that which was cut before blooming period in the last ten-day of July with remained stem height of 25 cm had the lowest water consumption, the best underground root traits (including main root length, root diameter, and root dry weight per plant), and the highest yield which was higher that control group by 18.73% (P< .01) Moreover, with remained stem height of 25 cm had the lowest ash content while the highest content, therefore its quality was the best. The water use efficiency (WUE) of with remained stem height of 35 cm at September was the highest (1.12 kg⋅h⋅m⋅mm). However, in terms of biological yield WUE and economic yield WUE, with remained stem height of 15 cm was the highest. Therefore, it can be concluded that remained stem height from 15 to 25 cm is an ideal solution, which can not only save water, but also improve yield and quality of

Alantolactone-Loaded Pegylated Prodrug Nanocarriers for Synergistic Treatment of Cisplatin-Resistant Ovarian Cancer via Reactivating Mitochondrial Apoptotic Pathway

“…Alantolactone (AL), one of the significant sesquiterpene lactone compounds, is isolated from the root of Inula Helenium L and has a variety of biological activities, such as anti-inflammatory, antimicrobial, and especially anticancer activities. , AL can inhibit the activity of TrxR1, increase the level of ROS in cancer cells, and oxidatively damage cancer cells, which may reverse the reduction and detoxification mechanisms of Pt-based chemotherapeutics. − Meanwhile, AL can induce mitochondrial membrane potential (Δψ m ) depolarization and mitochondrial dysfunction by inhibiting the activity of TrxR1 to increase the level of ROS, which reactivates the mitochondrial apoptotic pathway and potentially reverses the apoptosis-blocking mechanism. , However, AL is unstable due to its rapid metabolism, limited solubility, and low bioavailability, which limit its further development in clinical applications.…”

Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

“…ALT, a major bioactive sesquiterpene component of Inula helenium, has been reported to possess multiple biological and pharmacological properties including antibacterial, antifungal, anti-in ammatory and anticancer effects [7]. In recent years, ALT has been reported to exert anti-tumor effects in several types of cancer, including lung cancer, gastric cancer, hepatic cancer, B-cell acute lymphoblastic leukemia, pancreatic cancer and breast cancer [8].…”

Alantolactone inhibits cell autophagy and promotes apoptosis through targeting AP2M1 in acute lymphotic leukemia

“…ALT, a major bioactive sesquiterpene component of Inula helenium, has been reported to possess multiple biological and pharmacological activities including antibacterial, antifungal, antiin ammatory and anticancer effects [7]. In recent years, ALT has been reported to exert antitumor effect on many cancers, including lung cancer, gastric cancer, hepatic cancer, B-cell acute lymphoblastic leukemia, pancreatic cancer and breast cancer [8].…”