Effect of Red Raisins (Vitis Vinifera L.) Intake on the Level of Some Hematological Tests in a Group of Female Volunteers

Al-aboud, Nora M.

doi:10.26717/bjstr.2018.02.000764

Cited by 4 publications

(1 citation statement)

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“…Inconsistent results were obtained in a study by Al-aboud et al [ 173 ]. They showed that consuming 8 g of raisins ( Vitis vinifera L.) for 20 days resulted in increased haemoglobin and serum iron levels, an increase in ferritin, and a decrease in total iron binding capacity (TIBC) and transferrin.…”

Section: Possible Negative Consequences Of Blocking Iron Uptakementioning

confidence: 65%

Possible Side Effects of Polyphenols and Their Interactions with Medicines

Duda-Chodak

Tarko

2023

Molecules

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Polyphenols are an important component of plant-derived food with a wide spectrum of beneficial effects on human health. For many years, they have aroused great interest, especially due to their antioxidant properties, which are used in the prevention and treatment of many diseases. Unfortunately, as with any chemical substance, depending on the conditions, dose, and interactions with the environment, it is possible for polyphenols to also exert harmful effects. This review presents a comprehensive current state of the knowledge on the negative impact of polyphenols on human health, describing the possible side effects of polyphenol intake, especially in the form of supplements. The review begins with a brief overview of the physiological role of polyphenols and their potential use in disease prevention, followed by the harmful effects of polyphenols which are exerted in particular situations. The individual chapters discuss the consequences of polyphenols’ ability to block iron uptake, which in some subpopulations can be harmful, as well as the possible inhibition of digestive enzymes, inhibition of intestinal microbiota, interactions of polyphenolic compounds with drugs, and impact on hormonal balance. Finally, the prooxidative activity of polyphenols as well as their mutagenic, carcinogenic, and genotoxic effects are presented. According to the authors, there is a need to raise public awareness about the possible side effects of polyphenols supplementation, especially in the case of vulnerable subpopulations.

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Section: Possible Negative Consequences Of Blocking Iron Uptakementioning

confidence: 65%